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Tri-Stream Disentangled Network with Adaptive Dual-Space Fusion for Electroencephalography-Based Image Reconstruction on THINGS-EEG2

Reconstructing visual stimuli from non-invasive electroencephalography (EEG) requires mapping short, noisy neural responses to meaningful visual ...

Beijing Technology and Business University

Conventional metasurface holograms relying on metal antennas for phase manipulation suffer from strong Ohmic loss and incomplete polarization conversion. The efficiency is limited to rather small values when operating in transmission mode. Here, we implement a high-efficiency transmissive metasurface hologram by leveraging the recently developed Huygens' metasurface to construct an electric and magnetic sheet with a transmission efficiency up to 86% and optical efficiency of 23.6%. The high-efficiency originates from the simultaneous excitations of the Mie-type electric and magnetic dipole resonances in the meta-atoms composed of silicon nanodisks. Our hologram shows high fidelity over a wide spectral range and promises to be an outstanding alternative for display applications.

Dielectric Huygens' Metasurface for High-Efficiency Hologram Operating in Transmission Mode.

Pseudomonas aeruginosa is a ubiquitous pathogen that is the leading cause of chronic infections. Bacterial biofilm formation facilitates CF development and restricts the anti-bacterial potential of many current antibiotics. The capacity of P. aeruginosa to form biofilms and resist antibiotics is closely correlated with quorum sensing (QS). Disrupting QS by QS inhibitors is a promising strategy for treating chronic infections. Here, we evaluated the effect of hordenine, a recently characterized QS inhibitor, on the susceptibility of aminoglycoside antibiotics against P. aeruginosa biofilms. Hordenine significantly enhanced the susceptibility of aminoglycoside antibiotics tobramycin, gentamycin, and amikacin against P. aeruginosa PAO1 biofilm formation. Combinations of hordenine and aminoglycoside antibiotics showed potent efficiency in disrupting the preformed biofilms of P. aeruginosa. Microscopic observations showed flat, scattered, and unstructured biofilm architecture after treatment with hordenine. Mechanistic study further revealed that hordenine treatment led to the downregulation of genes involved in QS and biofilm formation. Thus, our results suggest that hordenine has the potential to function as an antibiotic accelerant in treating P. aeruginosa infections.

Article	Year
Dielectric Huygens' Metasurface for High-Efficiency Hologram Operating in Transmission Mode. Scientific reports\| PubMed ID: 27457708	2016
Attenuation of Pseudomonas aeruginosa biofilm by hordenine: a combinatorial study with aminoglycoside antibiotics. Applied microbiology and biotechnology\| PubMed ID: 30128579	2018

Huan Jiang

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