Richard Francis

Department of Developmental Biology, University of Pittsburgh

Affiliated withUniversity of Pittsburgh University of New South Wales Australia

Research Area

Biography

Richard Francis has not added Biography.
If you are Richard Francis and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 52	2013
Publication title Cited by 9	2016

Other Publications

Article	Year
Endothelin receptor A blockade ameliorates hypothermic ischemia-reperfusion-related microhemodynamic disturbances during liver transplantation in the rat. The Journal of surgical research\| PubMed ID: 11796000	2002
p107 and p130 Coordinately regulate proliferation, Cbfa1 expression, and hypertrophic differentiation during endochondral bone development. Developmental biology\| PubMed ID: 12086466	2002
Evaluation and management of scoliosis. Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners\| PubMed ID: 12533733	2003
Changes in activin and activin receptor subunit expression in rat liver during the development of CCl4-induced cirrhosis. Molecular and cellular endocrinology\| PubMed ID: 12706302	2003
Shared scheme for assessing drugs for multiple sclerosis: cost effective provision of effective treatments for multiple sclerosis. BMJ (Clinical research ed.)\| PubMed ID: 12775633	2003
Separation of immunoglobulin G precipitate from contaminating proteins using microfiltration. Biotechnology and applied biochemistry\| PubMed ID: 15032745	2004
Optimised affinity purification of polyclonal antibodies from hyper immunised ovine serum using a synthetic Protein A adsorbent, MAbsorbent A2P. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 15639441	2005
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells. The Journal of biological chemistry\| PubMed ID: 15741167	2005
Optimal conditions for the papain digestion of polyclonal ovine IgG for the production of bio-therapeutic Fab fragments. Biotechnology and applied biochemistry\| PubMed ID: 15799716	2005
Application of a decision-support tool to assess pooling strategies in perfusion culture processes under uncertainty. Biotechnology progress\| PubMed ID: 16080707	2005
From genome to vaccines for leishmaniasis: screening 100 novel vaccine candidates against murine Leishmania major infection. Vaccine\| PubMed ID: 16406227	2006
It's a puzzle all right: the hippocampus and food hoarding. Trends in ecology & evolution\| PubMed ID: 16701422	2005
The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells. The Journal of biological chemistry\| PubMed ID: 16809346	2006
Primordial germ cell deficiency in the connexin 43 knockout mouse arises from apoptosis associated with abnormal p53 activation. Development (Cambridge, England)\| PubMed ID: 16887824	2006
Connexin 43-mediated modulation of polarized cell movement and the directional migration of cardiac neural crest cells. Development (Cambridge, England)\| PubMed ID: 16914489	2006
The integrated simulation and assessment of the impacts of process change in biotherapeutic antibody production. Biotechnology progress\| PubMed ID: 17137309	2006
Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells. Molecular cancer\| PubMed ID: 17163992	2006
TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population. Diabetes\| PubMed ID: 17416797	2007
Multipotent hematopoietic cells susceptible to alternative double-strand break repair pathways that promote genome rearrangements. Genes & development\| PubMed ID: 17473170	2007
Detection and quantification of affinity ligand leaching and specific antibody fragment concentration within chromatographic fractions using surface plasmon resonance. Biotechnology and applied biochemistry\| PubMed ID: 17516918	2007
Decision-support software for the industrial-scale chromatographic purification of antibodies. Biotechnology progress\| PubMed ID: 17630695	2007
A prototype software methodology for the rapid evaluation of biomanufacturing process options. Biotechnology and applied biochemistry\| PubMed ID: 17868020	2007
Evolution of differences in transport function in Slc11a family members. The Journal of biological chemistry\| PubMed ID: 17932044	2007
Evaluation of a novel agarose-based synthetic ligand adsorbent for the recovery of antibodies from ovine serum. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 18024245	2007
Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia. The Journal of clinical investigation\| PubMed ID: 18037990	2007
Mouse model of heterotaxy with single ventricle spectrum of cardiac anomalies. Pediatric research\| PubMed ID: 18043505	2008
The transcription factor FOXO3a is a crucial cellular target of gefitinib (Iressa) in breast cancer cells. Molecular cancer therapeutics\| PubMed ID: 18089711	2007
Global Sensitivity Analysis for the determination of parameter importance in bio-manufacturing processes. Biotechnology and applied biochemistry\| PubMed ID: 18205624	2008
Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells. Molecular cancer therapeutics\| PubMed ID: 18347152	2008
The d subunit plays a central role in human vacuolar H(+)-ATPases. Journal of bioenergetics and biomembranes\| PubMed ID: 18752060	2008
Murine CENPF interacts with syntaxin 4 in the regulation of vesicular transport. Journal of cell science\| PubMed ID: 18827011	2008
Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19218456	2009
Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer. Molecular cancer therapeutics\| PubMed ID: 19276163	2009
Initiation and maturation of cilia-generated flow in newborn and postnatal mouse airway. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 19346437	2009
FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer. International journal of oncology\| PubMed ID: 19513552	2009
Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development. Development (Cambridge, England)\| PubMed ID: 19700622	2009
Ventricular rotation is independent of cardiac looping: a study in mice with situs inversus totalis using speckle-tracking echocardiography. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography\| PubMed ID: 20097527	2010
Armus is a Rac1 effector that inactivates Rab7 and regulates E-cadherin degradation. Current biology : CB\| PubMed ID: 20116244	2010
A screen for endocytic motifs. Traffic (Copenhagen, Denmark)\| PubMed ID: 20214754	2010
Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation. Blood\| PubMed ID: 20299509	2010
Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemia. BMC genomics\| PubMed ID: 20406497	2010
An automated packed protein G micro-pipette tip assay for rapid quantification of polyclonal antibodies in ovine serum. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 20951101	2010
Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome. Disease models & mechanisms\| PubMed ID: 21045211	2011
Classification and regression tree and spatial analyses reveal geographic heterogeneity in genome wide linkage study of Indian visceral leishmaniasis. PloS one\| PubMed ID: 21209823	2010
Predominance of nontypeable Haemophilus influenzae in children with otitis media following introduction of a 3+0 pneumococcal conjugate vaccine schedule. Vaccine\| PubMed ID: 21621576	2011
Comparison of post-treatment effects of conventional and acupuncture-like transcutaneous electrical nerve stimulation (TENS): A randomised placebo-controlled study using cold-induced pain an... Physiotherapy theory and practice\| PubMed ID: 21721994	2011
Genetic and functional evidence implicating DLL1 as the gene that influences susceptibility to visceral leishmaniasis at chromosome 6q27. The Journal of infectious diseases\| PubMed ID: 21742847	2011
Conventional versus acupuncture-like transcutaneous electrical nerve stimulation on cold-induced pain in healthy human participants: effects during stimulation. Clinical physiology and functional imaging\| PubMed ID: 21771255	2011
Comparison of post-treatment effects of conventional and acupuncture-like transcutaneous electrical nerve stimulation (TENS): A randomised placebo-controlled study using cold-induced pain an... Physiotherapy theory and practice\| PubMed ID: 22007892	2011
Transfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non-transferrin-bound iron. Blood\| PubMed ID: 22021369	2011
Connexin43 modulates cell polarity and directional cell migration by regulating microtubule dynamics. PloS one\| PubMed ID: 22022608	2011
Traumatic intracerebral hemorrhage--to operate or not? World neurosurgery\| PubMed ID: 22251488	2011
