Exocrine Glands

Exocrine glands are specialized structures that release substances through ducts onto an epithelial surface or into a body cavity, supporting functions such as digestion, protection, lubrication, and temperature regulation. Their secretory cells produce materials including enzymes, mucus, sweat, saliva, and sebum, which travel through ducts to reach specific destinations; secretion may occur through mechanisms that release products without destroying the cell, remove part of the cell, or rupture the entire cell. In biology, studying exocrine glands helps explain tissue organization, epithelial function, and organ physiology. Their activity is also relevant to disorders affecting digestion, skin, and glandular secretion.

Exocrine Glands - Related Videos

Education

JoVE Core - Anatomy and Physiology
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Exocrine Glands: Unicellular and Multicellular Glands

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2025

Exocrine glands are classified as unicellular and multicellular. The unicellular glands are scattered single cells, such as goblet cells, found in the mucous membranes of the small and large intestines. On the other hand, multicellular exocrine glands develop as secretory sheets, like the internal lining of the abdomen or chest. Such secretory sheets release their secretions directly into the lumen of these organs. In addition, some multicellular glands have deep-seated secretory units to...

Exocrine Glands: Methods of Secretion

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2023

Exocrine glands are those that release their secretions through ducts. Based on their mode of secretion, they can be classified into merocrine, apocrine, and holocrine. Merocrine Secretion Merocrine secretion is the most common type of exocrine secretion. The secretions are enclosed in vesicles and moved to the cell's apical surface, where the contents are released by exocytosis. For example, mucous, a watery secretion rich in the glycoprotein mucin, is a merocrine secretion. The eccrine glands...

Exocrine Glands: Types of Secretions

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2025

Exocrine glands produce and release a variety of glandular products. Exocrine glands can be classified into serous, mucous, or mixed types based on their secretory products. Serous glands produce watery secretions rich in digestive enzymes and proteins. The constituent cells of the serous gland have centrally located nuclei and eosinophilic secretory granules in the cytoplasm. The parotid gland is an example of a serous gland. It secretes saliva, which contains enzymes, such as lipases and...

Research

JoVE EoE - Large Animal Models

Superior Lacrimal Gland Removal: A Surgical Technique to Remove the Palpebral and Orbital Parts of Superior Lacrimal Gland from Rabbit Model

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2025

This video describes the surgical procedure to remove the two parts: palpebral and orbital of the superior lacrimal gland from a rabbit to create a dry eye disease model. This rabbit model is suitable for studies of ocular surface homeostasis, pathophysiology and ocular therapeutics.

Surgical Injury to the Mouse Pancreas through Ligation of the Pancreatic Duct as a Model for Endocrine and Exocrine Reprogramming and Proliferation

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Cited by 19 •

2015

This protocol describes an injury model involving the surgical ligation of the pancreatic duct in the adult mouse pancreas, resulting in severe injury that establishes an environment that allows beta cell neogenesis and proliferation. This model can be used as a tool to study mechanisms involved in beta cell formation.

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