John R. Grider

Physiology and Biophyics, Virginia Commonwealth University

Affiliated withVirginia Commonwealth University

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 68	2013
Publication title Cited by 26	2016

Other Publications

Article	Year
GDNF availability determines enteric neuron number by controlling precursor proliferation. Development (Cambridge, England)\| PubMed ID: 12668632	2003
Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via Gi3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediate... The Biochemical journal\| PubMed ID: 12733988	2003
Inhibition of sustained smooth muscle contraction by PKA and PKG preferentially mediated by phosphorylation of RhoA. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 12736149	2003
Physiological role of neuropeptide Y in the regulation of the ascending phase of the peristaltic reflex. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 12919938	2003
Neurotransmitters mediating the intestinal peristaltic reflex in the mouse. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 12966154	2003
Gastrin-releasing peptide is a modulatory neurotransmitter of the descending phase of the peristaltic reflex. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 15297260	2004
Coexpression of Y1, Y2, and Y4 receptors in smooth muscle coupled to distinct signaling pathways. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 15308651	2004
Gq/G13 signaling by ET-1 in smooth muscle: MYPT1 phosphorylation via ETA and CPI-17 dephosphorylation via ETB. American journal of physiology. Cell physiology\| PubMed ID: 15475516	2004
Differential expression of Y receptors and signaling pathways in intestinal circular and longitudinal smooth muscle. Regulatory peptides\| PubMed ID: 15582728	2005
Desensitization of the peristaltic reflex induced by mucosal stimulation with the selective 5-HT4 agonist tegaserod. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 16223945	2006
Brain-derived neurotrophic factor augments peristalsis by augmenting 5-HT and calcitonin gene-related peptide release. Gastroenterology\| PubMed ID: 16530518	2006
Cross-regulation of VPAC(2) receptor desensitization by M(3) receptors via PKC-mediated phosphorylation of RKIP and inhibition of GRK2. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 17170028	2007
Up-regulation of calcitonin gene-related peptide and receptor tyrosine kinase TrkB in rat bladder afferent neurons following TNBS colitis. Experimental neurology\| PubMed ID: 17303123	2007
Autoinhibition of endothelial nitric oxide synthase (eNOS) in gut smooth muscle by nitric oxide. Regulatory peptides\| PubMed ID: 18926858	2008
Alterations to enteric neural signaling underlie secretory abnormalities of the ileum in experimental colitis in the guinea pig. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 19221017	2009
Endogenous IGF-I and alpha v beta3 integrin ligands regulate increased smooth muscle growth in TNBS-induced colitis. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 19359426	2009
Colitis induces calcitonin gene-related peptide expression and Akt activation in rat primary afferent pathways. Experimental neurology\| PubMed ID: 19422825	2009
Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 19589944	2009
Endogenous IGF-I and alphaVbeta3 integrin ligands regulate increased smooth muscle hyperplasia in stricturing Crohn's disease. Gastroenterology\| PubMed ID: 19751734	2010
The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20107080	2010
Colitis elicits differential changes in the expression levels of receptor tyrosine kinase TrkA and TrkB in colonic afferent neurons: a possible involvement of axonal transport. Pain\| PubMed ID: 20638179	2010
Amelioration of excess collagen IÎ±I, fibrosis, and smooth muscle growth in TNBS-induced colitis in IGF-I(+/-) mice. Inflammatory bowel diseases\| PubMed ID: 20722057	2011
Endogenous IGFBP-3 regulates excess collagen expression in intestinal smooth muscle cells of Crohn's disease strictures. Inflammatory bowel diseases\| PubMed ID: 20848532	2011
Inhibition of monoacylglycerol lipase attenuates nonsteroidal anti-inflammatory drug-induced gastric hemorrhages in mice. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 21659471	2011
Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat. Journal of neuroinflammation\| PubMed ID: 22335898	2012
Up-regulation of brain-derived neurotrophic factor is regulated by extracellular signal-regulated protein kinase 5 and by nerve growth factor retrograde signaling in colonic afferent neurons... Experimental neurology\| PubMed ID: 22921460	2012
Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic Î² cells. Biochemical and biophysical research communications\| PubMed ID: 23022524	2012
Morphine decreases enteric neuron excitability via inhibition of sodium channels. PloS one\| PubMed ID: 23028881	2012
The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice. Gastroenterology\| PubMed ID: 23041323	2013
Activation of G protein-coupled bile acid receptor, TGR5, induces smooth muscle relaxation via both Epac- and PKA-mediated inhibition of RhoA/Rho kinase pathway. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 23275618	2013
Electrophysiological characteristics of enteric neurons isolated from the immortomouse. Digestive diseases and sciences\| PubMed ID: 23371009	2013
Caveolae-dependent internalization and homologous desensitization of VIP/PACAP receptor, VPACâ‚‚, in gastrointestinal smooth muscle. Peptides\| PubMed ID: 23499767	2013
Characterization of signaling pathways coupled to melatonin receptors in gastrointestinal smooth muscle. Regulatory peptides\| PubMed ID: 23541890	2013
TRPM5-dependent amiloride- and benzamil-insensitive NaCl chorda tympani taste nerve response. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 23639808	2013
Differential Expression of Multidrug-Resistance Protein 5 and Phosphodiesterase 5 and Regulation of cGMP Levels in Phasic and Tonic Smooth Muscle. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 23764893	2013
Differential regulation of muscarinic M2 and M3 receptor signaling in gastrointestinal smooth muscle by caveolin-1. American journal of physiology. Cell physiology\| PubMed ID: 23784544	2013
Changes in the Expression of Smooth Muscle Contractile Proteins in TNBS- and DSS-Induced Colitis in Mice. Inflammation\| PubMed ID: 23794034	2013
Retinaldehyde dehydrogenase enzymes regulate colon enteric nervous system structure and function. Developmental biology\| PubMed ID: 23806210	2013
Distinctive G Protein-Dependent Signaling by Protease-Activated Receptor 2 (PAR2) in Smooth Muscle: Feedback Inhibition of RhoA by cAMP-Independent PKA. PloS one\| PubMed ID: 23825105	2013