Shioko Kimura

Laboratory of Metabolism, National Institutes of Health

Affiliated withNational Institutes of Health

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 21	2013
Publication title Cited by 10	2015

Other Publications

Article	Year
Secretoglobin 3A2/uteroglobin-related protein 1 is a novel marker for pulmonary carcinoma in mice and humans. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 20466451	2011
A polymorphism in the human UGRP1 gene promoter that regulates transcription is associated with an increased risk of asthma. American journal of human genetics\| PubMed ID: 11813133	2002
Increased expression of thyroid transcription factor-1 (TTF-1) in respiratory epithelial cells inhibits alveolarization and causes pulmonary inflammation. Developmental biology\| PubMed ID: 11820807	2002
Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice. The Journal of clinical investigation\| PubMed ID: 11854318	2002
Pituitary hormones are not required for sexual differentiation of male mice: phenotype of the T/ebp/Nkx2.1 null mutant mice. Endocrinology\| PubMed ID: 12399445	2002
Study of P450 function using gene knockout and transgenic mice. Archives of biochemistry and biophysics\| PubMed ID: 12464254	2003
Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2. Carcinogenesis\| PubMed ID: 12663521	2003
Microarray analysis using amplified mRNA from laser capture microdissection of microscopic hepatocellular precancerous lesions and frozen hepatocellular carcinomas reveals unique and consist... Toxicologic pathology\| PubMed ID: 12746117	2003
Aberrant trajectory of ascending dopaminergic pathway in mice lacking Nkx2.1. Experimental neurology\| PubMed ID: 12821380	2003
Hypothyroidism in thyroid transcription factor 1 haploinsufficiency is caused by reduced expression of the thyroid-stimulating hormone receptor. Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 12907760	2003
[Homeodomain transcription factor T/EBP/NKX2.1 in development and differentiation of the thyroid and lung]. Seikagaku. The Journal of Japanese Biochemical Society\| PubMed ID: 14748143	2003
In vivo characterization of the Nkx2.1 promoter/enhancer elements in transgenic mice. Gene\| PubMed ID: 15094193	2004
Thyrocyte-specific expression of Cre recombinase in transgenic mice. Genesis (New York, N.Y. : 2000)\| PubMed ID: 15282748	2004
Developmental regulation of claudin localization by fetal alveolar epithelial cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15347569	2004
Interleukin-10 induces uteroglobin-related protein (UGRP) 1 gene expression in lung epithelial cells through homeodomain transcription factor T/EBP/NKX2.1. The Journal of biological chemistry\| PubMed ID: 15485815	2004
Decreased expression of uteroglobin-related protein 1 in inflamed mouse airways is mediated by IL-9. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15531759	2004
Progressive glomerulonephritis and histiocytic sarcoma associated with macrophage functional defects in CYP1B1-deficient mice. Toxicologic pathology\| PubMed ID: 15580705	2004
An integrated regulatory network controlling survival and migration in thyroid organogenesis. Developmental biology\| PubMed ID: 15581879	2004
Interleukin-5 reduces the expression of uteroglobin-related protein (UGRP) 1 gene in allergic airway inflammation. Immunology letters\| PubMed ID: 15626484	2005
Induction of uteroglobin-related protein 2 (Ugrp2) expression by EGF and TGFalpha. FEBS letters\| PubMed ID: 15811345	2005
Ventromedial hypothalamic nucleus-specific enhancer of Ad4BP/SF-1 gene. Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 15994202	2005
A mouse model demonstrates a multigenic origin of congenital hypothyroidism. Endocrinology\| PubMed ID: 16150900	2005
Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2. Chemical research in toxicology\| PubMed ID: 16167840	2005
Induction of uteroglobin-related protein 2 (Ugrp2) gene expression by the Th2 cytokines IL-4 and IL-13. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16237061	2005
Directed differentiation of neural cells to hypothalamic dopaminergic neurons. Development (Cambridge, England)\| PubMed ID: 16284116	2005
Origin of the ultimobranchial body cyst: T/ebp/Nkx2.1 expression is required for development and fusion of the ultimobranchial body to the thyroid. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 16342117	2006
Alterations in skin and stratified epithelia by constitutively activated PPARalpha. The Journal of investigative dermatology\| PubMed ID: 16374467	2006
Uteroglobin-related protein 1 expression suppresses allergic airway inflammation in mice. American journal of respiratory and critical care medicine\| PubMed ID: 16456148	2006
A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes. Molecular pharmacology\| PubMed ID: 16505155	2006
Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16510470	2006
Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid. Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 16601074	2006
Regulation of mouse hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-nicotinamide adenine dinucleotide pathway, by hepatocyte nucle... Molecular pharmacology\| PubMed ID: 16807375	2006
Peroxisome proliferator-activated receptor alpha activation during pregnancy severely impairs mammary lobuloalveolar development in mice. Endocrinology\| PubMed ID: 16857745	2006
Identification and expression of alternative splice variants of the mouse Ppp1r3b gene in lung epithelial cells. Biochemical and biophysical research communications\| PubMed ID: 16949035	2006
GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo. Development (Cambridge, England)\| PubMed ID: 17164424	2007
Deletion of the Ttf1 gene in differentiated neurons disrupts female reproduction without impairing basal ganglia function. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17182767	2006
A comprehensive investigation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism in the mouse using a multivariate data analysis approach. Chemical research in toxicology\| PubMed ID: 17279779	2007
Pten loss in the mouse thyroid causes goiter and follicular adenomas: insights into thyroid function and Cowden disease pathogenesis. Cancer research\| PubMed ID: 17283127	2007
