4.6
The nucleus, a prominent feature of eukaryotic cells, is a membrane-bound organelle that houses genetic information, the DNA, which is organized differentially depending on the lifecycle phase of the cell.
For instance, DNA protein complexes, known as chromatin, are suspended in nucleoplasm, a gel-like substance, and are particularly concentrated in a region called the nucleolus. When the cell's not dividing, chromatin fibers are loosely arranged and resemble tangled strings, allowing for easier access to the DNA during transcription. In contrast, when the cell's about to divide, chromatin fibers are compressed into chromosomes.
The nucleolus is also where the sub-units of ribosomes, structures necessary for translation, are made. Surrounding the nucleus is a double membrane nuclear envelope that contains protein lined pores to control the flow of ions, molecules, ribosomal parts and messenger RNA between the inner nucleoplasm and the cytoplasm.
While most cells in the body have one nucleus, some, like red blood cells, are anucleated. They lack a nucleus. Whereas others, such as skeletal muscle cells, are multinucleated with more than one nucleus due to structural and functional needs.
细胞核是一种有膜细胞器,在真核细胞中充当控制中心。它含有染色体DNA,后者控制基因表达,并精确地调控细胞内蛋白质的产生。相比之下,线粒体和叶绿体内的DNA仅执行这些细胞器特有的功能。
细胞核内DNA的排列
细胞核内的基因表达调控取决于许多因素,包括DNA结构。细胞核内的DNA缠绕在称为组蛋白的蛋白质…