David J. Bzik

Department of Microbiology and Immunology, The Geisel School of Medicine at Dartmouth

Affiliated withThe Geisel School of Medicine at Dartmouth

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 19	2013

Other Publications

Article	Year
De novo pyrimidine biosynthesis is required for virulence of Toxoplasma gondii. Nature\| PubMed ID: 11859373	2002
Plasmodium falciparum: fine-mapping of an epitope of the serine repeat antigen that is a target of parasite-inhibitory antibodies. Experimental parasitology\| PubMed ID: 12243740	2002
Differential localization of processed fragments of Plasmodium falciparum serine repeat antigen and further processing of its N-terminal 47 kDa fragment. Parasitology international\| PubMed ID: 12421632	2002
Organisation and sequence determination of glutamine-dependent carbamoyl phosphate synthetase II in Toxoplasma gondii. International journal for parasitology\| PubMed ID: 12547350	2003
Toxoplasma gondii lacks the enzymes required for de novo arginine biosynthesis and arginine starvation triggers cyst formation. International journal for parasitology\| PubMed ID: 15003493	2004
Inactivation of protozoan parasites in red blood cells using INACTINE PEN110 chemistry. Transfusion\| PubMed ID: 15104655	2004
Toxoplasma gondii: generation of novel truncation mutations in the linker domain of dihydrofolate reductase-thymidylate synthase. Experimental parasitology\| PubMed ID: 15172226	2004
Lack of IL-15 results in the suboptimal priming of CD4+ T cell response against an intracellular parasite. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16614074	2006
Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16751369	2006
NK cells enhance dendritic cell response against parasite antigens via NKG2D pathway. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17579080	2007
TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18714019	2008
Genetic identification of essential indels and domains in carbamoyl phosphate synthetase II of Toxoplasma gondii. International journal for parasitology\| PubMed ID: 18992249	2009
Cell-mediated immunity to Toxoplasma gondii develops primarily by local Th1 host immune responses in the absence of parasite replication. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19124750	2009
Efficient gene replacements in Toxoplasma gondii strains deficient for nonhomologous end joining. Eukaryotic cell\| PubMed ID: 19218423	2009
Kinetics and phenotype of vaccine-induced CD8+ T-cell responses to Toxoplasma gondii. Infection and immunity\| PubMed ID: 19528214	2009
Long-term immunity to lethal acute or chronic type II Toxoplasma gondii infection is effectively induced in genetically susceptible C57BL/6 mice by immunization with an attenuated type I vac... Infection and immunity\| PubMed ID: 19797073	2009
CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1. Infection and immunity\| PubMed ID: 20498261	2010
Avirulent uracil auxotrophs based on disruption of orotidine-5'-monophosphate decarboxylase elicit protective immunity to Toxoplasma gondii. Infection and immunity\| PubMed ID: 20605980	2010
Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence. Cell host & microbe\| PubMed ID: 21147463	2010
Type II Toxoplasma gondii KU80 knockout strains enable functional analysis of genes required for cyst development and latent infection. Eukaryotic cell\| PubMed ID: 21531875	2011
Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control. PLoS pathogens\| PubMed ID: 21931552	2011
An inside job: hacking into Janus kinase/signal transducer and activator of transcription signaling cascades by the intracellular protozoan Toxoplasma gondii. Infection and immunity\| PubMed ID: 22104110	2012
Biochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase from Toxoplasma gondii. Molecular and biochemical parasitology\| PubMed ID: 22580100	2012
Immune-mediated regression of established B16F10 melanoma by intratumoral injection of attenuated Toxoplasma gondii protects against rechallenge. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23225891	2013
Avirulent Toxoplasma gondii Generates Therapeutic Antitumor Immunity by Reversing Immunosuppression in the Ovarian Cancer Microenvironment. Cancer research\| PubMed ID: 23704211	2013