Julie R. McMullen

Discovery & Preclinical Dept

Baker Heart and Diabetes Institute

Julie R. McMullen

Professor Julie McMullen (PhD) heads the Cardiac Hypertrophy Laboratory at the Baker Heart and Diabetes Institute (VIC, AUSTRALIA) and is Head of the Discovery & Preclinical Domain at the Institute. Her research interests include physiological and pathological cardiac hypertrophy, heart failure, atrial fibrillation, gene therapy and cardiotoxicity. Prof McMullen is recognised internationally for research which defined the molecular distinction between physiological and pathological heart growth/cardiac hypertrophy in mouse models of health and disease. She discovered that a signalling pathway activated with exercise (PI3K pathway) was critical for physiological hypertrophy (e.g. athlete’s heart) but not pathological hypertrophy (e.g. setting of hypertension). She has published her research in leading journals including PNAS, Circulation, Circulation-Heart Failure, Nature Communications, Cell Reports, and Diabetes. She sits on the Editorial Board of Clinical Science and the American Journal of Physiology-Heart and Circulatory Physiology, and is a Fellow of the American Heart Association and International Society for Heart Research.

Publications

A Step-By-Step Method to Detect Neutralizing Antibodies Against AAV using a Colorimetric Cell-Based Assay

1Baker Heart and Diabetes Institute, 2Department of Physiology, Anatomy and Microbiology, La Trobe University, 3Florey Institute of Neuroscience and Mental Health, University of Melbourne, 4Department of Physiology, Centre for Muscle Research (CMR), The University of Melbourne, 5Department of Diabetes, Central Clinical School, Monash University, 6Baker Department of Cardiometabolic Health, The University of Melbourne, 7Department of Physiology and Department of Medicine Alfred Hospital, Monash University

JoVE 63419

 Biology