Xiaowei Chen

Brain Research Center and State Key Laboratory of Trauma and Chemical Poisoning, Third Military Medical University

Affiliated withThird Military Medical University

Research Area

Biography

Xiaowei Chen has not added Biography.
If you are Xiaowei Chen and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
NMDA receptor-dependent multidendrite Ca(2+) spikes required for hippocampal burst firing in vivo. Neuron\| PubMed ID: 24560703	2014
Mechanisms of orexin A-evoked changes of intracellular calcium in primary cultured cortical neurons. Neuroreport\| PubMed ID: 15858425	2005
Postsynaptic excitation of prefrontal cortical pyramidal neurons by hypocretin-1/orexin A through the inhibition of potassium currents. Journal of neuroscience research\| PubMed ID: 16247802	2005
Effects of orexins on myoelectric activity of sphincter of Oddi in fasted rabbits. Acta pharmacologica Sinica\| PubMed ID: 16412271	2006
Modulatory effects of hypocretin-1/orexin-A with glutamate and gamma-aminobutyric acid on freshly isolated pyramidal neurons from the rat prefrontal cortex. Neuroscience letters\| PubMed ID: 16495001	2006
Hypocretin-1 potentiates NMDA receptor-mediated somatodendritic secretion from locus ceruleus neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18354023	2008
DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release. The Journal of cell biology\| PubMed ID: 18504299	2008
The modulation of orexin A on HCN currents of pyramidal neurons in mouse prelimbic cortex. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 19915095	2010
Reactivation of the same synapses during spontaneous up states and sensory stimuli. Cell reports\| PubMed ID: 23810558	2013
Dendritic function in vivo. Trends in neurosciences\| PubMed ID: 25432423	2015
Thyroid Hormone-Otx2 Signaling Is Required for Embryonic Ventral Midbrain Neural Stem Cells Differentiated into Dopamine Neurons. Stem cells and development\| PubMed ID: 25867707	2015
Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cells. Journal of pineal research\| PubMed ID: 27396692	2016
Sensory Response of Transplanted Astrocytes in Adult Mammalian Cortex In Vivo. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 27405333	2016
Primary Auditory Cortex is Required for Anticipatory Motor Response. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 28379350	2017
Targeted Patching and Dendritic Ca Imaging in Nonhuman Primate Brain in vivo. Scientific reports\| PubMed ID: 28588297	2017
Sensory response in host and engrafted astrocytes of adult brain in Vivo. Glia\| PubMed ID: 28631858	2017
Functional imaging of neuronal activity of auditory cortex by using Cal-520 in anesthetized and awake mice. Biomedical optics express\| PubMed ID: 28663893	2017
Enhancement of Neural Salty Preference in Obesity. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 29055956	2017
Enjoyment of Spicy Flavor Enhances Central Salty-Taste Perception and Reduces Salt Intake and Blood Pressure. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 29089370	2017
NeuroSeg: automated cell detection and segmentation for in vivo two-photon Ca imaging data. Brain structure & function\| PubMed ID: 29124351	2018
Frequency selectivity of echo responses in the mouse primary auditory cortex. Scientific reports\| PubMed ID: 29311673	2018
Two-Photon Functional Imaging of the Auditory Cortex in Behaving Mice: From Neural Networks to Single Spines. Frontiers in neural circuits\| PubMed ID: 29740289	2018
A Visual-Cue-Dependent Memory Circuit for Place Navigation. Neuron\| PubMed ID: 29909996	2018
The paraventricular thalamus is a critical thalamic area for wakefulness. Science (New York, N.Y.)\| PubMed ID: 30361367	2018
A corticopontine circuit for initiation of urination. Nature neuroscience\| PubMed ID: 30361547	2018
Molecular Engineering of an Organic NIR-II Fluorophore with Aggregation-Induced Emission Characteristics for In Vivo Imaging. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 30925013	2019
Simultaneous Measurement of Neuronal Activity in the Pontine Micturition Center and Cystometry in Freely Moving Mice. Frontiers in neuroscience\| PubMed ID: 31293380	2019
Impairment of Bitter Taste Sensor Transient Receptor Potential Channel M5-Mediated Aversion Aggravates High-Salt Intake and Hypertension. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 31401881	2019
Impaired D2 receptor-dependent dopaminergic transmission in prefrontal cortex of awake mouse model of Parkinson's disease. Brain : a journal of neurology\| PubMed ID: 31504219	2019