Congenital heart disease and the specification of left-right asymmetry. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 22408017	2012
Rapid detection of Klebsiella pneumoniae carbapenemase genes in enterobacteriaceae directly from blood culture bottles by real-time PCR. American journal of clinical pathology\| PubMed ID: 22431540	2012
The characteristics of acupuncture-like transcutaneous electrical nerve stimulation (acupuncture-like TENS): a literature review. Acupuncture & electro-therapeutics research\| PubMed ID: 22443026	2011
West Nile virus infection in blood donors in the New York City area during the 2010 seasonal epidemic. Transfusion\| PubMed ID: 22486471	2012
High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy. Circulation\| PubMed ID: 22499950	2012
Frequency of glucose-6-phosphate dehydrogenase-deficient red blood cell units in a metropolitan transfusion service. Transfusion\| PubMed ID: 22738400	2013
FusionFinder: a software tool to identify expressed gene fusion candidates from RNA-Seq data. PloS one\| PubMed ID: 22761941	2012
TENS (transcutaneous electrical nerve stimulation) for labour pain. The practising midwife\| PubMed ID: 22788003	2012
Acquired hemoglobin variants and exposure to glucose-6-phosphate dehydrogenase deficient red blood cell units during exchange transfusion for sickle cell disease in a patient requiring antig... Journal of clinical apheresis\| PubMed ID: 23450789	2013
Genetic and functional evidence for a role for SLC11A1 in susceptibility to otitis media in early childhood in a Western Australian population. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases\| PubMed ID: 23538334	2013
The TBC/RabGAP Armus coordinates Rac1 and Rab7 functions during autophagy. Developmental cell\| PubMed ID: 23562278	2013
The International Collaboration for Autism Registry Epidemiology (iCARE): Multinational Registry-Based Investigations of Autism Risk Factors and Trends. Journal of autism and developmental disorders\| PubMed ID: 23563868	2013
Strain-specific red blood cell storage, metabolism, and eicosanoid generation in a mouse model. Transfusion\| PubMed ID: 23721209	2013
Microcomputed tomography provides high accuracy congenital heart disease diagnosis in neonatal and fetal mice. Circulation. Cardiovascular imaging\| PubMed ID: 23759365	2013
ARMC4 Mutations Cause Primary Ciliary Dyskinesia with Randomization of Left/Right Body Asymmetry. American journal of human genetics\| PubMed ID: 23849778	2013
The ability of an arginine to tryptophan substitution in Saccharomyces cerevisiae tRNA nucleotidyltransferase to alleviate a temperature-sensitive phenotype suggests a role for motif C in ac... Biochimica et biophysica acta\| PubMed ID: 23872483	2013
DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nature genetics\| PubMed ID: 23872636	2013
Increased postoperative respiratory complications in heterotaxy congenital heart disease patients with respiratory ciliary dysfunction. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 23886032	2013
Imaging techniques for visualizing and phenotyping congenital heart defects in murine models. Birth defects research. Part C, Embryo today : reviews\| PubMed ID: 23897594	2013
Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS biology\| PubMed ID: 24302887	2013
Ion Torrent sequencing for conducting genome-wide scans for mutation mapping analysis. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 24306492	2014
Interrogating congenital heart defects with noninvasive fetal echocardiography in a mouse forward genetic screen. Circulation. Cardiovascular imaging\| PubMed ID: 24319090	2014
Attitudes to intracranial pressure monitoring of traumatic intracerebral haemorrhage. British journal of neurosurgery\| PubMed ID: 24479704	2014
Genetic and functional evidence for a locus controlling otitis media at chromosome 10q26.3. BMC medical genetics\| PubMed ID: 24499112	2014
GOLink: Finding Cooccurring Terms across Gene Ontology Namespaces. International journal of genomics\| PubMed ID: 24524070	2013
A comparison of adverse reaction rates for PAS C versus plasma platelet units. Transfusion\| PubMed ID: 24735171	2014
Transfusion of stored blood impairs host defenses against Gram-negative pathogens in mice. Transfusion\| PubMed ID: 24840185	2014
