Samuel H. Wilson

Samuel H. Wilson

Laboratory of Structural Biology, NIEHS, National Institutes of Health

Affiliated withNIEHS, National Institutes of HealthNational Institute of Environmental Health Sciences, National Institutes of Health

Research Area

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JoVE Journal Publications

ArticleTotal : 2
Year
Steady-state, Pre-steady-state, and Single-turnover Kinetic Measurement for DNA Glycosylase Activity
Publication title

Cited by 26

2013
2022

Other Publications

Article
Year
The domain organization and properties of individual domains of DNA topoisomerase V, a type 1B topoisomerase with DNA repair activities.

The Journal of biological chemistry| PubMed ID: 11733530

2002
2002
DNA polymerase beta.

The international journal of biochemistry & cell biology| PubMed ID: 11854030

2002
2002
2002
Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 11983862

2002
2002
2002
Efficiency of correct nucleotide insertion governs DNA polymerase fidelity.

The Journal of biological chemistry| PubMed ID: 12370169

2002
Rapid segmental and subdomain motions of DNA polymerase beta.

The Journal of biological chemistry| PubMed ID: 12458221

2003
Mapping of the interaction interface of DNA polymerase beta with XRCC1.

Structure (London, England : 1993)| PubMed ID: 12467578

2002
2002
2003
2003
2003
2003
2003
2003
2003
Structural insights into the origins of DNA polymerase fidelity.

Structure (London, England : 1993)| PubMed ID: 12737815

2003
2003
Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 12799467

2003
2003
2003
2003
2004
Recombinogenic phenotype of human activation-induced cytosine deaminase.

Journal of immunology (Baltimore, Md. : 1950)| PubMed ID: 15034045

2004
Shaping science policy in the age of genomics.

Nature reviews. Genetics| PubMed ID: 15134075

2004
2004
2004
2004
Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase.

The Journal of clinical investigation| PubMed ID: 15199406

2004
The Environmental Genome Project: phase I and beyond.

Molecular interventions| PubMed ID: 15210868

2004
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly.

Journal of the American Chemical Society| PubMed ID: 15238001

2004
2004
2004
2004
In situ analysis of repair processes for oxidative DNA damage in mammalian cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 15365186

2004
2004
2005
2005
2005
2005
2005
2005
2005
2005
2005
Strategic planning: establishing need and clarifying motivation.

Environmental health perspectives| PubMed ID: 16079048

2005
2005
2005
2005
The need for exposure health sciences.

Environmental health perspectives| PubMed ID: 16203220

2005
2005
Syn-full behavior by T7 DNA polymerase.

Structure (London, England : 1993)| PubMed ID: 16271879

2005
2005
2006
Structure and mechanism of DNA polymerase Beta.

Chemical reviews| PubMed ID: 16464010

2006
Magnesium-induced assembly of a complete DNA polymerase catalytic complex.

Structure (London, England : 1993)| PubMed ID: 16615916

2006
2006
Activities and mechanism of DNA polymerase beta.

Methods in enzymology| PubMed ID: 16793365

2006
Disease-first: a new paradigm for environmental health science research.

Environmental health perspectives| PubMed ID: 16835037

2006
2006
Energy analysis of chemistry for correct insertion by DNA polymerase beta.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16938895

2006
2006
2006
Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 17079493

2006
2007
2007
2007
2006
2007
2007
2007
2007
2007
2007
2007
2007
2007
2008
2007
2007
2007
(R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta.

Journal of the American Chemical Society| PubMed ID: 18031037

2007
2008
2008
Incorrect nucleotide insertion at the active site of a G:A mismatch catalyzed by DNA polymerase beta.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 18391201

2008
DNA damage response protein ASCIZ links base excision repair with immunoglobulin gene conversion.

Biochemical and biophysical research communications| PubMed ID: 18433721

2008
2008
2008
Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 18614692

2008
2008
2008
2008
2009
2009
2009
2009
Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion.

The Journal of biological chemistry| PubMed ID: 19674974

2009
2009
2009
2009
DNA polymerase beta substrate specificity: side chain modulation of the "A-rule".

The Journal of biological chemistry| PubMed ID: 19759017

2009
2010
HMGB1: roles in base excision repair and related function.

Biochimica et biophysica acta| PubMed ID: 20123074

2010
2010
2010
2010
2010
2010
2010
Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20724659

2010
2010
2010
Base excision repair and design of small molecule inhibitors of human DNA polymerase β.

Cellular and molecular life sciences : CMLS| PubMed ID: 20844920

2010
Substrate channeling in mammalian base excision repair pathways: passing the baton.

The Journal of biological chemistry| PubMed ID: 20952393

2010
2011
Molecular insights into DNA polymerase deterrents for ribonucleotide insertion.

The Journal of biological chemistry| PubMed ID: 21733843

2011
2012
2011
2012
Binary complex crystal structure of DNA polymerase β reveals multiple conformations of the templating 8-oxoguanine lesion.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 22178760

2012
2012
DNA base excision repair: a mechanism of trinucleotide repeat expansion.

Trends in biochemical sciences| PubMed ID: 22285516

2012
Stereospecific formation of a ternary complex of (S)-α,β-fluoromethylene-dATP with DNA pol β.

Chembiochem : a European journal of chemical biology| PubMed ID: 22315190

2012
2012
2012
Structures of dNTP intermediate states during DNA polymerase active site assembly.

Structure (London, England : 1993)| PubMed ID: 22959623

2012
2012
2012
2012
DNA polymerase β gap-filling translesion DNA synthesis.

Chemical research in toxicology| PubMed ID: 23121263

2012
2013
2012
2012
Predicting enhanced cell killing through PARP inhibition.

Molecular cancer research : MCR| PubMed ID: 23193155

2013
2013
2012
2013
2013
2013
2013
2013
2013
Structure and mechanism of DNA polymerase β.

Biochemistry| PubMed ID: 24717170

2014
2014
The dark side of DNA repair.

eLife| PubMed ID: 24844708

2014
2014
2015
Structures of human DNA polymerases ν and θ expose their end game.

Nature structural & molecular biology| PubMed ID: 25837870

2015
2015
2015
Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 26243878

2015
Requirement for transient metal ions revealed through computational analysis for DNA polymerase going in reverse.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 26351676

2015
Capturing snapshots of APE1 processing DNA damage.

Nature structural & molecular biology| PubMed ID: 26458045

2015
2016
2016
2016
2015
2016
2016
2017
2017
2017
2017
2017
2017
2017
2017
2017
2017
2018
Transcriptional mutagenesis mediated by 8-oxoG induces translational errors in mammalian cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 29610342

2018
2018
2018
2018
2018
2018
2019
2019
2019
Eukaryotic Base Excision Repair: New Approaches Shine Light on Mechanism.

Annual review of biochemistry| PubMed ID: 31220977

2019
2019
2019
2020
2020
2020
2020
2020
2020
2020
2020
2020
2020
2020
2021
2021
2021
2022