Annarosa Arcangeli Department of Experimental and Clinical Medicine, Section of Internal Medicine University of Florence Biography Publications Institution JoVE Articles Annarosa Arcangeli has not added a biography. If you are Annarosa Arcangeli and would like to personalize this page please email our Author Liaison for assistance. Publications Circulating MiRNome Profiling Data in Behçet's Syndrome Data in Brief. Oct, 2021 | Pubmed ID: 34632024 A Transcriptomic Approach Reveals Selective Ribosomal Remodelling in the Tumour Versus the Stromal Compartment of Metastatic Colorectal Cancer Cancers. Aug, 2021 | Pubmed ID: 34439343 Neonatal Nav1.5 Protein Expression in Human Colorectal Cancer: Immunohistochemical Characterization and Clinical Evaluation Cancers. Jul, 2021 | Pubmed ID: 34359733 Harnessing the HERG1/β1 Integrin Complex Via a Novel Bispecific Single-chain Antibody: An Effective Strategy Against Solid Cancers Molecular Cancer Therapeutics. 08, 2021 | Pubmed ID: 34045227 Extracellular Signal-Regulated Kinase 5 Regulates the Malignant Phenotype of Cholangiocarcinoma Cells Hepatology (Baltimore, Md.). Oct, 2021 | Pubmed ID: 33959996 Transgenic Mice Overexpressing the LH Receptor in the Female Reproductive System Spontaneously Develop Endometrial Tumour Masses Scientific Reports. 04, 2021 | Pubmed ID: 33893331 Expression and Purification of a Novel Single-chain Diabody (scDb-hERG1/β1) from Pichia Pastoris Transformants Protein Expression and Purification. 08, 2021 | Pubmed ID: 33826963 Mitochondrial Oxidative Metabolism Contributes to a Cancer Stem Cell Phenotype in Cholangiocarcinoma Journal of Hepatology. 06, 2021 | Pubmed ID: 33484774 Data Describing the Effects of Potassium Channels Modulators on Outward Currents Measured in Human Lymphoma Cell Lines Data in Brief. Feb, 2021 | Pubmed ID: 33385031 and Mutation Detection in Circulating DNA from Patients with Metastatic Colorectal Cancer Using BEAMing Assay: Concordance with Standard Biopsy and Clinical Evaluation Oncology Letters. Jan, 2021 | Pubmed ID: 33240421 Ion Channels Orchestrate Pancreatic Ductal Adenocarcinoma Progression and Therapy Frontiers in Pharmacology. 2020 | Pubmed ID: 33841132 Analysis of Resorbable Mesh Implants in Short-term Human Muscular Fascia Cultures: a Pilot Study Hernia : the Journal of Hernias and Abdominal Wall Surgery. 12, 2020 | Pubmed ID: 32725294 K11.1 Potassium Channel and the Na/H Antiporter NHE1 Modulate Adhesion-Dependent Intracellular PH in Colorectal Cancer Cells Frontiers in Pharmacology. 2020 | Pubmed ID: 32587517 Correction: Clarithromycin Inhibits Autophagy in Colorectal Cancer by Regulating the HERG1 Potassium Channel Interaction with PI3K Cell Death & Disease. Mar, 2020 | Pubmed ID: 32231201 Proton Pump Inhibitors Reduce Pancreatic Adenocarcinoma Progression by Selectively Targeting H, K-ATPases in Pancreatic Cancer and Stellate Cells Cancers. Mar, 2020 | Pubmed ID: 32164284 Clarithromycin Inhibits Autophagy in Colorectal Cancer by Regulating the HERG1 Potassium Channel Interaction with PI3K Cell Death & Disease. 