visualized-empowerment-nursing-pathway-for-nutritional-outcomes

Visualized Empowerment Nursing Pathway for Nutritional Outcomes in Lymphoma with Chemotherapy-Induced Oral Mucositis: A Retrospective Cohort Study

This study examined the effect of an empowerment nursing model on the nutritional status of patients with lymphoma who developed oral mucositis during ...

Shanxi Provincial People's Hospital

Bruton's tyrosine kinase inhibitors (BTKi) exhibit superior efficacy in relapsed/refractory primary central nervous system lymphoma (PCNSL), but few studies have evaluated patients with newly diagnosed PCNSL, and even fewer studies have evaluated differences in efficacy between treatment with BTKi and traditional chemotherapy. This study retrospectively analyzed the clinical characteristics of 86 patients with PCNSL and identified predictors of poor prognosis for overall survival (OS). After excluding patients who only received palliative care, 82 patients were evaluated for efficacy and survival. According to the induction regimen, patients were divided into the traditional chemotherapy, BTKi combination therapy, and radiotherapy groups; the objective response rates (ORR) of the three groups were 71.4%, 96.2%, and 71.4% (P = 0.037), respectively. Both median progression-free survival and median duration of remission showed statistically significant differences (P = 0.019 and P = 0.030, respectively). The median OS of the BTKi-containing therapy group was also longer than that of the traditional chemotherapy group (not reached versus 47.8 (32.5-63.1) months, P = 0.038).Seventy-one patients who achieved an ORR were further analyzed, and achieved an ORR after four cycles of treatment and maintenance therapy had prolonged OS (P = 0.003 and P = 0.043, respectively). In conclusion, survival, and prognosis of patients with newly diagnosed PCNSL are influenced by the treatment regimen, with the BTKi-containing regimen showing great potential.

Clinical characteristics and prognosis of patients with newly diagnosed primary central nervous system lymphoma: a multicentre retrospective analysis.

Central nervous system involvement in chronic lymphocytic leukemia rarely occurs, and there is no standard therapy for central nervous system involvement in chronic lymphocytic leukemia. This article aims to analyze the diagnosis and treatment of central nervous system involvement in chronic lymphocytic leukemia.

Central nervous system involvement in chronic lymphocytic leukemia: a case report and review of literature.

The operating room environment demands high levels of teamwork and interprofessional collaboration, yet current training programs often lack sufficient opportunities to develop these essential skills. Few studies have explored the impact of Interprofessional Education (IPE) based on digital information technology in improving the collaboration and learning among newly enrolled medical staff in the operating room.

Research on the application effect of inter-professional training program for newly enrolled medical staff in operating room based on digital information technology.

Article	Year
Clinical characteristics and prognosis of patients with newly diagnosed primary central nervous system lymphoma: a multicentre retrospective analysis. Annals of hematology\| PubMed ID: 38761184	2024
Central nervous system involvement in chronic lymphocytic leukemia: a case report and review of literature. Journal of medical case reports\| PubMed ID: 38982482	2024
Research on the application effect of inter-professional training program for newly enrolled medical staff in operating room based on digital information technology. BMC medical education\| PubMed ID: 39543532	2024

Wenjun Wang

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