James S. Schwaber Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Anatomy, and Cell Biology Thomas Jefferson University Biography Publications Institution JoVE Articles James S. Schwaber has not added a biography. If you are James S. Schwaber and would like to personalize this page please email our Author Liaison for assistance. Publications Single Cell Scale Neuronal and Glial Gene Expression and Putative Cell Phenotypes and Networks in the Nucleus Tractus Solitarius in an Alcohol Withdrawal Time Series Frontiers in Systems Neuroscience. 2021 | Pubmed ID: 34867221 3D Single Cell Scale Anatomical Map of Sex-dependent Variability of the Rat Intrinsic Cardiac Nervous System IScience. Jul, 2021 | Pubmed ID: 34355144 A Single Cell Transcriptomics Map of Paracrine Networks in the Intrinsic Cardiac Nervous System IScience. Jul, 2021 | Pubmed ID: 34337356 Mapping the Little Brain at the Heart by an Interdisciplinary Systems Biology Team IScience. May, 2021 | Pubmed ID: 34113808 Systemic Immune Bias Delineates Malignant Astrocytoma Survival Cohorts Journal of Immunology (Baltimore, Md. : 1950). 04, 2021 | Pubmed ID: 33685995 Input-output Signal Processing Plasticity of Vagal Motor Neurons in Response to Cardiac Ischemic Injury IScience. Mar, 2021 | Pubmed ID: 33665562 Similarities in Alcohol and Opioid Withdrawal Syndromes Suggest Common Negative Reinforcement Mechanisms Involving the Interoceptive Antireward Pathway Neuroscience and Biobehavioral Reviews. 06, 2021 | Pubmed ID: 33647322 Investigating the Effects of Brainstem Neuronal Adaptation on Cardiovascular Homeostasis Frontiers in Neuroscience. 2020 | Pubmed ID: 32508573 Diurnal Patterns of Gene Expression in the Dorsal Vagal Complex and the Central Nucleus of the Amygdala - Non-rhythm-generating Brain Regions Frontiers in Neuroscience. 2020 | Pubmed ID: 32477043 A Comprehensive Integrated Anatomical and Molecular Atlas of Rat Intrinsic Cardiac Nervous System IScience. Jun, 2020 | Pubmed ID: 32460006 Single-Cell Glia and Neuron Gene Expression in the Central Amygdala in Opioid Withdrawal Suggests Inflammation With Correlated Gut Dysbiosis Frontiers in Neuroscience. 2019 | Pubmed ID: 31333398 A Data-driven Modeling Approach to Identify Disease-specific Multi-organ Networks Driving Physiological Dysregulation PLoS Computational Biology. Jul, 2017 | Pubmed ID: 28732007 Single-Cell Transcriptional Analysis Reveals Novel Neuronal Phenotypes and Interaction Networks Involved in the Central Circadian Clock Frontiers in Neuroscience. 2016 | Pubmed ID: 27826225 Systemic Leukotriene B Receptor Antagonism Lowers Arterial Blood Pressure and Improves Autonomic Function in the Spontaneously Hypertensive Rat The Journal of Physiology. 10, 2016 | Pubmed ID: 27230966 The Role of the Gut-brain Axis in Alcohol Use Disorders Progress in Neuro-psychopharmacology & Biological Psychiatry. Feb, 2016 | Pubmed ID: 26188287 Intracellular Information Processing Through Encoding and Decoding of Dynamic Signaling Features PLoS Computational Biology. Oct, 2015 | Pubmed ID: 26491963 Computational Modeling of Cytokine Signaling in Microglia Molecular BioSystems. Dec, 2015 | Pubmed ID: 26440115 MicroRNA Network Changes in the Brain Stem Underlie the Development of Hypertension Physiological Genomics. Sep, 2015 | Pubmed ID: 26126791 Multiscale Model of Dynamic Neuromodulation Integrating Neuropeptide-induced Signaling Pathway Activity with Membrane Electrophysiology Biophysical Journal. Jan, 2015 | Pubmed ID: 25564868 Coordinated