Alfred E. Chang

Department of Surgery, University of Michigan

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 15	2014

Other Publications

Article	Year
A phase I trial of tumor lysate-pulsed dendritic cells in the treatment of advanced cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 11948109	2002
Resection of liver tumors: technical aspects. Surgical oncology\| PubMed ID: 12020669	2002
Mammographic screening of TRAM flap breast reconstructions for detection of nonpalpable recurrent cancer. Radiology\| PubMed ID: 12091685	2002
Therapeutic effects of tumor reactive CD4+ cells generated from tumor-primed lymph nodes using anti-CD3/anti-CD28 monoclonal antibodies. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 12142553	2002
Hepatic artery chemotherapy for colorectal liver metastases: technical considerations and review of clinical trials. Surgical oncology\| PubMed ID: 12356508	2002
Melanoma and human leukocyte antigen status: the missing link? Annals of surgical oncology\| PubMed ID: 12374654	2002
Applications of gene transfer to cellular immunotherapy. Surgical oncology clinics of North America\| PubMed ID: 12487059	2002
Generation of vaccine-primed lymphocytes for the treatment of head and neck cancer. Head & neck\| PubMed ID: 12599287	2003
Phase II trial of autologous tumor vaccination, anti-CD3-activated vaccine-primed lymphocytes, and interleukin-2 in stage IV renal cell cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 12610189	2003
Polarization effects of 4-1BB during CD28 costimulation in generating tumor-reactive T cells for cancer immunotherapy. Cancer research\| PubMed ID: 12750278	2003
Antitumor reactivity of anti-CD3/anti-CD28 bead-activated lymphoid cells: implications for cell therapy in a murine model. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 12806276	2003
Sentinel node biopsy prior to neoadjuvant chemotherapy. American journal of surgery\| PubMed ID: 12885598	2003
Comparison of attenuation-corrected and non-corrected FDG-PET images for axillary nodal staging in newly diagnosed breast cancer. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 14537139	2002
Clinicopathologic features of metastasis in nonsentinel lymph nodes of breast carcinoma patients. Cancer\| PubMed ID: 14635063	2003
Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administration. Cancer research\| PubMed ID: 14679011	2003
Intratumoral IL-12 and TNF-alpha-loaded microspheres lead to regression of breast cancer and systemic antitumor immunity. Annals of surgical oncology\| PubMed ID: 14761917	2004
Exaggerated pigmented granulomatous reaction to the artificial joint implant mimics metastatic melanoma. Diagnostic cytopathology\| PubMed ID: 14986302	2004
Mitotic rate and younger age are predictors of sentinel lymph node positivity: lessons learned from the generation of a probabilistic model. Annals of surgical oncology\| PubMed ID: 14993019	2004
Donor cell cycling, trafficking, and accumulation during adoptive immunotherapy for murine lung metastases. Cancer research\| PubMed ID: 15026361	2004
Efficacy of sentinel lymph node biopsy in male breast cancer. Journal of surgical oncology\| PubMed ID: 15112248	2004
Mastectomy and concomitant sentinel lymph node biopsy for invasive breast cancer. American journal of surgery\| PubMed ID: 15191855	2004
An academic health center cost analysis of screening mammography: creating a financially viable service. Cancer\| PubMed ID: 15329914	2004
Anti-CD137 monoclonal antibody administration augments the antitumor efficacy of dendritic cell-based vaccines. Cancer research\| PubMed ID: 15548712	2004
Synergistic effects of IL-12 and IL-18 in skewing tumor-reactive T-cell responses towards a type 1 pattern. Cancer research\| PubMed ID: 15705908	2005
Immunologic response to cryoablation of breast cancer. Breast cancer research and treatment\| PubMed ID: 15770533	2005
Predictors of nonsentinel lymph node positivity in patients with a positive sentinel node for melanoma. Journal of the American College of Surgeons\| PubMed ID: 15978442	2005
Capecitabine and radiation therapy preceded and followed by combination chemotherapy in advanced pancreatic cancer. International journal of radiation oncology, biology, physics\| PubMed ID: 15993549	2005
Simultaneous targeting of CD3 on T cells and CD40 on B or dendritic cells augments the antitumor reactivity of tumor-primed lymph node cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16034078	2005
Is blue dye indicated for sentinel lymph node biopsy in breast cancer patients with a positive lymphoscintigram? Annals of surgical oncology\| PubMed ID: 16079955	2005
Comprehensive axillary evaluation in neoadjuvant chemotherapy patients with ultrasonography and sentinel lymph node biopsy. Annals of surgical oncology\| PubMed ID: 16079956	2005
Wide excision without radiation for desmoplastic melanoma. Cancer\| PubMed ID: 16080180	2005
