Chunlai Nie

Department of Biotherapy, West China Hospital, Sichuan University

Affiliated withWest China Hospital, Sichuan University

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Mitochondrial p53 phosphorylation induces Bak-mediated and caspase-independent cell death. Oncotarget\| PubMed ID: 25980443	2015
BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells. PloS one\| PubMed ID: 21655183	2011
Proapoptotic protein Smac mediates apoptosis in cisplatin-resistant ovarian cancer cells when treated with the anti-tumor agent AT101. The Journal of biological chemistry\| PubMed ID: 22052903	2012
PNAS-4, an Early DNA Damage Response Gene, Induces S Phase Arrest and Apoptosis by Activating Checkpoint Kinases in Lung Cancer Cells. The Journal of biological chemistry\| PubMed ID: 25918161	2015
Discovery of a potent microtubule-targeting agent: Synthesis and biological evaluation of water-soluble amino acid prodrug of combretastatin A-4 derivatives. Bioorganic & medicinal chemistry letters\| PubMed ID: 25933592	2015
Mcl-1 expression and JNK activation induces a threshold for apoptosis in Bcl-xL-overexpressing hematopoietic cells. Oncotarget\| PubMed ID: 28038464	2017
The role of ROS and subsequent DNA-damage response in PUMA-induced apoptosis of ovarian cancer cells. Oncotarget\| PubMed ID: 28423586	2017
Guanylate-binding protein 2 regulates Drp1-mediated mitochondrial fission to suppress breast cancer cell invasion. Cell death & disease\| PubMed ID: 29072687	2017
PP2A mediates apoptosis or autophagic cell death in multiple myeloma cell lines. Oncotarget\| PubMed ID: 29113343	2017
Long non-coding RNA SPRY4-IT1 promotes cell proliferation and invasion by regulation of Cdc20 in pancreatic cancer cells. PloS one\| PubMed ID: 29489909	2018
ARD1 contributes to IKKβ-mediated breast cancer tumorigenesis. Cell death & disease\| PubMed ID: 30154412	2018
Correction: Guanylate-binding protein 2 regulates Drp1-mediated mitochondrial fission to suppress breast cancer cell invasion. Cell death & disease\| PubMed ID: 30425235	2018
Diosgenin exhibits tumor suppressive function via down-regulation of EZH2 in pancreatic cancer cells. Cell cycle (Georgetown, Tex.)\| PubMed ID: 31213123	2019
Intercellular Adhesion Molecule-1 as Target for CAR-T-Cell Therapy of Triple-Negative Breast Cancer. Frontiers in immunology\| PubMed ID: 33072116	2020
Development of multivalent nanobodies blocking SARS-CoV-2 infection by targeting RBD of spike protein. Journal of nanobiotechnology\| PubMed ID: 33514385	2021
JNK initiates Beclin-1 dependent autophagic cell death against Akt activation. Experimental cell research\| PubMed ID: 35306025	2022
Genome-scale CRISPR-Cas9 screen reveals novel regulators of B7-H3 in tumor cells. Journal for immunotherapy of cancer\| PubMed ID: 35768165	2022
Kidney microbiota dysbiosis contributes to the development of hypertension. Gut microbes\| PubMed ID: 36369946	2022
Evaluation of B7-H3 Targeted Immunotherapy in a 3D Organoid Model of Craniopharyngioma. Biomolecules\| PubMed ID: 36551172	2022
Loss of furin site enhances SARS-CoV-2 spike protein pseudovirus infection. Gene\| PubMed ID: 36577450	2023
mRNA-Engineered CD5-CAR-γδT Cells for the Immunotherapy of T-Cell Acute Lymphoblastic Leukemia. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 39013083	2024
Targeting oncogenic transcriptional factor c-myc by oligonucleotide PROTAC for the treatment of hepatocellular carcinoma. European journal of medicinal chemistry\| PubMed ID: 39447458	2024
Myeloid-derived suppressor cell-targeted virus-like particles synergistically activate innate immune response for cancer immunotherapy. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 40049520	2025
YMN-V115: a novel humanized BCMA/GPRC5D/CD3 trispecific antibody in relapsed/refractory multiple myeloma. Journal for immunotherapy of cancer\| PubMed ID: 41708144	2026
A novel CLDN6 nanobody-based bispecific T-cell engager delivered by self-amplifying RNA platform exhibits potent antitumor efficacy. Journal of nanobiotechnology\| PubMed ID: 41882748	2026
Dynamics of severity-associated immune remodeling by granulocytes and macrophages in acute lung injury. iScience\| PubMed ID: 42111184	2026