Zhen Cheng

Department of Urology, Liaocheng Second People's Hospital

Affiliated withLiaocheng Second People's Hospital

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2026

Other Publications

Article	Year
Alpha-melanocyte-stimulating hormone peptide analogs labeled with technetium-99m and indium-111 for malignant melanoma targeting. Cancer\| PubMed ID: 11877745	2002
Modification of the structure of a metallopeptide: synthesis and biological evaluation of (111)In-labeled DOTA-conjugated rhenium-cyclized alpha-MSH analogues. Journal of medicinal chemistry\| PubMed ID: 12086490	2002
[Medical history from SARS to pneumonia]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences\| PubMed ID: 12914233	2003
Radioiodination of rhenium cyclized alpha-melanocyte-stimulating hormone resulting in enhanced radioactivity localization and retention in melanoma. Cancer research\| PubMed ID: 14973076	2004
Tests involving humans subjects: old and new in China. The Journal of clinical ethics\| PubMed ID: 15202351	2004
A new strategy to screen molecular imaging probe uptake in cell culture without radiolabeling using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 15872363	2005
[99mTcOAADT]-(CH2)2-NEt2: a potential small-molecule single-photon emission computed tomography probe for imaging metastatic melanoma. Cancer research\| PubMed ID: 15958536	2005
microPET imaging of glioma integrin {alpha}v{beta}3 expression using (64)Cu-labeled tetrameric RGD peptide. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 16204722	2005
Reproducibility of 3'-deoxy-3'-(18)F-fluorothymidine microPET studies in tumor xenografts in mice. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 16269599	2005
Near-infrared fluorescent RGD peptides for optical imaging of integrin alphavbeta3 expression in living mice. Bioconjugate chemistry\| PubMed ID: 16287239	2005
Imaging chemically modified adenovirus for targeting tumors expressing integrin alphavbeta3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 16391197	2006
An aggressive systematic strategy for acute respiratory distress syndrome caused by severe pneumonia after renal transplantation. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 16441359	2006
[The understanding of western medicine on disease in the 18th century.] Zhonghua yi shi za zhi (Beijing, China : 1980)\| PubMed ID: 16469246	2005
Near-infrared fluorescent deoxyglucose analogue for tumor optical imaging in cell culture and living mice. Bioconjugate chemistry\| PubMed ID: 16704203	2006
Pulmonary Lophomonas blattarum infection in patients with kidney allograft transplantation. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 17081231	2006
Medical images edge detection based on mathematical morphology. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 17281756	2005
Development of a Portable Blood Sugar Apparatus and GOD Enzyme Strip. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 17282159	2005
In vivo bioluminescence tumor imaging of RGD peptide-modified adenoviral vector encoding firefly luciferase reporter gene. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 17297551	2007
64Cu-labeled alpha-melanocyte-stimulating hormone analog for microPET imaging of melanocortin 1 receptor expression. Bioconjugate chemistry\| PubMed ID: 17348700	2007
Fluorescent fructose derivatives for imaging breast cancer cells. Bioconjugate chemistry\| PubMed ID: 17444608	2007
Small-animal PET of melanocortin 1 receptor expression using a 18F-labeled alpha-melanocyte-stimulating hormone analog. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 17504880	2007
microPET-based biodistribution of quantum dots in living mice. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 17704240	2007
Bisdeoxycoelenterazine derivatives for improvement of bioluminescence resonance energy transfer assays. Journal of the American Chemical Society\| PubMed ID: 17850082	2007
Breast cancer detection based on multi-frequency EIS measurement. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 18002918	2007
Real-time intravital imaging of RGD-quantum dot binding to luminal endothelium in mouse tumor neovasculature. Nano letters\| PubMed ID: 18386933	2008
Small-animal PET imaging of human epidermal growth factor receptor type 2 expression with site-specific 18F-labeled protein scaffold molecules. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 18413392	2008
Direct site-specific radiolabeling of an Affibody protein with 4-[18F]fluorobenzaldehyde via oxime chemistry. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 18481153	2008
Targeted microbubbles for imaging tumor angiogenesis: assessment of whole-body biodistribution with dynamic micro-PET in mice. Radiology\| PubMed ID: 18695212	2008
