Dan S. Kaufman

Department of Medicine (Hematology, University of Minnesota, Minneapolis

Affiliated withUniversity of Minnesota, Minneapolis University of California, San Diego

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 45	2013
Publication title Cited by 2	2025

Other Publications

Article	Year
Differentiation of embryonic stem cells towards hematopoietic cells: progress and pitfalls. Current opinion in hematology\| PubMed ID: 18536568	2008
Differences in lymphocyte developmental potential between human embryonic stem cell and umbilical cord blood-derived hematopoietic progenitor cells. Blood\| PubMed ID: 18621931	2008
Functional endothelial cells derived from rhesus monkey embryonic stem cells. Blood\| PubMed ID: 14563647	2004
Mouse and human embryonic stem cell models of hematopoiesis: past, present, and future. BioTechniques\| PubMed ID: 14682061	2003
Efficient transfection of embryonic and adult stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 15277699	2004
Hematopoietic development of human embryonic stem cells in culture. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 15361661	2005
Hematopoietic development of human embryonic stem cells in culture. Methods in molecular medicine\| PubMed ID: 15492412	2005
Cytokine requirements differ for stroma and embryoid body-mediated hematopoiesis from human embryonic stem cells. Experimental hematology\| PubMed ID: 15504555	2004
Synergistic use of adult and embryonic stem cells to study human hematopoiesis. Current opinion in biotechnology\| PubMed ID: 16095900	2005
Nonhuman primate embryonic stem cells as a preclinical model for hematopoietic and vascular repair. Experimental hematology\| PubMed ID: 16140145	2005
Human embryonic stem cell-derived NK cells acquire functional receptors and cytolytic activity. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16210613	2005
Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients. Blood\| PubMed ID: 16278307	2006
Differentiation of human embryonic stem cells into hematopoietic cells by coculture with human fetal liver cells recapitulates the globin switch that occurs early in development. Experimental hematology\| PubMed ID: 16338487	2005
Defined conditions for development of functional hepatic cells from human embryonic stem cells. Stem cells and development\| PubMed ID: 16433619	2005
Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity. Stem cells (Dayton, Ohio)\| PubMed ID: 16456127	2006
Improved development of human embryonic stem cell-derived embryoid bodies by stirred vessel cultivation. Biotechnology and bioengineering\| PubMed ID: 16547998	2006
Derivation of normal macrophages from human embryonic stem (hES) cells for applications in HIV gene therapy. Retrovirology\| PubMed ID: 16623949	2006
Donor cell leukemia: insight into cancer stem cells and the stem cell niche. Blood\| PubMed ID: 17132724	2007
Efficient and stable transgene expression in human embryonic stem cells using transposon-mediated gene transfer. Stem cells (Dayton, Ohio)\| PubMed ID: 17673526	2007
Wnt signaling promotes hematoendothelial cell development from human embryonic stem cells. Blood\| PubMed ID: 17875805	2008
Reduced-intensity allogeneic transplant in patients older than 55 years: unrelated umbilical cord blood is safe and effective for patients without a matched related donor. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 18275894	2008
Hematopoietic development of human embryonic stem cells in culture. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18370295	2008
Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells. Stem cells and development\| PubMed ID: 18447647	2008
Activation of hypoxic response in human embryonic stem cell-derived embryoid bodies. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 18535160	2008
Hematopoietic differentiation of human embryonic stem cells by cocultivation with stromal layers. Current protocols in stem cell biology\| PubMed ID: 18819084	2008
Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity. Blood\| PubMed ID: 19365083	2009
Myeloablative hematopoietic cell transplantation for acute lymphoblastic leukemia: analysis of graft sources and long-term outcome. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 19581540	2009
Toward clinical therapies using hematopoietic cells derived from human pluripotent stem cells. Blood\| PubMed ID: 19652198	2009
Bioluminescent imaging demonstrates that transplanted human embryonic stem cell-derived CD34(+) cells preferentially develop into endothelial cells. Stem cells (Dayton, Ohio)\| PubMed ID: 19711457	2009
Human embryonic stem cell-derived vascular progenitor cells capable of endothelial and smooth muscle cell function. Experimental hematology\| PubMed ID: 20067819	2010
Use of human embryonic stem cells to understand hematopoiesis and hematopoietic stem cell niche. Current stem cell research & therapy\| PubMed ID: 20214557	2010
Human embryonic stem cell-derived CD34+ cells function as MSC progenitor cells. Bone\| PubMed ID: 20601304	2010
Pluripotent stem cell-derived natural killer cells for cancer therapy. Translational research : the journal of laboratory and clinical medicine\| PubMed ID: 20801411	2010
HIF hits Wnt in the stem cell niche. Nature cell biology\| PubMed ID: 20885419	2010
Human pluripotent stem cells produce natural killer cells that mediate anti-HIV-1 activity by utilizing diverse cellular mechanisms. Journal of virology\| PubMed ID: 20962093	2011