Lymphatic mapping and sentinel lymph node biopsy for patients with local recurrence after breast-conservation therapy. Annals of surgical oncology\| PubMed ID: 16372155	2006
Clinicopathologic features associated with having four or more metastatic axillary nodes in breast cancer patients with a positive sentinel lymph node. Annals of surgical oncology\| PubMed ID: 16378156	2006
Does the method of biopsy affect the incidence of sentinel lymph node metastases? The breast journal\| PubMed ID: 16409587	2006
Ex vivo culture with interleukin (IL)-12 improves CD8(+) T-cell adoptive immunotherapy for murine leukemia independent of IL-18 or IFN-gamma but requires perforin. Cancer research\| PubMed ID: 16651448	2006
Significance of multiple lymphatic basin drainage in truncal melanoma patients undergoing sentinel lymph node biopsy. Annals of surgical oncology\| PubMed ID: 16952026	2006
Neoadjuvant intratumoral cytokine-loaded microspheres are superior to postoperative autologous cellular vaccines in generating systemic anti-tumor immunity. Journal of surgical oncology\| PubMed ID: 16967445	2006
Adoptive immunotherapy of breast cancer with lymph node cells primed by cryoablation of the primary tumor. Cryobiology\| PubMed ID: 16973145	2006
Changes in surgical management resulting from case review at a breast cancer multidisciplinary tumor board. Cancer\| PubMed ID: 16998942	2006
CXC chemokine ligand 13 and CC chemokine ligand 19 cooperatively render resistance to apoptosis in B cell lineage acute and chronic lymphocytic leukemia CD23+CD5+ B cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17082584	2006
The impact of factors beyond Breslow depth on predicting sentinel lymph node positivity in melanoma. Cancer\| PubMed ID: 17146784	2007
Improving surgical outcomes for cancer in the United States. Journal of surgical oncology\| PubMed ID: 17262738	2007
What is a sentinel node? Re-evaluating the 10% rule for sentinel lymph node biopsy in melanoma. Journal of surgical oncology\| PubMed ID: 17345610	2007
Radiation-induced apoptosis along with local and systemic cytokine elaboration is associated with DC plus radiotherapy-mediated renal cell tumor regression. Clinical immunology (Orlando, Fla.)\| PubMed ID: 17449328	2007
4-1BB costimulation of effector T cells for adoptive immunotherapy of cancer: involvement of Bcl gene family members. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 17457215	2007
Sentinel lymph node biopsy performed after neoadjuvant chemotherapy is accurate in patients with documented node-positive breast cancer at presentation. Annals of surgical oncology\| PubMed ID: 17514407	2007
Inguinal node dissection for melanoma in the era of sentinel lymph node biopsy. Surgery\| PubMed ID: 17560249	2007
Sentinel lymph node biopsy for breast cancer: how many nodes are enough? Journal of surgical oncology\| PubMed ID: 17685432	2007
CCL19 and CXCL13 synergistically regulate interaction between B cell acute lymphocytic leukemia CD23+CD5+ B Cells and CD8+ T cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17709502	2007
Phase I study of oxaliplatin, full-dose gemcitabine, and concurrent radiation therapy in pancreatic cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 17925553	2007
The registry case finding engine: an automated tool to identify cancer cases from unstructured, free-text pathology reports and clinical notes. Journal of the American College of Surgeons\| PubMed ID: 17964445	2007
Synergistic effect of intratumoral IL-12 and TNF-alpha microspheres: systemic anti-tumor immunity is mediated by both CD8+ CTL and NK cells. Surgery\| PubMed ID: 17981196	2007
Generation of a tumor-specific systemic response after intratumoral injection of IL-12 and IL-18-loaded polylactic acid microspheres. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 18049332	2007
Adjuvant effect of anti-4-1BB mAb administration in adoptive T cell therapy of cancer. International journal of biological sciences\| PubMed ID: 18071585	2007
Mechanisms involved in radiation enhancement of intratumoral dendritic cell therapy. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 18391761	2008
Interleukin-21 augments the efficacy of T-cell therapy by eliciting concurrent cellular and humoral responses. Cancer research\| PubMed ID: 18519706	2008
Phase Ib trial assessing autologous, tumor-pulsed dendritic cells as a vaccine administered with or without IL-2 in patients with metastatic melanoma. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 18528294	2008
Tumor-induced immune suppression of in vivo effector T-cell priming is mediated by the B7-H1/PD-1 axis and transforming growth factor beta. Cancer research\| PubMed ID: 18593946	2008
Do micromorphometric features of metastatic deposits within sentinel nodes predict nonsentinel lymph node involvement in melanoma? Annals of surgical oncology\| PubMed ID: 18626721	2008
Axillary staging prior to neoadjuvant chemotherapy for breast cancer: predictors of recurrence. Annals of surgical oncology\| PubMed ID: 18784961	2008
