real-time-label-free-imaging-quantitative-analysis-macrophage

Real-Time Label-Free Imaging and Quantitative Analysis of Macrophage Morphodynamics Using Optical Diffraction Tomography

This study establishes a label-free optical diffraction tomography (ODT)-based workflow for live-cell imaging and analysis to observe time-dependent ...

Chengdu University of Traditional Chinese Medicine

The high incidence of Gleason score upgrade (GSU) can lead urologists to underestimate tumor aggressiveness, resulting in suboptimal treatment decisions. This study aimed to develop an interpretable machine learning model to predict the risk of GSU in individuals with prostate cancer (PCa) based on readily available clinical parameters.

Development and validation of an interpretable machine learning model for predicting Gleason score upgrade in prostate cancer.

Scutellaria baicalensis, a traditional Chinese medicine herb, has been classically used to treat diarrhea and dysentery caused by damp heat in Traditional Chinese Medicine. And it has been demonstrated to alleviate colonic mucosal inflammation in ulcerative colitis. However, the mechanism through which its main active ingredient, baicalin, alleviates ulcerative colitis remains unclear.

Article	Year
Development and validation of an interpretable machine learning model for predicting Gleason score upgrade in prostate cancer. Translational andrology and urology\| PubMed ID: 40687645	2025
Baicalin ameliorates ulcerative colitis by regulating macrophage polarization through the JAK1/STAT1/SOCS1 pathway. Journal of ethnopharmacology\| PubMed ID: 41423154	2026

Si-yu Liu

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