Methotrexate supports in vivo selection of human embryonic stem cell derived-hematopoietic cells expressing dihydrofolate reductase. Bioengineered bugs\| PubMed ID: 21468213	2010
Induction of fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 21674605	2011
Extramedullary relapse of acute myelogenous leukemia after allogeneic hematopoietic stem cell transplantation: better prognosis than systemic relapse. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 21703975	2012
A fibrin patch-based enhanced delivery of human embryonic stem cell-derived vascular cell transplantation in a porcine model of postinfarction left ventricular remodeling. Stem cells (Dayton, Ohio)\| PubMed ID: 21732493	2011
A synthetic substrate to support early mesodermal differentiation of human embryonic stem cells. Biomaterials\| PubMed ID: 21821284	2011
In vivo evaluation of putative hematopoietic stem cells derived from human pluripotent stem cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21822894	2011
Targeting tumor-initiating cancer cells with dCD133KDEL shows impressive tumor reductions in a xenotransplant model of human head and neck cancer. Molecular cancer therapeutics\| PubMed ID: 21862685	2011
Concise review: Cord blood banking, transplantation and induced pluripotent stem cell: success and opportunities. Stem cells (Dayton, Ohio)\| PubMed ID: 22069231	2012
Erythroid-specific expression of Î²-globin from Sleeping Beauty-transduced human hematopoietic progenitor cells. PloS one\| PubMed ID: 22216176	2011
Bioenergetic and functional consequences of cellular therapy: activation of endogenous cardiovascular progenitor cells. Circulation research\| PubMed ID: 22723295	2012
Pluripotent stem cells and gene therapy. Translational research : the journal of laboratory and clinical medicine\| PubMed ID: 23353080	2013
Functional consequences of human induced pluripotent stem cell therapy: myocardial ATP turnover rate in the in vivo swine heart with postinfarction remodeling. Circulation\| PubMed ID: 23371930	2013
RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells. Blood\| PubMed ID: 23372166	2013
Engineered Human Embryonic Stem Cell-Derived Lymphocytes to Study In Vivo Trafficking and Immunotherapy. Stem cells and development\| PubMed ID: 23421330	2013
Tu-mor(e) blood cells from human pluripotent stem cells. Blood\| PubMed ID: 23429981	2013
Clinical-scale derivation of natural killer cells from human pluripotent stem cells for cancer therapy. Stem cells translational medicine\| PubMed ID: 23515118	2013
Mouse Xenograft Model for Intraperitoneal Administration of NK Cell Immunotherapy for Ovarian Cancer. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27177674	2016
Fibrinogen Induces RUNX2 Activity and Osteogenic Development from Human Pluripotent Stem Cells. Stem cells (Dayton, Ohio)\| PubMed ID: 27331788	2016
Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent stem cells. Blood\| PubMed ID: 28533309	2017
Single Cell Resolution of Human Hematoendothelial Cells Defines Transcriptional Signatures of Hemogenic Endothelium. Stem cells (Dayton, Ohio)\| PubMed ID: 29139170	2018
Concise Review: Human Pluripotent Stem Cells to Produce Cell-Based Cancer Immunotherapy. Stem cells (Dayton, Ohio)\| PubMed ID: 29235195	2018
Advances in the role of the aryl hydrocarbon receptor to regulate early hematopoietic development. Current opinion in hematology\| PubMed ID: 29697485	2018
Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity. Cell stem cell\| PubMed ID: 30082067	2018
Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells. Seminars in immunopathology\| PubMed ID: 30361801	2019
Development of innate immune cells from human pluripotent stem cells. Experimental hematology\| PubMed ID: 30611869	2019
An Improved Method to Produce Clinical-Scale Natural Killer Cells from Human Pluripotent Stem Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 31396935	2019
Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity. Cell stem cell\| PubMed ID: 32531207	2020
Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis. Stem cells (Dayton, Ohio)\| PubMed ID: 34460131	2021
Into the multiverse of gene edited NK cell-based therapeutic strategies. Cell stem cell\| PubMed ID: 34861144	2021
Disease-associated mutations in topoisomerase IIβ result in defective NK cells. The Journal of allergy and clinical immunology\| PubMed ID: 35063500	2022
CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity. Nature communications\| PubMed ID: 35393416	2022
Engineered human pluripotent stem cell-derived natural killer cells: the next frontier for cancer immunotherapy. Blood science (Baltimore, Md.)\| PubMed ID: 35402797	2019
Induced pluripotent stem cell-derived engineered T cells, natural killer cells, macrophages, and dendritic cells in immunotherapy. Trends in biotechnology\| PubMed ID: 36858941	2023
CHMP2A regulates broad immune cell-mediated antitumor activity in an immunocompetent in vivo head and neck squamous cell carcinoma model. Journal for immunotherapy of cancer\| PubMed ID: 38702144	2024
Hemangiosarcoma Cells Promote Conserved Host-derived Hematopoietic Expansion. Cancer research communications\| PubMed ID: 38757809	2024
Disruption of TGF-β signaling pathway is required to mediate effective killing of hepatocellular carcinoma by human iPSC-derived NK cells. Cell stem cell\| PubMed ID: 38986609	2024
Next-generation macrophages: repolarizing CAR-macrophages against cancer. Blood science (Baltimore, Md.)\| PubMed ID: 39071949	2024