Carbon nanotubes as photoacoustic molecular imaging agents in living mice. Nature nanotechnology\| PubMed ID: 18772918	2008
Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 19051182	2009
[Real world instantaneous emission simulation for light-duty diesel vehicle]. Huan jing ke xue= Huanjing kexue / [bian ji, Zhongguo ke xue yuan huan jing ke xue wei yuan hui "Huan jing ke xue" bian ji wei yuan hui.]\| PubMed ID: 19143404	2008
A novel method for direct site-specific radiolabeling of peptides using [18F]FDG. Bioconjugate chemistry\| PubMed ID: 19226160	2009
Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects. Cancer research\| PubMed ID: 19276378	2009
Engineered two-helix small proteins for molecular recognition. Chembiochem : a European journal of chemical biology\| PubMed ID: 19422008	2009
Photoactivable bioluminescent probes for imaging luciferase activity. Chemical communications (Cambridge, England)\| PubMed ID: 19568622	2009
Visualizing implanted tumors in mice with magnetic resonance imaging using magnetotactic bacteria. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19671860	2009
Application of the indirect fluorescent antibody assay in the study of malaria infection in the Yangtze River Three Gorges Reservoir, China. Malaria journal\| PubMed ID: 19678949	2009
A 2-helix small protein labeled with 68Ga for PET imaging of HER2 expression. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 19690041	2009
Melanin-targeted preclinical PET imaging of melanoma metastasis. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 19759116	2009
64Cu-labeled affibody molecules for imaging of HER2 expressing tumors. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 19779897	2010
PET of malignant melanoma using 18F-labeled metallopeptides. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 19837749	2009
An engineered knottin peptide labeled with 18F for PET imaging of integrin expression. Bioconjugate chemistry\| PubMed ID: 19908826	2009
Ultrasmall near-infrared non-cadmium quantum dots for in vivo tumor imaging. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 19911392	2010
Comparative Study on Separation and Purification of Isoflavones from the Seeds and Sprouts of Chickpea by HSCCC. Journal of liquid chromatography & related technologies\| PubMed ID: 20046900	2009
Evaluation of a (64)Cu-labeled cystine-knot peptide based on agouti-related protein for PET of tumors expressing alphavbeta3 integrin. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 20124048	2010
A Dual-Labeled Knottin Peptide for PET and Near-Infrared Fluorescence Imaging of Integrin Expression in Living Subjects. Bioconjugate chemistry\| PubMed ID: 20131753	2010
Protein scaffold-based molecular probes for cancer molecular imaging. Amino acids\| PubMed ID: 20174842	2011
Molecular optical imaging with radioactive probes. PloS one\| PubMed ID: 20208993	2010
In vivo tumor-targeted fluorescence imaging using near-infrared non-cadmium quantum dots. Bioconjugate chemistry\| PubMed ID: 20369817	2010
Near-infrared quantum dots as optical probes for tumor imaging. Current topics in medicinal chemistry\| PubMed ID: 20388111	2010
Assessing the effects of acetochlor on soil fungal communities by DGGE and clone library analysis. Ecotoxicology (London, England)\| PubMed ID: 20401531	2010
Small-animal PET imaging of human epidermal growth factor receptor positive tumor with a 64Cu labeled affibody protein. Bioconjugate chemistry\| PubMed ID: 20402512	2010
Ferritin enhances SPIO tracking of C6 rat glioma cells by MRI. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 20440566	2011
Radiation-luminescence-excited quantum dots for in vivo multiplexed optical imaging. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 20473988	2010
Quantum dots: Small 10/2010. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 20486214	2010
Molecular probes for malignant melanoma imaging. Current pharmaceutical biotechnology\| PubMed ID: 20497118	2010
In vivo near-infrared fluorescence imaging of cancer with nanoparticle-based probes. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology\| PubMed ID: 20564463	2010
Cy5.5-labeled Affibody molecule for near-infrared fluorescent optical imaging of epidermal growth factor receptor positive tumors. Journal of biomedical optics\| PubMed ID: 20615009	2010
HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging. Chemical communications (Cambridge, England)\| PubMed ID: 20730157	2010
Dynamic visualization of RGD-quantum dot binding to tumor neovasculature and extravasation in multiple living mouse models using intravital microscopy. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 20862677	2010
