Lynne S. Cox

Department of Biochemistry, University of Oxford

Affiliated withUniversity of Oxford

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2013

Other Publications

Article	Year
Identification of a second proliferating cell nuclear antigen in the human malarial pathogen Plasmodium falciparum. International journal for parasitology\| PubMed ID: 12464414	2002
Characterisation of a sexual stage-specific gene encoding ORC1 homologue in the human malaria parasite Plasmodium falciparum. Parasitology international\| PubMed ID: 12543146	2003
Characterisation of the interaction between WRN, the helicase/exonuclease defective in progeroid Werner's syndrome, and an essential replication factor, PCNA. Mechanisms of ageing and development\| PubMed ID: 12633936	2003
Asymmetry of DNA replication fork progression in Werner's syndrome. Aging cell\| PubMed ID: 12882351	2002
Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I. Experimental cell research\| PubMed ID: 14729473	2004
Correction of proliferation and drug sensitivity defects in the progeroid Werner's Syndrome by Holliday junction resolution. Rejuvenation research\| PubMed ID: 17378750	2007
Modeling Werner Syndrome in Drosophila melanogaster: hyper-recombination in flies lacking WRN-like exonuclease. Annals of the New York Academy of Sciences\| PubMed ID: 18056975	2007
Identification and characterization of a Drosophila ortholog of WRN exonuclease that is required to maintain genome integrity. Aging cell\| PubMed ID: 18346216	2008
DmWRNexo is a 3'-5' exonuclease: phenotypic and biochemical characterization of mutants of the Drosophila orthologue of human WRN exonuclease. Biogerontology\| PubMed ID: 18956248	2009
Cell senescence: the future of ageing? Biogerontology\| PubMed ID: 19115080	2009
Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes? Aging cell\| PubMed ID: 19678809	2009
Live fast, die young: new lessons in mammalian longevity. Rejuvenation research\| PubMed ID: 19725776	2009
Prospects for rejuvenation of aged tissue by telomerase reactivation. Rejuvenation research\| PubMed ID: 21226558	2010
Recapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRN helicase/exonuclease. Biogerontology\| PubMed ID: 21786128	2012
The role of DNA exonucleases in protecting genome stability and their impact on ageing. Age (Dordrecht, Netherlands)\| PubMed ID: 21948156	2012
The Drosophila orthologue of progeroid human WRN exonuclease, DmWRNexo, cleaves replication substrates but is inhibited by uracil or abasic sites : analysis of DmWRNexo activity in vitro. Age (Dordrecht, Netherlands)\| PubMed ID: 22562358	2013