Intratumoral dendritic cells and chemoradiation for the treatment of murine squamous cell carcinoma. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 18832999	2008
Dendritic cells pulsed with keyhole limpet hemocyanin and cryopreserved maintain anti-tumor activity in a murine melanoma model. Clinical immunology (Orlando, Fla.)\| PubMed ID: 18845485	2008
Residual disease after re-excision lumpectomy for close margins. Journal of surgical oncology\| PubMed ID: 19065638	2009
Determinants of breast conservation rates: reasons for mastectomy at a comprehensive cancer center. The breast journal\| PubMed ID: 19141132	2009
Antitumor activity of T cells generated from lymph nodes draining the SEA-expressing murine B16 melanoma and secondarily activated with dendritic cells. International journal of biological sciences\| PubMed ID: 19173035	2009
Gemcitabine-based combination chemotherapy followed by radiation with capecitabine as adjuvant therapy for resected pancreas cancer. International journal of radiation oncology, biology, physics\| PubMed ID: 19409732	2009
Radiotherapy combined with intratumoral dendritic cell vaccination enhances the therapeutic efficacy of adoptive T-cell transfer. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 19483649	2009
In vivo sensitized and in vitro activated B cells mediate tumor regression in cancer adoptive immunotherapy. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19667089	2009
Prognostic significance of a positive nonsentinel lymph node in cutaneous melanoma. Annals of surgical oncology\| PubMed ID: 19711133	2009
Intratumoral delivery of encapsulated IL-12, IL-18 and TNF-alpha in a model of metastatic breast cancer. Breast cancer research and treatment\| PubMed ID: 19802695	2010
Is there a benefit to sentinel lymph node biopsy in patients with T4 melanoma? Cancer\| PubMed ID: 19827151	2009
Rate of freeze alters the immunologic response after cryoablation of breast cancer. Annals of surgical oncology\| PubMed ID: 20033323	2010
From the guest editors: introduction to local therapies in the treatment of liver cancer. Cancer journal (Sudbury, Mass.)\| PubMed ID: 20404604	2010
Intratumoral expression of IL-17 and its prognostic role in gastric adenocarcinoma patients. International journal of biological sciences\| PubMed ID: 21234303	2011
Surgical options for localized and advanced gastrointestinal stromal tumors. Journal of surgical oncology\| PubMed ID: 21381037	2011
Adoptive transfer of tumor reactive B cells confers host T-cell immunity and tumor regression. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21690573	2011
Long-term cultured human neural stem cells undergo spontaneous transformation to tumor-initiating cells. International journal of biological sciences\| PubMed ID: 21814484	2011
Validation of statistical predictive models meant to select melanoma patients for sentinel lymph node biopsy. Annals of surgical oncology\| PubMed ID: 21822550	2012
Is a level III dissection necessary for a positive sentinel lymph node in melanoma? Journal of surgical oncology\| PubMed ID: 21882199	2012
B lymphocytes as effector cells in the immunotherapy of cancer. Journal of surgical oncology\| PubMed ID: 21898417	2012
Defining the critical hurdles in cancer immunotherapy. Journal of translational medicine\| PubMed ID: 22168571	2011
Is duct excision still necessary for all cases of suspicious nipple discharge? The breast journal\| PubMed ID: 22211878	2012
Characterization of bridging integrator 1 (BIN1) as a potential tumor suppressor and prognostic marker in hepatocellular carcinoma. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 22281836	2012
Cancer stem cell vaccination confers significant antitumor immunity. Cancer research\| PubMed ID: 22473314	2012
Interleukin-6 inhibits regulatory T cells and improves the proliferation and cytotoxic activity of cytokine-induced killer cells. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 22495391	2012
Targeting cancer stem cells via dendritic-cell vaccination. Oncoimmunology\| PubMed ID: 23243607	2012
Effects of tumor irradiation on host T-regulatory cells and systemic immunity in the context of adoptive T-cell therapy in mice. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 23377667	2013
Cytokine-induced killer (CIK) cells bound with anti-CD3/anti-CD133 bispecific antibodies target CD133(high) cancer stem cells in vitro and in vivo. Clinical immunology (Orlando, Fla.)\| PubMed ID: 23994769	2013
IL-17A promotes immune cell recruitment in human esophageal cancers and the infiltrating dendritic cells represent a positive prognostic marker for patient survival. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 23994890	2013
Cancer immunotherapy: current status and future directions. Surgical oncology clinics of North America\| PubMed ID: 24012398	2013
OK-432 synergizes with IFN-γ to confer dendritic cells with enhanced antitumor immunity. Immunology and cell biology\| PubMed ID: 24296809	2013