31.19
输卵管是卵母细胞从卵巢到子宫的通道。每根输卵管长约 10 至 13 厘米,在解剖学上分为漏斗部、壶腹部、峡部和间质部分(或壁内部分)。漏斗部以其漏斗形状为特征,并具有延伸至腹腔的称为输卵管伞的延伸部分。这些伞在排卵期间起着关键作用,因为它们延伸到卵巢上以捕获释放的卵母细胞。
壶腹部占输卵管长度的一半…
子宫或输卵管是位于子宫两侧、长约10至13厘米的通道。
每根输卵管分为漏斗部、壶腹部和峡部。
漏斗部是一个漏斗状的开口,其表面装饰有指状突起,称为伞部,延伸至腹膜腔内。
接下来是壶腹部,这是最宽的部分,占输卵管长度的一半以上。
峡部是连接输卵管与子宫的最狭窄部分。
排卵前后,输卵管的伞部覆盖卵巢并扫过其表面。
在输卵管内,黏膜上皮的纤毛产生腹腔液中的液流,有助于卵母细胞的捕获。
上皮中的非纤毛分泌细胞和杆状细胞释放一种液体,以滋养卵母细胞。
黏膜周围的平滑肌层进行蠕动性收缩,通过推动卵子经过壶腹部,协助纤毛发挥作用。
通常,精子在壶腹部使卵母细胞受精,随后受精卵经峡部移行至子宫。
View the full transcript and gain access to JoVE Core videos
Q1: What are the three main sections of the uterine tube?
The uterine tube is divided into three main sections: the infundibulum, a funnel-shaped opening with finger-like fimbriae; the ampulla, the widest region comprising more than half the tube's length; and the isthmus, the narrowest section connecting to the uterus. Each section plays a distinct role in oocyte transport and fertilization.
Q2: How do fimbriae help capture the oocyte during ovulation?
During ovulation, the fimbriae extend over the ovaries and sweep their surface to capture the released oocyte. These finger-like projections cover the ovary and guide the oocyte into the infundibulum, initiating its journey through the uterine tube toward the uterus.
Q3: Why is the ampulla the most common site of fertilization?
The ampulla is the widest section of the uterine tube and provides an optimal environment for sperm and oocyte to meet. Typically, sperm fertilizes the oocyte in the ampulla before it travels through the isthmus to the uterus, making this region ideal for successful fertilization.
Q4: What role do cilia play in moving the oocyte through the uterine tube?
Ciliated epithelial cells in the uterine tube lining generate currents in the peritoneal fluid that transport the oocyte toward the uterus. These cilia work alongside peristaltic contractions of smooth muscle layers to move the oocyte through the ampulla and toward the isthmus.
Q5: What do secretory and peg cells contribute to oocyte transport?
Nonciliated secretory and peg cells in the uterine tube epithelium release a nourishing fluid that sustains the oocyte during its journey. This fluid provides essential nutrients to the oocyte as it travels from the ampulla through the isthmus to the uterus.
Q6: How do smooth muscle contractions assist oocyte movement?
Smooth muscle layers surrounding the mucosa contract peristaltically, complementing the work of cilia by propelling the oocyte through the uterine tube. These coordinated muscular contractions work with ciliary currents to ensure efficient transport of the oocyte toward the uterus for implantation.
Q7: What happens to the oocyte after fertilization in the ampulla?
After sperm fertilizes the oocyte in the ampulla, the resulting zygote travels through the isthmus, the narrowest part of the uterine tube, before reaching the uterus for implantation a few days later. This journey allows the embryo to develop while traveling to its implantation site.