Near-infrared fluorescent nanoprobes for cancer molecular imaging: status and challenges. Trends in molecular medicine\| PubMed ID: 20870460	2010
De novo development of circulating anti-endothelial cell antibodies rather than pre-existing antibodies is associated with post-transplant allograft rejection. Kidney international\| PubMed ID: 20980975	2011
Effects of nanoparticle size on cellular uptake and liver MRI with polyvinylpyrrolidone-coated iron oxide nanoparticles. ACS nano\| PubMed ID: 21043459	2010
PET imaging of tumor neovascularization in a transgenic mouse model with a novel 64Cu-DOTA-knottin peptide. Cancer research\| PubMed ID: 21062977	2010
Radiofluorinated rhenium cyclized Î±-MSH analogues for PET imaging of melanocortin receptor 1. Bioconjugate chemistry\| PubMed ID: 21073170	2010
In vivo imaging of embryonic stem cell therapy. European journal of nuclear medicine and molecular imaging\| PubMed ID: 21107558	2011
Reproducibility study of [(18)F]FPP(RGD)2 uptake in murine models of human tumor xenografts. European journal of nuclear medicine and molecular imaging\| PubMed ID: 21125268	2011
Affibody-based nanoprobes for HER2-expressing cell and tumor imaging. Biomaterials\| PubMed ID: 21147502	2011
Preliminary evaluation of (177)Lu-labeled knottin peptides for integrin receptor-targeted radionuclide therapy. European journal of nuclear medicine and molecular imaging\| PubMed ID: 21153409	2011
Optical imaging of reporter gene expression using a positron-emission-tomography probe. Journal of biomedical optics\| PubMed ID: 21198146	2010
Radiolabeled affibody-albumin bioconjugates for HER2-positive cancer targeting. Bioconjugate chemistry\| PubMed ID: 21299201	2011
Affibody-functionalized gold-silica nanoparticles for Raman molecular imaging of the epidermal growth factor receptor. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 21302357	2011
Functional mutation of multiple solvent-exposed loops in the Ecballium elaterium trypsin inhibitor-II cystine knot miniprotein. PloS one\| PubMed ID: 21364742	2011
Structure-based repurposing of FDA-approved drugs as TNF-Î± inhibitors. ChemMedChem\| PubMed ID: 21365767	2011
Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer. Biochimie\| PubMed ID: 21377506	2011
Macrocyclic chelator assembled RGD multimers for tumor targeting. Bioorganic & medicinal chemistry letters\| PubMed ID: 21524578	2011
Enzyme-responsive multifunctional magnetic nanoparticles for tumor intracellular drug delivery and imaging. Chemistry, an Asian journal\| PubMed ID: 21548100	2011
Synthesis and radioluminescence of PEGylated Eu(3+) -doped nanophosphors as bioimaging probes. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 21557339	2011
Elevated expression of CUEDC2 protein confers endocrine resistance in breast cancer. Nature medicine\| PubMed ID: 21572428	2011
Preclinical evaluation of Raman nanoparticle biodistribution for their potential use in clinical endoscopy imaging. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 21608124	2011
One-step radiosynthesis of Â¹â¸F-AlF-NOTA-RGDâ‚‚ for tumor angiogenesis PET imaging. European journal of nuclear medicine and molecular imaging\| PubMed ID: 21617974	2011
Adipose tissue-derived stem cells display a proangiogenic phenotype on 3D scaffolds. Journal of biomedical materials research. Part A\| PubMed ID: 21630430	2011
Cdk1-phosphorylated CUEDC2 promotes spindle checkpoint inactivation and chromosomal instability. Nature cell biology\| PubMed ID: 21743465	2011
A novel 18F-labeled two-helix scaffold protein for PET imaging of HER2-positive tumor. European journal of nuclear medicine and molecular imaging\| PubMed ID: 21761266	2011
Molecular image-guided theranostic and personalized medicine. Journal of biomedicine & biotechnology\| PubMed ID: 21765636	2011
Direct analysis of oligosaccharides and alpha hydroxy acids in fruits using electrosonic spray ionization mass spectrometry. The Analyst\| PubMed ID: 21804962	2011
[American surgeon J. P. Webster and the beginning of plastic surgery in China]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery\| PubMed ID: 21838006	2011
Luminescent detection of DNA-binding proteins. Nucleic acids research\| PubMed ID: 21967849	2012
Cobalt-doped cadmium selenide colloidal nanowires. Chemical communications (Cambridge, England)\| PubMed ID: 21975534	2011
In vivo targeting of HER2-positive tumor using 2-helix affibody molecules. Amino acids\| PubMed ID: 21984380	2011
Primary focal segmental glomerulosclerosis in nephrotic patients: common complications and risk factors. Journal of nephrology\| PubMed ID: 22009935	2012
