Jean-Marc Taymans

Laboratory for Neurobiology and Gene Therapy, KU Leuven and Leuven Institute for Neuroscience and Disease (LIND)

Affiliated withKU Leuven and Leuven Institute for Neuroscience and Disease (LIND)

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2013

Other Publications

Article	Year
The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation. PloS one\| PubMed ID: 20090955	2010
Neuroscience letters\| PubMed ID: 16154268	2006
Distribution of PINK1 and LRRK2 in rat and mouse brain. Journal of neurochemistry\| PubMed ID: 16771836	2006
Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain. Human gene therapy\| PubMed ID: 17343566	2007
The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation. The Journal of biological chemistry\| PubMed ID: 18397888	2008
The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites. Biochemical and biophysical research communications\| PubMed ID: 19733152	2009
Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19890007	2009
Mechanisms in dominant parkinsonism: The toxic triangle of LRRK2, alpha-synuclein, and tau. BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 20127702	2010
Inhibition of FK506 binding proteins reduces alpha-synuclein aggregation and Parkinson's disease-like pathology. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20164329	2010
Immunohistochemical detection of transgene expression in the brain using small epitope tags. BMC biotechnology\| PubMed ID: 20167102	2010
Automated quantitative gait analysis in animal models of movement disorders. BMC neuroscience\| PubMed ID: 20691122	2010
Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant. Journal of neurochemistry\| PubMed ID: 21073465	2011
Kinases as targets for Parkinson's disease: from genetics to therapy. CNS & neurological disorders drug targets\| PubMed ID: 21838679	2011
LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding. PloS one\| PubMed ID: 21858031	2011
Expression, purification and preliminary biochemical and structural characterization of the leucine rich repeat namesake domain of leucine rich repeat kinase 2. Biochimica et biophysica acta\| PubMed ID: 22251894	2012
Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers. PloS one\| PubMed ID: 22952686	2012
The GTPase function of LRRK2. Biochemical Society transactions\| PubMed ID: 22988866	2012
Phosphorylation of LRRK2: from kinase to substrate. Biochemical Society transactions\| PubMed ID: 22988873	2012
MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein. Human molecular genetics\| PubMed ID: 23125283	2013
Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle. The Biochemical journal\| PubMed ID: 23937259	2013