Fats

Fats are energy-rich lipids composed primarily of glycerol joined to fatty acids, and they are essential for energy storage, insulation, and cellular function in biology. Their long hydrocarbon chains are largely nonpolar, making fats hydrophobic and poorly soluble in water; ester bonds link the fatty acids to glycerol in triglycerides, the main storage form. Organisms accumulate triglycerides in adipose tissue or other storage cells, where their oxidation releases energy during metabolism. Fatty acids also contribute to membrane lipids and serve as precursors for signaling molecules, linking fat metabolism to nutrition, physiology, development, and disease research.

Fats - Related Videos

Research

JoVE Journal - Medicine
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Transplantation Into the Mouse Ovarian Fat Pad

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Cited by 7 •

2016

We describe an ovarian fad pad transplantation assay suitable for studies of normal and transformed epithelia of the female reproductive tract. The mouse fat pad allows transplantation of large tissue fragments, is easily accessible for surgery and imaging, and provides the most favorable native environment for tissues of Müllerian origin.

Research

JoVE Journal - Developmental Biology

An Efficient Method to Obtain Dedifferentiated Fat Cells

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Cited by 4 •

2016

We have modified the conditions for DFAT cell generation and provide herein information regarding the use of an improved growth medium for the production of these cells.

Decellularizing Mammary Fat Pads: Deriving Extracellular Matrix Hydrogels from Mammary Fat Pads

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2023

This video describes a technique of deriving extracellular matrix hydrogels by decellularizing murine mammary fat pads following ex vivo irradiation for in vitro studies. This hydrogel helps to mimic the in vivo breast tissue environment post-radiation treatment to study tumor cell behavior.

Ovarian Fat Pad Transplantation Assay: An In Vivo Technique to Introduce Cells into Ovarian Fat Pad in Mouse Models

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2023

In this video, we demonstrate an assay for transplantation of experimental cells and tissue fragments into the mouse ovarian fat pad. This method can be used to monitor cell regeneration and tumor transformation via non-invasive techniques.

Fat Preference: A Novel Model of Eating Behavior in Rats

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Cited by 9 •

2014

Dietary fat content influences both energy intake and body fat composition in mammals. By examining rats’ preference for high fat food in a series of choice experiments, it is possible to test genetic differences and pharmacological interventions on their preference for high fat food.

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