03, 2020 | Pubmed ID: 32123164 HERG1 and HIF-2α Behave As Biomarkers of Positive Response to Bevacizumab in Metastatic Colorectal Cancer Patients Translational Oncology. Mar, 2020 | Pubmed ID: 32105990 HERG1 and CA IX Expression Are Associated with Disease Recurrence in Surgically Resected Clear Cell Renal Carcinoma European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 01, 2020 | Pubmed ID: 31679954 Bioelectricity of Cancer Bioelectricity. Sep, 2019 | Pubmed ID: 34471814 The HERG1 Potassium Channel Behaves As Prognostic Factor In Gastric Dysplasia Endoscopic Samples OncoTargets and Therapy. 2019 | Pubmed ID: 31807018 Ion Channel Targeting with Antibodies and Antibody Fragments for Cancer Diagnosis Antibodies (Basel, Switzerland). May, 2019 | Pubmed ID: 31544839 Data Describing the Effects of the Macrolide Antibiotic Clarithromycin on Preclinical Mouse Models of Colorectal Cancer Data in Brief. Oct, 2019 | Pubmed ID: 31508470 The Ion Channels and Transporters Gene Expression Profile Indicates a Shift in Excitability and Metabolisms During Malignant Progression of Follicular Lymphoma Scientific Reports. 06, 2019 | Pubmed ID: 31197180 Replacement of the Thiosugar of Auranofin with Iodide Enhances the Anticancer Potency in a Mouse Model of Ovarian Cancer ACS Medicinal Chemistry Letters. Apr, 2019 | Pubmed ID: 30996813 The Activity of Kv 11.1 Potassium Channel Modulates F-Actin Organization During Cell Migration of Pancreatic Ductal Adenocarcinoma Cells Cancers. Jan, 2019 | Pubmed ID: 30678127 Ion Channel Conformations Regulate Integrin-Dependent Signaling Trends in Cell Biology. 04, 2019 | Pubmed ID: 30635161 Peptides and Small Molecules Blocking the CXCR4/CXCL12 Axis Overcome Bone Marrow‑induced Chemoresistance in Acute Leukemias Oncology Reports. Jan, 2019 | Pubmed ID: 30365110 Generation and Characterization of Novel Recombinant Anti-hERG1 ScFv Antibodies for Cancer Molecular Imaging Oncotarget. Oct, 2018 | Pubmed ID: 30405887 HERG1 Channel Expression Associates with Molecular Subtypes and Prognosis in Breast Cancer Cancer Cell International. 2018 | Pubmed ID: 30002601 Postnatal Changes in K/Cl Cotransporter-2 Expression in the Forebrain of Mice Bearing a Mutant Nicotinic Subunit Linked to Sleep-Related Epilepsy Neuroscience. 08, 2018 | Pubmed ID: 29949744 Engineering L-asparaginase for Spontaneous Formation of Calcium Phosphate Bioinspired Microreactors Physical Chemistry Chemical Physics : PCCP. May, 2018 | Pubmed ID: 29697113 The Combined Activation of K3.1 and Inhibition of K11.1/hERG1 Currents Contribute to Overcome Cisplatin Resistance in Colorectal Cancer Cells British Journal of Cancer. 01, 2018 | Pubmed ID: 29161243 Circulating Endothelial Progenitor Cells in Type 1 Diabetic Patients: Relation with Patients' Age and Disease Duration Frontiers in Endocrinology. 2017 | Pubmed ID: 29109697 Auranofin, EtPAuCl, and EtPAuI Are Highly Cytotoxic on Colorectal Cancer Cells: A Chemical and Biological Study ACS Medicinal Chemistry Letters. Oct, 2017 | Pubmed ID: 29057040 A Novel Microfluidic 3D Platform for Culturing Pancreatic Ductal Adenocarcinoma Cells: Comparison with in Vitro Cultures and in Vivo Xenografts Scientific Reports. 04, 2017 | Pubmed ID: 28465513 The Conformational State of HERG1 Channels Determines Integrin Association, Downstream Signaling, and Cancer Progression Science Signaling. Apr, 2017 | Pubmed ID: 28377405 HERG Channels: From Antitargets to Novel Targets for Cancer Therapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2017 | Pubmed ID: 27903676 HERG1 Positivity and Glut-1 Negativity Identifies High-risk TNM Stage I and II Colorectal Cancer Patients, Regardless of Adjuvant Chemotherapy OncoTargets and Therapy. 