Harnessing the power of radionuclides for optical imaging: Cerenkov luminescence imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 22080446	2011
Non-invasive imaging of cysteine cathepsin activity in solid tumors using a 64Cu-labeled activity-based probe. PloS one\| PubMed ID: 22132198	2011
A novel clinically translatable fluorescent nanoparticle for targeted molecular imaging of tumors in living subjects. Nano letters\| PubMed ID: 22172022	2012
PET Imaging of Integrin Positive Tumors Using F Labeled Knottin Peptides. Theranostics\| PubMed ID: 22211146	2011
Optical imaging with her2-targeted affibody molecules can monitor hsp90 treatment response in a breast cancer xenograft mouse model. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 22235098	2012
Comparative evaluation of light-trap catches, electric motor mosquito catches and human biting catches of Anopheles in the Three Gorges Reservoir. PloS one\| PubMed ID: 22235256	2012
Inâ€…vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles. Angewandte Chemie (International ed. in English)\| PubMed ID: 22241651	2012
Proof-of-concept study of monitoring cancer drug therapy with cerenkov luminescence imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 22241909	2012
Human serum albumin conjugated biomolecules for cancer molecular imaging. Current pharmaceutical design\| PubMed ID: 22272822	2012
Biomarkers of endothelial dysfunction in patients with primary focal segmental glomerulosclerosis. Nephrology (Carlton, Vic.)\| PubMed ID: 22295953	2012
Analysis of in situ and ex vivo Î±VÎ²3 integrin expression during experimental carotid atherogenesis. International journal of nanomedicine\| PubMed ID: 22334786	2012
[Professor CHENG Zhifan and PUMHS Department of Medical History]. Zhonghua yi shi za zhi (Beijing, China : 1980)\| PubMed ID: 22335850	2011
A multimodality reporter gene for monitoring transplanted stem cells. Nuclear medicine and biology\| PubMed ID: 22336371	2012
A label-free G-quadruplex-based switch-on fluorescence assay for the selective detection of ATP. The Analyst\| PubMed ID: 22343772	2012
177Lu-DO3A-HSA-Z EGFR:1907: characterization as a potential radiopharmaceutical for radionuclide therapy of EGFR-expressing head and neck carcinomas. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry\| PubMed ID: 22418921	2012
In Vivo Biodistribution and Small Animal PET of (64)Cu-Labeled Antimicrobial Peptoids. Bioconjugate chemistry\| PubMed ID: 22486390	2012
111In-labeled cystine-knot peptides based on the Agouti-related protein for targeting tumor angiogenesis. Journal of biomedicine & biotechnology\| PubMed ID: 22570527	2012
The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles. Biomaterials\| PubMed ID: 22575830	2012
Evaluation of Four Affibody-Based Near-Infrared Fluorescent Probes for Optical Imaging of Epidermal Growth Factor Receptor Positive Tumors. Bioconjugate chemistry\| PubMed ID: 22621238	2012
Assessment and comparison of magnetic nanoparticles as MRI contrast agents in a rodent model of human hepatocellular carcinoma. Contrast media & molecular imaging\| PubMed ID: 22649042	2012
PET of EGFR expression with an 18F-labeled affibody molecule. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 22689926	2012
Discovery of a natural product inhibitor targeting protein neddylation by structure-based virtual screening. Biochimie\| PubMed ID: 22709868	2012
Radioluminescent nanophosphors enable multiplexed small-animal imaging. Optics express\| PubMed ID: 22714145	2012
Endoscopic imaging of Cerenkov luminescence. Biomedical optics express\| PubMed ID: 22741069	2012
A metal-based inhibitor of tumor necrosis factor-Î±. Angewandte Chemie (International ed. in English)\| PubMed ID: 22807261	2012
Activatable near-infrared fluorescent probe for in vivo imaging of fibroblast activation protein-alpha. Bioconjugate chemistry\| PubMed ID: 22812530	2012
Intraoperative imaging of tumors using cerenkov luminescence endoscopy: a feasibility experimental study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 22904353	2012
A novel radiofluorinated agouti-related protein for tumor angiogenesis imaging. Amino acids\| PubMed ID: 22945905	2012
Structural characterization of synthetic polymers using thermal-assisted atmospheric pressure glow discharge mass spectrometry. The Analyst\| PubMed ID: 22973573	2012
Novel, Cysteine-Modified Chelation Strategy for the Incorporation of [M(I)(CO)(3)](+) (M = Re, (99m)Tc) in an Î±-MSH Peptide. Bioconjugate chemistry\| PubMed ID: 23110503	2012
Continuous sensing of tumor-targeted molecular probes with a vertical cavity surface emitting laser-based biosensor. Journal of biomedical optics\| PubMed ID: 23123976	2012