Multichannel fiber photometry for mapping axonal terminal activity in a restricted brain region in freely moving mice. Neurophotonics\| PubMed ID: 31528656	2019
MATRIEX imaging: multiarea two-photon real-time in vivo explorer. Light, science & applications\| PubMed ID: 31798848	2019
Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer's disease-type pathology and cognitive deficits in APP/PS1 mice. Translational psychiatry\| PubMed ID: 32661266	2020
Blood cell-produced amyloid-β induces cerebral Alzheimer-type pathologies and behavioral deficits. Molecular psychiatry\| PubMed ID: 32681097	2021
Spatial Navigation. Advances in experimental medicine and biology\| PubMed ID: 32852741	2020
Single-neuron representation of learned complex sounds in the auditory cortex. Nature communications\| PubMed ID: 32868773	2020
Low-glucose-sensitive TRPC6 dysfunction drives hypoglycemia-induced cognitive impairment in diabetes. Clinical and translational medicine\| PubMed ID: 33135341	2020
Neural spike train reconstruction from calcium imaging via a signal-shape composition model. Science China. Life sciences\| PubMed ID: 33219904	2020
Monitoring Astrocytic Ca Activity in Freely Behaving Mice. Frontiers in cellular neuroscience\| PubMed ID: 33343304	2020
Restoration of Two-Photon Ca Imaging Data Through Model Blind Spatiotemporal Filtering. Frontiers in neuroscience\| PubMed ID: 33935628	2021
Non-invasive, opsin-free mid-infrared modulation activates cortical neurons and accelerates associative learning. Nature communications\| PubMed ID: 33980868	2021
PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 34244441	2021
Fear learning induces α7-nicotinic acetylcholine receptor-mediated astrocytic responsiveness that is required for memory persistence. Nature neuroscience\| PubMed ID: 34782794	2021
Neural circuit control of innate behaviors. Science China. Life sciences\| PubMed ID: 34985643	2022
Brain-wide projection reconstruction of single functionally defined neurons. Nature communications\| PubMed ID: 35318336	2022
An entorhinal-visual cortical circuit regulates depression-like behaviors. Molecular psychiatry\| PubMed ID: 35388184	2022
Correction: An entorhinal-visual cortical circuit regulates depression-like behaviors. Molecular psychiatry\| PubMed ID: 35474105	2022
Time-restricted feeding entrains long-term behavioral changes through the IGF2-KCC2 pathway. iScience\| PubMed ID: 35521538	2022
Fast and Accurate Motion Correction for Two-Photon Ca Imaging in Behaving Mice. Frontiers in neuroinformatics\| PubMed ID: 35559212	2022
Optical Fiber-Based Recording of Climbing Fiber Ca Signals in Freely Behaving Mice. Biology\| PubMed ID: 35741428	2022
Engrafted glial progenitor cells yield long-term integration and sensory improvement in aged mice. Stem cell research & therapy\| PubMed ID: 35765112	2022
Ventrolateral Periaqueductal Gray Neurons Are Active During Urination. Frontiers in cellular neuroscience\| PubMed ID: 35813503	2022
Melanopsin retinal ganglion cells mediate light-promoted brain development. Cell\| PubMed ID: 35944541	2022
REM sleep-active hypothalamic neurons may contribute to hippocampal social-memory consolidation. Neuron\| PubMed ID: 36272414	2022
Astrocytes exhibit diverse Ca changes at subcellular domains during brain aging. Frontiers in aging neuroscience\| PubMed ID: 36389078	2022
Daily two-photon neuronal population imaging with targeted single-cell electrophysiology and subcellular imaging in auditory cortex of behaving mice. Frontiers in cellular neuroscience\| PubMed ID: 36937184	2023
A Sleep-Specific Midbrain Target for Sevoflurane Anesthesia. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 36961096	2023
Hippocampal ripples correlate with memory performance in humans. Brain research\| PubMed ID: 37080267	2023
NeuroSeg-II: A deep learning approach for generalized neuron segmentation in two-photon Ca imaging. Frontiers in cellular neuroscience\| PubMed ID: 37091918	2023
Ten-kilohertz two-photon microscopy imaging of single-cell dendritic activity and hemodynamics . Neurophotonics\| PubMed ID: 37152357	2023
Optrode recording of an entorhinal-cortical circuit in freely moving mice. Biomedical optics express\| PubMed ID: 37206131	2023
Rabies virus-based labeling of layer 6 corticothalamic neurons for two-photon imaging . iScience\| PubMed ID: 37250327	2023
Spatial memory requires hypocretins to elevate medial entorhinal gamma oscillations. Neuron\| PubMed ID: 37944520	2024
Holistic bursting cells store long-term memory in auditory cortex. Nature communications\| PubMed ID: 38062015	2023
