Jason W. Rausch

RT Biochemistry Section, Frederick National Laboratory for Cancer Research

Affiliated withFrederick National Laboratory for Cancer Research

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 15	2013

Other Publications

Article	Year
Altering the RNase H primer grip of human immunodeficiency virus reverse transcriptase modifies cleavage specificity. Biochemistry\| PubMed ID: 11939780	2002
Mutations in the ribonuclease H active site of HIV-RT reveal a role for this site in stabilizing enzyme-primer-template binding. Biochemistry\| PubMed ID: 12206668	2002
Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12972638	2003
Using pyrrolo-deoxycytosine to probe RNA/DNA hybrids containing the human immunodeficiency virus type-1 3' polypurine tract. Nucleic acids research\| PubMed ID: 15004241	2004
'Binding, bending and bonding': polypurine tract-primed initiation of plus-strand DNA synthesis in human immunodeficiency virus. The international journal of biochemistry & cell biology\| PubMed ID: 15183342	2004
Purine analog substitution of the HIV-1 polypurine tract primer defines regions controlling initiation of plus-strand DNA synthesis. Nucleic acids research\| PubMed ID: 17164285	2007
Exploiting structurally diverse nucleoside analogs as probes of reverse transcription complexes. Current HIV research\| PubMed ID: 17266554	2007
Structural probing of the HIV-1 polypurine tract RNA:DNA hybrid using classic nucleic acid ligands. Nucleic acids research\| PubMed ID: 18400780	2008
Dynamic binding orientations direct activity of HIV reverse transcriptase. Nature\| PubMed ID: 18464735	2008
Slide into action: dynamic shuttling of HIV reverse transcriptase on nucleic acid substrates. Science (New York, N.Y.)\| PubMed ID: 19008444	2008
Dissecting APOBEC3G substrate specificity by nucleoside analog interference. The Journal of biological chemistry\| PubMed ID: 19136562	2009
Reverse transcriptase in motion: conformational dynamics of enzyme-substrate interactions. Biochimica et biophysica acta\| PubMed ID: 19665597	2010
HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) is regulated by determinants in the carbohydrate recognition domain that are absent in liver/lymph node-SI... The Journal of biological chemistry\| PubMed ID: 19833723	2010
Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H. Antimicrobial agents and chemotherapy\| PubMed ID: 20547794	2010
Synthesis, activity, and structural analysis of novel Î±-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H. Journal of medicinal chemistry\| PubMed ID: 21568335	2011
Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid. Nucleic acids research\| PubMed ID: 23382176	2013
Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome. Nucleic acids research\| PubMed ID: 23531545	2013
The HIV-2 Rev-response element: determining secondary structure and defining folding intermediates. Nucleic acids research\| PubMed ID: 23640333	2013