construction-validation-nomogram-to-identify-mucus-obstruction

Construction and Validation of A Nomogram to Identify Mucus Obstruction In Patients With Chronic Obstructive Pulmonary Disease

Small airway mucus impaction in chest computed tomography (CT) is a clinically significant finding in chronic obstructive pulmonary disease (COPD), ...

The First Affiliated Hospital of Shenzhen University (Shenzhen Second People's Hospital)

CD147/EMMPRIN (extracellular matrix metalloproteinase inducer) plays an important role in tumor progression and a number of studies have suggested that it is an indicator of tumor prognosis. This current meta-analysis systematically reevaluated the predictive potential of CD147/EMMPRIN in various cancers. We searched PubMed and Embase databases to screen the literature. Fixed-effect and random-effect meta-analytical techniques were used to correlate CD147 expression with outcome measures. A total of 53 studies that included 68 datasets were eligible for inclusion in the final analysis. We found a significant association between CD147/EMMPRIN overexpression and adverse tumor outcomes, such as overall survival, disease-specific survival, progression-free survival, metastasis-free survival or recurrence-free survival, irrespective of the model analysis. In addition, CD147/EMMPRIN overexpression predicted a high risk for chemotherapy drugs resistance. CD147/EMMPRIN is a central player in tumor progression and predicts a poor prognosis, including in patients who have received chemo-radiotherapy. Our results provide the evidence that CD147/EMMPRIN could be a potential therapeutic target for cancers.

CD147/EMMPRIN overexpression and prognosis in cancer: A systematic review and meta-analysis.

The rapid diagnosis of respiratory virus infection through breath and blow remains challenging. Here we develop a wireless, battery-free, multifunctional pathogenic infection diagnosis system (PIDS) for diagnosing SARS-CoV-2 infection and symptom severity by blow and breath within 110 s and 350 s, respectively. The accuracies reach to 100% and 92% for evaluating the infection and symptom severity of 42 participants, respectively. PIDS realizes simultaneous gaseous sample collection, biomarker identification, abnormal physical signs recording and machine learning analysis. We transform PIDS into other miniaturized wearable or portable electronic platforms that may widen the diagnostic modes at home, outdoors and public places. Collectively, we demonstrate a general-purpose technology for rapidly diagnosing respiratory pathogenic infection by breath and blow, alleviating the technical bottleneck of saliva and nasopharyngeal secretions. PIDS may serve as a complementary diagnostic tool for other point-of-care techniques and guide the symptomatic treatment of viral infections.

Wireless, battery-free, multifunctional integrated bioelectronics for respiratory pathogens monitoring and severity evaluation.

 () is a rare human pathogen known to cause severe conditions such as sepsis, fungemia, endocarditis, and peritonitis, often resulting in high mortality rates. This report presents a case of a febrile 66-year-old male with a urinary tract infection and fungemia caused by . The patient had additional complications of pulmonary thromboembolism (PTE) and deep venous thrombosis (DVT) in the left lower extremity. Notably, the pathogen was isolated in both urine and blood cultures, an uncommon finding in immunocompetent patients. Treatment with fluconazole was initiated based on the antifungal susceptibility testing (AFST) results. Following treatment, the patient experienced a gradual resolution of fever and urinary tract infection symptoms. Concurrently, anticoagulant therapy was administered for the management of PTE and DVT. The patient was eventually discharged in a stable condition.

A Case Report of Urinary Tract Infection and Fungemia Due to  Complicated with Pulmonary Thromboembolism.

Pulmonary embolism (PE) is a serious and potentially life-threatening condition that requires prompt diagnosis and treatment. Identifying risk factors and diagnostic markers can aid in the early detection and management of this condition.

Pulmonary embolism incidence among patient admitted under psychiatry department: a case-control study.

Dental caries is a localized deterioration of hard tissues caused by acidic by-products of bacterial fermentation of dietary carbohydrates. However, except for fluoride, there were few studies focusing on the direct association between other trace elements. This study aimed to explore how other trace elements affect dental caries.

Association between trace elements and dental caries in the USA: analysis of data from serial cross-sectional surveys, 2010-2016.

To develop and validate the Anhui Environmental Exposure Questionnaire (AEEQ) and evaluate whether its composite score independently predicts incident cerebral haemorrhage in older adults.

Ambient air pollution, sleep quality, and cerebral hemorrhage risk in older adults: development and validation of the Anhui environmental exposure questionnaire in a 460 participant cohort study.

The relationship between fluid responsiveness and right-and left-sided congestion remains underexplored. This study aimed to delineate the dynamic behaviour of venous congestion and extravascular lung water index (EVLWI) during a fluid challenge depending on the concomitant changes in cardiac index (CI).

Fluid responsiveness and changes in venous congestion and lung water during volume expansion in critically ill patients: a multicentre observational study.

Article	Year
CD147/EMMPRIN overexpression and prognosis in cancer: A systematic review and meta-analysis. Scientific reports\| PubMed ID: 27608940	2016
Wireless, battery-free, multifunctional integrated bioelectronics for respiratory pathogens monitoring and severity evaluation. Nature communications\| PubMed ID: 37985765	2023
A Case Report of Urinary Tract Infection and Fungemia Due to Complicated with Pulmonary Thromboembolism. Infection and drug resistance\| PubMed ID: 38192331	2024
Pulmonary embolism incidence among patient admitted under psychiatry department: a case-control study. Frontiers in psychiatry\| PubMed ID: 39220184	2024
Association between trace elements and dental caries in the USA: analysis of data from serial cross-sectional surveys, 2010-2016. BMC oral health\| PubMed ID: 40108634	2025
Ambient air pollution, sleep quality, and cerebral hemorrhage risk in older adults: development and validation of the Anhui environmental exposure questionnaire in a 460 participant cohort s... Frontiers in public health\| PubMed ID: 41323628	2025
Fluid responsiveness and changes in venous congestion and lung water during volume expansion in critically ill patients: a multicentre observational study. Critical care (London, England)\| PubMed ID: 41572378	2026

Rui Shi

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