Hypothalamic supramammillary neurons that project to the medial septum modulate wakefulness in mice. Communications biology\| PubMed ID: 38087004	2023
Preserving cognitive function in patients with Alzheimer's disease: The Alzheimer's disease neuroprotection research initiative (ADNRI). Neuroprotection\| PubMed ID: 38223913	2023
BNST GABAergic neurons modulate wakefulness over sleep and anesthesia. Communications biology\| PubMed ID: 38503808	2024
STPoseNet: A real-time spatiotemporal network model for robust mouse pose estimation. iScience\| PubMed ID: 38711440	2024
NeuroSeg-III: efficient neuron segmentation in two-photon Ca imaging data using self-supervised learning. Biomedical optics express\| PubMed ID: 38855703	2024
Electrophysiological activity pattern of mouse hippocampal CA1 and dentate gyrus under isoflurane anesthesia. Frontiers in cellular neuroscience\| PubMed ID: 39104439	2024
Astrocyte-derived lactate aggravates brain injury of ischemic stroke in mice by promoting the formation of protein lactylation. Theranostics\| PubMed ID: 39113798	2024
Homeostatic Shrinkage of Dendritic Spines Requires Melatonin Type 3 Receptor Activation During Sleep. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 39119847	2024
Mapping multi-regional functional connectivity of astrocyte-neuronal networks during behaviors. Neurophotonics\| PubMed ID: 39554692	2024
Non-image-forming photoreceptors improve visual orientation selectivity and image perception. Neuron\| PubMed ID: 39694031	2025
Roles of blood monocytes carrying TREM2 mutation in pathogenesis of Alzheimer's disease and its therapeutic potential in APP/PS1 mice. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 39740209	2025
Possible brain regions involved in parturition in mice. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 39829234	2025
Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances. Signal transduction and targeted therapy\| PubMed ID: 40059211	2025
Pitolisant alleviates brain network dysfunction and cognitive deficits in a mouse model of Alzheimer's disease. Translational psychiatry\| PubMed ID: 40185739	2025
A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement. Life medicine\| PubMed ID: 40226444	2025
A parallel tonotopically arranged thalamocortical circuit for sound processing. Neuron\| PubMed ID: 40239654	2025
Burst firing represents learned composite stimuli in primary sensory cortices. Current opinion in neurobiology\| PubMed ID: 40334497	2025
Brain-wide 3D neuron detection and mapping with deep learning. Neurophotonics\| PubMed ID: 40401216	2025
Withaferin A Rescues Brain Network Dysfunction and Cognitive Deficits in a Mouse Model of Alzheimer's Disease. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 40573212	2025
Parvalbumin interneurons are essential for tonotopy strength in the auditory cortex. Science bulletin\| PubMed ID: 40617701	2025
Astrocytes in the medial entorhinal cortex are required for spatial exploration. Cell reports\| PubMed ID: 40844874	2025
Amyloid β-dependent neuronal silencing through synaptic decoupling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 40875806	2025
Therapeutic potential of 40 Hz flickering light stimulation in Alzheimer's disease: Mechanisms, evidence, and controversies. Journal of Alzheimer's disease : JAD\| PubMed ID: 41124366	2025
Tonotopy is not preserved in a descending stage of auditory cortex. eLife\| PubMed ID: 41143504	2025
Adenosine signaling in the habenula: a depression-myocardial infarction nexus. Science bulletin\| PubMed ID: 41290466	2025
A flexible and biocompatible trilayer coaxial heterogeneous structure microfiber electrode for long-term electrophysiological recordings in freely moving mice. Nanoscale\| PubMed ID: 41401045	2026
Targeting brain hubs of ictal fast ripple activity to reduce seizures in patients with drug-resistant epilepsy. Science translational medicine\| PubMed ID: 41442498	2025
Notch1 cervical cancer cells may promote perineural invasion by secreting neurotrophin-4. Scientific reports\| PubMed ID: 41507526	2026
Non-invasive and painless mid-infrared modulation increases collagen in human and mouse skin. Journal of advanced research\| PubMed ID: 41620173	2026
Tonotopic organization in the basal region of the ventromedial nucleus of the thalamus revealed by fiber photometry recording. Neurophotonics\| PubMed ID: 41625482	2026
Characterization of a novel aminoglycoside resistance gene, , identified from S24. Frontiers in microbiology\| PubMed ID: 41929691	2026