Decellularized tracheal extracellular matrix supports epithelial migration, differentiation, and function. Tissue engineering. Part A\| PubMed ID: 24980864	2015
Macrophages clear refrigerator storage-damaged red blood cells and subsequently secrete cytokines in vivo, but not in vitro, in a murine model. Transfusion\| PubMed ID: 25041478	2014
Methaemoglobinaemia and haemolysis following pegloticase infusion for refractory gout in a patient with a falsely negative glucose-6-phosphate dehydrogenase deficiency result. Rheumatology (Oxford, England)\| PubMed ID: 25224415	2014
DataSHIELD: taking the analysis to the data, not the data to the analysis. International journal of epidemiology\| PubMed ID: 25261970	2014
Marine geophysics. New global marine gravity model from CryoSat-2 and Jason-1 reveals buried tectonic structure. Science (New York, N.Y.)\| PubMed ID: 25278606	2014
Airway ciliary dysfunction and sinopulmonary symptoms in patients with congenital heart disease. Annals of the American Thoracic Society\| PubMed ID: 25302410	2014
The effects of temperature and anesthetic agents on ciliary function in murine respiratory epithelia. Frontiers in pediatrics\| PubMed ID: 25360434	2014
IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment. Developmental cell\| PubMed ID: 25446516	2014
ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning. Nature communications\| PubMed ID: 25599650	2015
Dexmedetomidine and fentanyl exhibit temperature dependent effects on human respiratory cilia. Frontiers in pediatrics\| PubMed ID: 25717467	2015
Early Surgery versus Initial Conservative Treatment in Patients with Traumatic Intracerebral Hemorrhage (STITCH[Trauma]): The First Randomized Trial. Journal of neurotrauma\| PubMed ID: 25738794	2015
First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes. PloS one\| PubMed ID: 25760438	2015
Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature\| PubMed ID: 25807483	2015
Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies. Human molecular genetics\| PubMed ID: 25877302	2015
The future of host cell protein (HCP) identification during process development and manufacturing linked to a risk-based management for their control. Biotechnology and bioengineering\| PubMed ID: 25998019	2015
Distribution of raphespinal fibers in the mouse spinal cord. Molecular pain\| PubMed ID: 26173454	2015
Red blood cell transfusion is associated with increased hemolysis and an acute phase response in a subset of critically ill children. American journal of hematology\| PubMed ID: 26183122	2015
G6PD Deficiency in an HIV Clinic Setting in the Dominican Republic. The American journal of tropical medicine and hygiene\| PubMed ID: 26240158	2015
Automated identification of abnormal respiratory ciliary motion in nasal biopsies. Science translational medicine\| PubMed ID: 26246169	2015
Surgical Trial In Traumatic intraCerebral Haemorrhage (STITCH): a randomised controlled trial of Early Surgery compared with Initial Conservative Treatment. Health technology assessment (Winchester, England)\| PubMed ID: 26346805	2015
Characteristics of traumatic intracerebral haemorrhage: An assessment of screening logs from the STITCH(Trauma) Trial. British journal of neurosurgery\| PubMed ID: 26414559	2015
Discovery of four recessive developmental disorders using probabilistic genotype and phenotype matching among 4,125 families. Nature genetics\| PubMed ID: 26437029	2015
ViPAR: a software platform for the Virtual Pooling and Analysis of Research Data. International journal of epidemiology\| PubMed ID: 26452388	2015
DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia. PLoS genetics\| PubMed ID: 26918822	2016
Reference genotype and exome data from an Australian Aboriginal population for health-based research. Scientific data\| PubMed ID: 27070114	2016
Diagnosis of a rare fetal haemoglobinopathy in the age of next-generation sequencing. BMJ case reports\| PubMed ID: 27095814	2016
Attitudes in 2013 to Monitoring Intracranial Pressure for Traumatic Intracerebral Haemorrhage. Acta neurochirurgica. Supplement\| PubMed ID: 27165869	2016
Red blood cell components: Meeting the quantitative and qualitative transfusion needs. Presse medicale (Paris, France : 1983)\| PubMed ID: 27476016	2016