navigating-angles-retrospective-analysis-one-year-outcomes-gonioscopy

Navigating the Angles: A Retrospective Analysis of One-year Outcomes of Gonioscopy-assisted Transluminal Trabeculotomy in Primary Open-angle Glaucoma

This study aimed to evaluate postoperative angle changes following gonioscopy-assisted transluminal trabeculotomy (GATT) in patients with primary ...

Chengdu First People's Hospital

To compare the efficacy and safety of 120-, 240-, and 360-degree goniotomy (GT) with or without phacoemulsification with intraocular lens implantation (PEI) for patients with primary open-angle glaucoma (POAG).

Influence of Goniotomy Size on Treatment Safety and Efficacy for Primary Open-Angle Glaucoma: A Multicenter Study.

Glaucoma is a common and complex neurodegenerative disease characterized by progressive loss of retinal ganglion cells (RGCs) and axons. Currently, there is no effective method to address the cause of RGCs degeneration. However, studies on neuroprotective strategies for optic neuropathy have increased in recent years. Cell replacement and neuroprotection are major strategies for treating glaucoma and optic neuropathy. Regenerative medicine research into the repair of optic nerve damage using stem cells has received considerable attention. Stem cells possess the potential for multidirectional differentiation abilities and are capable of producing RGC-friendly microenvironments through paracrine effects. This article reviews a thorough researches of recent advances and approaches in stem cell repair of optic nerve injury, raising the controversies and unresolved issues surrounding the future of stem cells.

Mesenchymal stem cells for repairing glaucomatous optic nerve.

The combination of phacoemulsification, goniosynechialysis and goniotomy is an effective treatment for primary angle closure glaucoma patients with cataract, and this is not linked to the extent of preoperative peripheral anterior synechiae.

Impact of Peripheral Anterior Synechiae on the Outcome of Combined Phacoemulsification, Goniosynechialysis, and Goniotomy for Primary Angle Closure Glaucoma and Cataract: A Multicenter Observational Study.

Corneal transplantation is a common treatment for corneal diseases. Secondary glaucoma after corneal transplantation is the second leading cause of failure of keratoplasty. This article reviews the mechanism and treatment of secondary glaucoma after corneal transplantation.

Mechanism and treatment of secondary glaucoma after corneal transplantation: a review.

Micropulse transscleral laser therapy for secondary angle-closure glaucoma in nanophthalmos: a case report.

N6-methyladenosine (m6A), a pivotal RNA modification, has garnered considerable attention in cell biology and disease research. m6A plays a critical role in the regulation of gene expression, cell proliferation, differentiation, and apoptosis, with particular relevance to the onset and progression of ocular diseases. This review examines the current research on m6A in ocular diseases, including keratitis, cataracts, glaucoma, retinopathy, thyroid ophthalmopathy, and ocular tumors, highlighting its functional significance and potential mechanisms in these conditions. Recent studies suggest that m6A modification influences cellular fate and pathophysiological processes by modulating the expression of key genes. However, a deeper understanding of the precise mechanisms underlying m6A action in ocular diseases is still needed. By synthesizing the existing literature, this review seeks to offer novel insights and identify potential therapeutic targets, thereby advancing clinical applications for ocular disease treatment.

N6-methyladenosine: a key regulator in ocular disease mechanisms and treatment.

To evaluate the 2-year efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) for normal-tension glaucoma (NTG).

Article	Year
Influence of Goniotomy Size on Treatment Safety and Efficacy for Primary Open-Angle Glaucoma: A Multicenter Study. American journal of ophthalmology\| PubMed ID: 37573988	2023
Mesenchymal stem cells for repairing glaucomatous optic nerve. International journal of ophthalmology\| PubMed ID: 38638254	2024
Impact of Peripheral Anterior Synechiae on the Outcome of Combined Phacoemulsification, Goniosynechialysis, and Goniotomy for Primary Angle Closure Glaucoma and Cataract: A Multicenter Obser... Journal of glaucoma\| PubMed ID: 38767510	2024
Mechanism and treatment of secondary glaucoma after corneal transplantation: a review. Frontiers in ophthalmology\| PubMed ID: 38984120	2024
Micropulse transscleral laser therapy for secondary angle-closure glaucoma in nanophthalmos: a case report. International journal of ophthalmology\| PubMed ID: 39026908	2024
N6-methyladenosine: a key regulator in ocular disease mechanisms and treatment. Cell death discovery\| PubMed ID: 41315216	2025
Two-year clinical outcomes of standalone gonioscopy-assisted transluminal trabeculotomy in normal-tension glaucoma. Frontiers in medicine\| PubMed ID: 42006874	2026

Ping Yu

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