Side population cells in the mouse thyroid exhibit stem/progenitor cell-like characteristics. Endocrinology\| PubMed ID: 17584961	2007
Plasma UGRP1 levels associate with promoter G-112A polymorphism and the severity of asthma. Allergology international : official journal of the Japanese Society of Allergology\| PubMed ID: 18089940	2008
Regulation of mouse Scgb3a1 gene expression by NF-Y and association of CpG methylation with its tissue-specific expression. BMC molecular biology\| PubMed ID: 18194566	2008
Role of secretoglobin 3A2 in lung development. American journal of respiratory and critical care medicine\| PubMed ID: 18535256	2008
CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression. The Journal of biological chemistry\| PubMed ID: 18632661	2008
The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes. Neuron\| PubMed ID: 18786356	2008
Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors. Neuron\| PubMed ID: 18786357	2008
Oncostatin M regulates secretoglobin 3A1 and 3A2 expression in a bidirectional manner. American journal of respiratory cell and molecular biology\| PubMed ID: 18978304	2009
IFN-gamma down-regulates Secretoglobin 3A1 gene expression. Biochemical and biophysical research communications\| PubMed ID: 19135978	2009
Expression of secretoglobin3A2 (SCGB3A2) in primary pulmonary carcinomas. Fukushima journal of medical science\| PubMed ID: 19418968	2008
Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine-induced thyroid adenoma in mice. Carcinogenesis\| PubMed ID: 19581346	2009
The proximal STAT6 and NF-kappaB sites are responsible for IL-13- and TNF-alpha-induced RhoA transcriptions in human bronchial smooth muscle cells. Pharmacological research\| PubMed ID: 20006706	2010
The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20181579	2010
Identification and characterization of rat RhoA gene promoter. Journal of pharmacological sciences\| PubMed ID: 20308800	2010
Development of thyroid gland and ultimobranchial body cyst is independent of p63. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 20697379	2011
A functional interaction between CPI-17 and RACK1 proteins in bronchial smooth muscle cells. Biochemical and biophysical research communications\| PubMed ID: 20875397	2010
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21220306	2011
FOXA1 plays a role in regulating secretoglobin 1a1 expression in the absence of CCAAT/enhancer binding protein activities in lung in vivo. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 21224212	2011
Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by transforming growth factor beta signaling down-regulation. The Journal of biological chemistry\| PubMed ID: 21478551	2011
Experience dictates stem cell fate in the adult hippocampus. Neuron\| PubMed ID: 21658584	2011
Thyroid-specific transcription factors and their roles in thyroid cancer. Journal of thyroid research\| PubMed ID: 21687604	2011
Wnt/β-catenin signaling pathway is a direct enhancer of thyroid transcription factor-1 in human papillary thyroid carcinoma cells. PloS one\| PubMed ID: 21814573	2011
Conditional deletion of insulin receptor in thyrocytes does not affect thyroid structure and function. Endocrine journal\| PubMed ID: 21908931	2011
The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1. The European journal of neuroscience\| PubMed ID: 22098391	2011
Thyroid-specific knockout of the tumor suppressor mitogen-inducible gene 6 activates epidermal growth factor receptor signaling pathways and suppresses nuclear factor-κB activity. Surgery\| PubMed ID: 22136853	2011
Thyroid regeneration: characterization of clear cells after partial thyroidectomy. Endocrinology\| PubMed ID: 22454152	2012
Soluble vascular adhesion protein-1 accumulates in proliferative diabetic retinopathy. Investigative ophthalmology & visual science\| PubMed ID: 22618595	2012
Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22797898	2012
Deficiency of CCAAT/enhancer binding protein family DNA binding prevents malignant conversion of adenoma to carcinoma in NNK-induced lung carcinogenesis in the mouse. Molecular cancer\| PubMed ID: 23234329	2012
Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma. Molecular cell\| PubMed ID: 23523371	2013
Noninvasive monitoring of pulmonary fibrosis by targeting matrix metalloproteinases (MMPs). Molecular pharmaceutics\| PubMed ID: 23607644	2013
Postnatal expression of BRAFV600E does not induce thyroid cancer in mouse models of thyroid papillary carcinoma. Endocrinology\| PubMed ID: 23970782	2013
Preclinical evaluation of human secretoglobin 3A2 in mouse models of lung development and fibrosis. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 24213919	2014
Stem cell antigen 1-positive mesenchymal cells are the origin of follicular cells during thyroid regeneration. PloS one\| PubMed ID: 24278321	2013
Molecular cloning and functional characterization of two forms of Pax8 in the rainbow trout, Oncorhynchus mykiss. General and comparative endocrinology\| PubMed ID: 24380675	2014
Regulation of LH/FSH expression by secretoglobin 3A2 in the mouse pituitary gland. Cell and tissue research\| PubMed ID: 24514953	2014
Thyroid regeneration: how stem cells play a role? Frontiers in endocrinology\| PubMed ID: 24782833	2014
Secretoglobin superfamily protein SCGB3A2 deficiency potentiates ovalbumin-induced allergic pulmonary inflammation. Mediators of inflammation\| PubMed ID: 25242865	2014
Activation of intestinal human pregnane X receptor protects against azoxymethane/dextran sulfate sodium-induced colon cancer. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 25277138	2014
Expression of stanniocalcin 1 in thyroid side population cells and thyroid cancer cells. Thyroid : official journal of the American Thyroid Association\| PubMed ID: 25647164	2015
SCGB3A2 Inhibits Acrolein-Induced Apoptosis through Decreased p53 Phosphorylation. Acta histochemica et cytochemica\| PubMed ID: 26019375	2015
Fat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans. Gastroenterology\| PubMed ID: 26099526	2015
KRAS(G12D)-mediated oncogenic transformation of thyroid follicular cells requires long-term TSH stimulation and is regulated by SPRY1. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 26146959	2015
Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice. BMC pulmonary medicine\| PubMed ID: 26178733	2015