Avi Gnatt

Department of Pharmacology & Experimental Therapeutics, University of Maryland School of Medicine

Affiliated withUniversity of Maryland School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2013

Other Publications

Article	Year
Intramolecular relationships in cholinesterases revealed by oocyte expression of site-directed and natural variants of human BCHE. The EMBO journal\| PubMed ID: 1373381	1992
Excavations into the active-site gorge of cholinesterases. Trends in biochemical sciences\| PubMed ID: 1412713	1992
Human acetylcholinesterase and butyrylcholinesterase are encoded by two distinct genes. Cellular and molecular neurobiology\| PubMed ID: 2013062	1991
Aspartate-70 to glycine substitution confers resistance to naturally occurring and synthetic anionic-site ligands on in-ovo produced human butyrylcholinesterase. Journal of neuroscience research\| PubMed ID: 2079709	1990
Anionic site interactions in human butyrylcholinesterase disrupted by two single point mutations. The Journal of biological chemistry\| PubMed ID: 2249982	1990
Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 2263619	1990
Expression of alternatively terminated unusual human butyrylcholinesterase messenger RNA transcripts, mapping to chromosome 3q26-ter, in nervous system tumors. Cancer research\| PubMed ID: 2317787	1990
Molecular cloning of human cholinesterase genes: potential applications in neurotoxicology. Progress in clinical and biological research\| PubMed ID: 2963345	1987
Isolation and characterization of full-length cDNA clones coding for cholinesterase from fetal human tissues. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 3035536	1987
Molecular biological search for human genes encoding cholinesterases. Molecular neurobiology\| PubMed ID: 3077058	1987
Use of synthetic oligodeoxynucleotide probes for the isolation of a human cholinesterase cDNA clone. Journal of neuroscience research\| PubMed ID: 3755763	1986
Testicular amplification and impaired transmission of human butyrylcholinesterase cDNA in transgenic mice. Human reproduction (Oxford, England)\| PubMed ID: 8027285	1994
Chimeric human cholinesterase. Identification of interaction sites responsible for recognition of acetyl- or butyrylcholinesterase-specific ligands. Journal of molecular biology\| PubMed ID: 8230213	1993
Structure-function relationship studies in human cholinesterases reveal genomic origins for individual variations in cholinergic drug responses. Progress in neuro-psychopharmacology & biological psychiatry\| PubMed ID: 8278601	1993
Site-directed mutagenesis of active site residues reveals plasticity of human butyrylcholinesterase in substrate and inhibitor interactions. Journal of neurochemistry\| PubMed ID: 8294937	1994
Evidence for a mediator cycle at the initiation of transcription. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 9177171	1997
Formation and crystallization of yeast RNA polymerase II elongation complexes. The Journal of biological chemistry\| PubMed ID: 9388221	1997
Repeated tertiary fold of RNA polymerase II and implications for DNA binding. Journal of molecular biology\| PubMed ID: 9665838	1998
Electron crystal structure of an RNA polymerase II transcription elongation complex. Cell\| PubMed ID: 10499796	1999
Yeast RNA polymerase II at 5 A resolution. Cell\| PubMed ID: 10499797	1999
Architecture of RNA polymerase II and implications for the transcription mechanism. Science (New York, N.Y.)\| PubMed ID: 10784442	2000
Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution. Science (New York, N.Y.)\| PubMed ID: 11313499	2001
Elongation by RNA polymerase II: structure-function relationship. Biochimica et biophysica acta\| PubMed ID: 12213651	2002
Cancer outcomes at the Hufeland (complementary/alternative medicine) klinik: a best-case series review. Integrative cancer therapies\| PubMed ID: 15911928	2005
Fcp1 directly recognizes the C-terminal domain (CTD) and interacts with a site on RNA polymerase II distinct from the CTD. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16301539	2005
A Mediator-responsive form of metazoan RNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16769904	2006
Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis. BMC cancer\| PubMed ID: 18474089	2008
Differential blocking effects of the acetaldehyde-derived DNA lesion N2-ethyl-2'-deoxyguanosine on transcription by multisubunit and single subunit RNA polymerases. The Journal of biological chemistry\| PubMed ID: 18669632	2008
Regulation of RUNX2 transcription factor-DNA interactions and cell proliferation by vitamin D3 (cholecalciferol) prohormone activity. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 22189971	2012
Functional association of Gdown1 with RNA polymerase II poised on human genes. Molecular cell\| PubMed ID: 22244331	2012
Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II. Molecular cell\| PubMed ID: 22244332	2012
Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II. Transcription\| PubMed ID: 22771949	2012
Regulation of mammalian transcription by Gdown1 through a novel steric crosstalk revealed by cryo-EM. The EMBO journal\| PubMed ID: 22850672	2012
Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides. PLoS pathogens\| PubMed ID: 23166498	2012