motor-imagery-brain-computer-interface-rehabilitation-upper-limb

Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke

The rehabilitation effect of patients with moderate or severe upper limb motor dysfunction after stroke is poor, which has been the focus of research ...

Guangzhou Medical University

the Fifth Affiliated Hospital of Guangzhou Medical University

Hepatocellular carcinoma (HCC) is a common cancer and the leading cause is persistent hepatitis B virus (HBV) infection. We aimed to identify some core genes and pathways for HBV-related HCC.

Identification and validation of three core genes in p53 signaling pathway in hepatitis B virus-related hepatocellular carcinoma.

Mirror visual feedback (MVF) has been widely used in neurological rehabilitation. Due to the potential gain effect of the MVF combination therapy, the related mechanisms still need be further analyzed.

Synergistic Immediate Cortical Activation on Mirror Visual Feedback Combined With a Soft Robotic Bilateral Hand Rehabilitation System: A Functional Near Infrared Spectroscopy Study.

Gastric cancer (GC) is a prevalent malignancy worldwide.  (PD), a traditional Chinese medicine formula, can treat inflammatory bowel disease and cancers. In this study, we explored the bioactive components, potential targets, and molecular mechanisms of PD in the treatment of GC.

Determining the mechanism of pulsatilla decoction for treating gastric cancer: a network pharmacology-based study.

With increasing occupational demands for flexed elbow postures, understanding multi-joint influences on upper limb musculature becomes crucial. ​This cross-sectional observational study investigated the effects of forearm rotation and elbow flexion angles on muscle stiffness and activation patterns in biceps brachii (BB) and brachioradialis (BR) during loaded isometric contractions.

Forearm rotation and elbow angle differentially modulate biceps brachii and brachioradialis muscle stiffness and EMG activity during low-load isometric contractions: a cross-sectional study in healthy individuals.

Gait analysis has emerged as a critical non-invasive tool for early identification and monitoring of mild cognitive impairment (MCI) in aging populations, particularly given its potential to predict dementia progression. This bibliometric analysis synthesizes two decades of research to map the evolution of gait analysis in MCI, identify interdisciplinary collaborations, and highlight emerging frontiers in MCI-related mobility research.

Gait analysis in older adults with mild cognitive impairment: a bibliometric analysis of global trends, hotspots, and emerging frontiers.

Although China has a vast population, less attention has been paid to the status and training needs of informal caregivers. This study aimed to assess the training needs of the informal caregivers in Jiangmen city, located in Guangdong Province in southern China.

Factors influencing the informal caregiving needs among the older adult population in Jiangmen City, China: a cross-sectional study.

β-hemoglobinopathies, such as sickle cell disease and β-thalassemia, are common genetic disorders remaining significant global health challenges due to their associated morbidity and mortality. Increasing fetal hemoglobin (HbF) levels has emerged as a promising therapeutic strategy for these disorders. In this study, we report Myc-associated zinc finger (MAZ) as an indirect repressor of γ-globin (HBG) expression in human erythroid cells. Depletion of MAZ in HUDEP-2 and patient-derived β-thalassemia cells leads to significant inductions of both HBG mRNA and protein levels, resulting in increased HbF percentages and HbF + erythroid cells. We demonstrate that MAZ occupies at the promoter of MYB, a well-known HBG repressor. MAZ depletion reduced MYB levels. Restoration of MYB re-silenced the HBG levels in MAZ depleted cells. Our findings uncover the MAZ-MYB axis in HBG regulation, highlighting MAZ as a potential target to enhance HbF levels in patients with hemoglobin disorders.

Article	Year
Identification and validation of three core genes in p53 signaling pathway in hepatitis B virus-related hepatocellular carcinoma. World journal of surgical oncology\| PubMed ID: 33685467	2021
Synergistic Immediate Cortical Activation on Mirror Visual Feedback Combined With a Soft Robotic Bilateral Hand Rehabilitation System: A Functional Near Infrared Spectroscopy Study. Frontiers in neuroscience\| PubMed ID: 35185457	2022
Determining the mechanism of pulsatilla decoction for treating gastric cancer: a network pharmacology-based study. Frontiers in oncology\| PubMed ID: 37361599	2023
Forearm rotation and elbow angle differentially modulate biceps brachii and brachioradialis muscle stiffness and EMG activity during low-load isometric contractions: a cross-sectional study ... BMC sports science, medicine & rehabilitation\| PubMed ID: 40604986	2025
Gait analysis in older adults with mild cognitive impairment: a bibliometric analysis of global trends, hotspots, and emerging frontiers. Frontiers in aging\| PubMed ID: 40612530	2025
Factors influencing the informal caregiving needs among the older adult population in Jiangmen City, China: a cross-sectional study. Frontiers in public health\| PubMed ID: 40977781	2025
MAZ regulates fetal hemoglobin repression by activating MYB transcription. Scientific reports\| PubMed ID: 41331317	2025

Siqi Huang

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