a-flow-cytometry-based-method-for-profiling-immune-cells-human-blood

A Flow Cytometry-Based Method for Profiling Immune Cells in Human Blood and Tumors

Flow cytometry enables the simultaneous characterization of multiple immune-cell populations and their phenotypic subsets in clinical specimens. However, ...

Luoyang Central Hospital Affiliated to Zhengzhou University

To investigate the influence of length of preserved ileocecum on the efficacy of laparoscopic subtotal colectomy antiperistaltic cecorectal anastomosis (LSCACRA) in treating slow transit constipation (STC).

[Influence of length of preserved ileocecum on the efficacy of laparoscopic subtotal colectomy antiperistaltic cecorectal anastomosis in the treatment of slow transit constipation].

Slow transit constipation (STC) is the most common type of chronic constipation, and surgical treatment is one of the most important means for the treatment of slow transit constipation. With the introduction of the concept of STC and the normalization of STC treatment, development of surgical treatment in slow transit constipation is continuous, and the innovation of the operation method in slow transit constipation is continuous as well from partial colectomy, total colectomy (including ileorectal anastomosis, anorectal anastomosis and ileum bag anal canal anastomosis) to subtotal colectomy (including ileosigmoid colon anastomosis, isoperistaltic cecum rectal anastomosis and antiperistaltic cecum rectal anastomosis). Among these procedures, total colectomy ileorectal anastomosis is the ideal surgical procedure for the treatment of STC. Recent studies revealed that subtotal colectomy cecum rectal anastomosis could also achieve good efficacy. In addition, the other procedures for the treatment of STC include ileostomy, anterograde colonic lavage and colon exclusion, but it is necessary to strictly grasp the indications. With the development of minimally invasive technology, the application of laparoscopic technology in STC has been emphasized gradually. In general, the operation method has experienced from simple to complex and individual choice; from single surgical approach to multiple surgical methods; from abdominal open surgery to laparoscopic minimally invasive surgery. Relieving constipation symptoms and reducing the incidence of complications is the goal of surgical treatment that has always been the pursuit of STC surgery. The surgical method with good efficacy, small trauma, quick recovery and less complications must be designed to meet the individualized needs of patients with different constipations. In this paper, the efficacy and progress of surgical treatment of slow transit constipation from the generation and development are reviewed.

[Progress in the treatment of surgical procedures for slow transit constipation].

The spatial patterns of adverse pregnancy outcomes (APOs) are complex, vary by place, and remain not entirely clear. This study investigated spatiotemporal patterns of APOs in rural areas of Henan, China. We used data from 1,315,327 singleton pregnancies during 2013-2016 in rural areas of Henan, China, from the National Free Pre-pregnancy Checkup Program (NFPCP). A spatiotemporal analysis of APOs was conducted based on the time of conception and current address. Results of seasonality decomposed showed a slight decline in the incidence rate of APOs (12.93% to 11.27% in the compound trend) among the participants from 2013 to 2016 and also variation in annual periodicity (peaking in autumn at 12.66% and hitting bottom in spring at 11.16%). Spatial clusters of APOs were concentrated in an intersection band of northwestern to southeastern Henan Province (with a relative risk ratio ranging from 3.66 to 1.20), the northwestern and northern portion for temporal variation (having a trend in the cluster ranged from -6.25% to 83.93). This study provides an overall picture of APOs that presented downward trends over time, seasonal fluctuation, and clustered patterns across space and over time in Henan Province-the most populated province in China. The findings of this study warrant future studies to investigate underlying influential factors of spatial variation of APOs.

Spatiotemporal Patterns of Adverse Pregnancy Outcomes in Rural Areas of Henan, China.

Colorectal cancer (CRC) is among the leading causes of cancer-related mortality worldwide. This study aimed to assess the global burden of CRC across 204 countries and territories from 1990 to 2021, and identify its attributable risk factors.

The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for the global burden of disease study 2021.

Humidity and temperature may pose joint effects on human health. However, current temperature-related risk assessments generally focus on univariate temperature statistics, leading to inaccurate risk estimation. By combining temperature and humidity intensities as compound temperature-humidity events (hereinafter as compound events), we examined the effects of humidity in temperature-related health risks in the context of climate change in China using ambulance dispatch data, and further determined the high-risk types and thresholds of compound events. After assessing the health risks, compound events are defined as: i) warm and wet event: temperature ≥ 90th, humidity ≥ 55th and 70%; ii) warm and dry event: temperature ≥ 80th, humidity ≤ 10th; iii) cold and wet event: temperature ≤ 15th, humidity ≥ 70th and 70%; iv) cold and dry event: temperature ≤ 5th and humidity ≤ 25th. Results reveal that humidity can amplify the temperature-related health risks. Higher risks were found during cold and dry events and warm and wet events, posing risks as 1.102 (1.045–1.161) and 1.093 (1.068–1.118) respectively. Compound events mainly occurred in Southeast China during 1979–2019, while the frequency and gripped regions are projected to increase by 2100, and climate change will amplify these trends. Since humidity would exacerbate temperature-related health risks, therefore multiple meteorological parameters are needed in defining adverse weather conditions and conducting risk assessment accurately.

Article	Year
[Influence of length of preserved ileocecum on the efficacy of laparoscopic subtotal colectomy antiperistaltic cecorectal anastomosis in the treatment of slow transit constipation]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery\| PubMed ID: 26013863	2015
[Progress in the treatment of surgical procedures for slow transit constipation]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery\| PubMed ID: 29577225	2018
Spatiotemporal Patterns of Adverse Pregnancy Outcomes in Rural Areas of Henan, China. International journal of environmental research and public health\| PubMed ID: 36498035	2022
The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for the global burden of d... Frontiers in oncology\| PubMed ID: 41347078	2025
Humidity may amplify the temperature-related health risks in the context of climate change. Scientific reports\| PubMed ID: 41992004	2026

Dong Wei

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