mir-181b-5p-is-upregulated-first-episode-drug-naive-schizophrenia

miR-181b-5p is Upregulated in First-Episode Drug-Naive Schizophrenia and Correlates with Symptom Severity and Cognitive Deficits: A Case-Control Study

This study aimed to explore miR-181b-5p&#39;s diagnostic value in schizophrenia, analyze its correlations with symptoms and cognition, and evaluate ...

Qinhuangdao Fifth Hospital

The aim of the present study was to investigate a new clinical classification of cubital tunnel syndrome that provides an improved basis for the clinical diagnosis and treatment of the disease. Retrospective analysis was performed on 341 patients with cubital tunnel syndrome. Based on the etiology, signs and symptoms, neurophysiological tests and computed tomography (CT) imaging, a new clinical classification was proposed. The patients enrolled in the study were treated according to the new classification. According to the new classification, cubital tunnel syndrome cases were divided into types I-IV. Treatment for patients with type I consisted of rest, immobilization or physiotherapy, while patients with type II received simple ulnar neurolysis. Type III patients underwent ulnar neurolysis with expansion of the ulnar nerve sulcus or ulnar nerve anterior transposition surgery. Type IV patients represented a subgroup of cubital tunnel syndrome cases caused by factors other than degenerative joint diseases, including cysts, tumors, traumatic fracture, deformity and elbow deformity. Patients of this type received appropriate surgical treatment according to the specific etiology. Based on previous classifications that relied on sensation and strength symptoms, a new clinical classification of elbow tunnel syndrome has been established in the present study that adopts a CT imaging evaluation index. The new classification is reasonable, simple and practical, and therapies based on this classification are more targeted than those based on previous classifications.

Clinical classification and treatment of cubital tunnel syndrome.

Intramedullary fixation is a valuable alternative for the treatment of intertrochanteric fractures. However, further development of new biomarkers to predict the prognosis of the patient is still needed for timely and effective treatment and intervention. The present study aimed to explore the serum high-mobility group box 1 (HMGB1) levels in the prognosis of intertrochanteric fracture patients and its correlation with clinical results.

Article	Year
Clinical classification and treatment of cubital tunnel syndrome. Experimental and therapeutic medicine\| PubMed ID: 25289024	2014
Serum HMGB1 levels and its clinical significance in elderly patients with intertrochanteric fractures after intramedullary fixation surgery. Medicine\| PubMed ID: 36827030	2023

Haoran Li

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