2016 | Pubmed ID: 27789963 LH/hCG-Receptor Expression May Have a Negative Prognostic Value in Low-Risk Endometrial Cancer Frontiers in Oncology. 2016 | Pubmed ID: 27610354 HERG1 Behaves As Biomarker of Progression to Adenocarcinoma in Barrett's Esophagus and Can Be Exploited for a Novel Endoscopic Surveillance Oncotarget. Sep, 2016 | Pubmed ID: 27517748 Cisplatin and Its Dibromido Analogue: a Comparison of Chemical and Biological Profiles Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine. 06, 2016 | Pubmed ID: 27086032 Tumor-selective Peptide-carrier Delivery of Paclitaxel Increases in Vivo Activity of the Drug Scientific Reports. Dec, 2015 | Pubmed ID: 26626158 HERG1 Potassium Channels: Novel Biomarkers in Human Solid Cancers BioMed Research International. 2015 | Pubmed ID: 26339650 Cis-Pt I2(NH3)2: a Reappraisal Dalton Transactions (Cambridge, England : 2003). Sep, 2015 | Pubmed ID: 26226326 Novel Perspectives in Cancer Therapy: Targeting Ion Channels Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. Jul-Aug, 2015 | Pubmed ID: 26183291 Design, Synthesis and Characterisation of New Chimeric Ruthenium(II)-gold(I) Complexes As Improved Cytotoxic Agents Dalton Transactions (Cambridge, England : 2003). Jun, 2015 | Pubmed ID: 25996553 Lymphatic Endothelial Progenitor Cells and Vascular Endothelial Growth Factor-C in Spondyloarthritis and Crohn's Disease: Two Overlapping Diseases? Clinical and Experimental Rheumatology. Mar-Apr, 2015 | Pubmed ID: 25664492 Ion Channel Expression As Promising Cancer Biomarker Biochimica Et Biophysica Acta. Oct, 2015 | Pubmed ID: 25542783 New Pyrimido-indole Compound CD-160130 Preferentially Inhibits the KV11.1B Isoform and Produces Antileukemic Effects Without Cardiotoxicity Molecular Pharmacology. Feb, 2015 | Pubmed ID: 25411366 NAMI-A is Highly Cytotoxic Toward Leukaemia Cell Lines: Evidence of Inhibition of KCa 3.1 Channels Dalton Transactions (Cambridge, England : 2003). Aug, 2014 | Pubmed ID: 24975719 VEGF-A Clinical Significance in Gastric Cancers: Immunohistochemical Analysis of a Wide Italian Cohort European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. Oct, 2014 | Pubmed ID: 24784776 Time Resolved SAXS to Study the Complexation of SiRNA with Cationic Micelles of Divalent Surfactants Soft Matter. Apr, 2014 | Pubmed ID: 24651873 Interaction of Tumour Cells with Their Microenvironment: Ion Channels and Cell Adhesion Molecules. A Focus on Pancreatic Cancer Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Mar, 2014 | Pubmed ID: 24493749 HERG1 Channels Regulate VEGF-A Secretion in Human Gastric Cancer: Clinicopathological Correlations and Therapeutical Implications Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2014 | Pubmed ID: 24449824 Searching for Protein Binding Sites from Molecular Dynamics Simulations and Paramagnetic Fragment-based NMR Studies Biochimica Et Biophysica Acta. Mar, 2014 | Pubmed ID: 24373878 Advances in Lipid-based Platforms for RNAi Therapeutics Journal of Medicinal Chemistry. Feb, 2014 | Pubmed ID: 24047101 Characterization of HERG1 Channel Role in Mouse Colorectal Carcinogenesis Cancer Medicine. Oct, 2013 | Pubmed ID: 24403225 Development of Novel Anti-Kv 11.1 Antibody-conjugated PEG-TiO Nanoparticles for Targeting Pancreatic Ductal Adenocarcinoma Cells Journal of Nanoparticle Research : an Interdisciplinary Forum for Nanoscale Science and Technology. 