Dynamic Gene Expression Changes in the Central Nucleus of the Amygdala During Alcohol Withdrawal Alcoholism, Clinical and Experimental Research. Jan, 2013 | Pubmed ID: 22827539 Integrative Gene Regulatory Network Analysis Reveals Light-induced Regional Gene Expression Phase Shift Programs in the Mouse Suprachiasmatic Nucleus PloS One. 2012 | Pubmed ID: 22662235 Temporal Changes in Innate Immune Signals in a Rat Model of Alcohol Withdrawal in Emotional and Cardiorespiratory Homeostatic Nuclei Journal of Neuroinflammation. May, 2012 | Pubmed ID: 22626265 Rapid Temporal Changes in the Expression of a Set of Neuromodulatory Genes During Alcohol Withdrawal in the Dorsal Vagal Complex: Molecular Evidence of Homeostatic Disturbance Alcoholism, Clinical and Experimental Research. Oct, 2012 | Pubmed ID: 22486438 Adaptive Transcriptional Dynamics of A2 Neurons and Central Cardiovascular Control Pathways Experimental Physiology. Apr, 2012 | Pubmed ID: 22002872 Robust Dynamic Balance of AP-1 Transcription Factors in a Neuronal Gene Regulatory Network BMC Systems Biology. Dec, 2010 | Pubmed ID: 21167049 A Fast Carrier Chromatin Immunoprecipitation Method Applicable to Microdissected Tissue Samples Journal of Neuroscience Methods. Jul, 2008 | Pubmed ID: 18502516 Dynamic Transcriptomic Response to Acute Hypertension in the Nucleus Tractus Solitarius American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jul, 2008 | Pubmed ID: 18434436 From Promoter Analysis to Transcriptional Regulatory Network Prediction Using PAINT Methods in Molecular Biology (Clifton, N.J.). 2007 | Pubmed ID: 18314577 Quantifying Gene Network Connectivity in Silico: Scalability and Accuracy of a Modular Approach Systems Biology. Jul, 2006 | Pubmed ID: 16986625 Epidermal Growth Factor Receptor-induced Circadian-time-dependent Gene Regulation in Suprachiasmatic Nucleus Neuroreport. Sep, 2006 | Pubmed ID: 16932154 Systems Analysis of Circadian Time-dependent Neuronal Epidermal Growth Factor Receptor Signaling Genome Biology. 2006 | Pubmed ID: 16784547 A Universal Reference Sample Derived from Clone Vector for Improved Detection of Differential Gene Expression BMC Genomics. May, 2006 | Pubmed ID: 16677381 Chronic Alcohol Exposure Alters Transcription Broadly in a Key Integrative Brain Nucleus for Homeostasis: the Nucleus Tractus Solitarius Physiological Genomics. Dec, 2005 | Pubmed ID: 16189278 Importance of Input Perturbations and Stochastic Gene Expression in the Reverse Engineering of Genetic Regulatory Networks: Insights from an Identifiability Analysis of an in Silico Network Genome Research. Nov, 2003 | Pubmed ID: 14597654 PAINT: a Promoter Analysis and Interaction Network Generation Tool for Gene Regulatory Network Identification Omics : a Journal of Integrative Biology. 2003 | Pubmed ID: 14583114 Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods Sean J. O'Sullivan*1,2,3, Ankita Srivastava*1, Rajanikanth Vadigepalli1, James S. Schwaber1 1Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, 2Sidney Kimmel Medical College, Thomas Jefferson University, 3Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine JoVE 64014 Neuroscience
Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods Sean J. O'Sullivan*1,2,3, Ankita Srivastava*1, Rajanikanth Vadigepalli1, James S. Schwaber1 1Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, 2Sidney Kimmel Medical College, Thomas Jefferson University, 3Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine JoVE 64014 Neuroscience