2013 | Pubmed ID: 24348091 Over-Expression of the LH Receptor Increases Distant Metastases in an Endometrial Cancer Mouse Model Frontiers in Oncology. 2013 | Pubmed ID: 24312898 HERG1 Channels Modulate Integrin Signaling to Trigger Angiogenesis and Tumor Progression in Colorectal Cancer Scientific Reports. Nov, 2013 | Pubmed ID: 24270902 An Analytical Method for the Quantification of HERG1 Channel Gene Expression in Human Colorectal Cancer Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. Dec, 2013 | Pubmed ID: 24193004 High HERG1 Expression in Advanced Melanoma Melanoma Research. Jun, 2013 | Pubmed ID: 23524483 Immunohistochemical Biomarkers in Gastric Cancer Research and Management International Journal of Surgical Oncology. 2012 | Pubmed ID: 22778942 HERG1 Channels and Glut-1 As Independent Prognostic Indicators of Worse Outcome in Stage I and II Colorectal Cancer: A Pilot Study Translational Oncology. Apr, 2012 | Pubmed ID: 22496927 Deterministic and Stochastic Aspects of VEGF-A Production and the Cooperative Behavior of Tumoral Cell Colony Journal of Theoretical Biology. Mar, 2011 | Pubmed ID: 21167179 New Trends in Cancer Therapy: Targeting Ion Channels and Transporters Pharmaceuticals (Basel, Switzerland). Apr, 2010 | Pubmed ID: 27713296 Irresponsiveness of Two Retinoblastoma Cases to Conservative Therapy Correlates with Up- Regulation of HERG1 Channels and of the VEGF-A Pathway BMC Cancer. 2010 | Pubmed ID: 20860824 Physical and Functional Interaction Between Integrins and HERG1 Channels in Cancer Cells Advances in Experimental Medicine and Biology. 2010 | Pubmed ID: 20549940 Optical Methods in the Study of Protein-protein Interactions Advances in Experimental Medicine and Biology. 2010 | Pubmed ID: 20549938 Integrin Structure and Functional Relation with Ion Channels Advances in Experimental Medicine and Biology. 2010 | Pubmed ID: 20549935 HLH/hCG-receptor Expression Correlates with in Vitro Invasiveness in Human Primary Endometrial Cancer Gynecologic Oncology. Dec, 2008 | Pubmed ID: 18829089 Identification of a Posttranslational Mechanism for the Regulation of HERG1 K+ Channel Expression and HERG1 Current Density in Tumor Cells Molecular and Cellular Biology. Aug, 2008 | Pubmed ID: 18559421 HERG1 Channels in Human Esophagus: Evidence for Their Aberrant Expression in the Malignant Progression of Barrett's Esophagus Journal of Cellular Physiology. Nov, 2006 | Pubmed ID: 16883575 A HERG Current Sustains a Cardiac-type Action Potential in Neuroblastoma S Cells Biochemical and Biophysical Research Communications. Feb, 2003 | Pubmed ID: 12593854 Generation of an Orthotopic Xenograft of Pancreatic Cancer Cells by Ultrasound-Guided Injection Tiziano Lottini1, Matteo Buonamici1, Claudia Duranti1, Annarosa Arcangeli1 1Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence JoVE 63123 Cancer Research
Generation of an Orthotopic Xenograft of Pancreatic Cancer Cells by Ultrasound-Guided Injection Tiziano Lottini1, Matteo Buonamici1, Claudia Duranti1, Annarosa Arcangeli1 1Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence JoVE 63123 Cancer Research