Dialysis Cycle

A dialysis cycle is a repeated sequence in which blood or another fluid is processed to remove waste products and excess water when normal filtration is inadequate. In clinical hemodialysis, blood flows through a dialyzer containing a semipermeable membrane while dialysate moves in the opposite direction; diffusion transfers small solutes such as urea across the membrane, and pressure-driven ultrafiltration removes excess fluid. The cleansed blood then returns to the patient, and the cycle continues for a prescribed treatment period. Understanding each stage supports safe management of kidney failure, helps clinicians control electrolyte and fluid balance, and informs assessment of treatment adequacy.

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JoVE Science Education - Chemistry
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Dialysis: Diffusion Based Separation

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2023

Dialysis is a common technique used in biochemistry for separating molecules based on diffusion. In this procedure, a semipermeable membrane allows the movement of certain molecules based on size. This method can be applied to the removal of buffer, known as desalting, or exchanging buffer molecules or ions from a protein solution. This video covers the principles of dialysis along with a general procedure. Several applications of dialysis are reviewed, including the removal of gradient...

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JoVE Core - Analytical Chemistry

Dialysis

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2024

Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...

Dialysis

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2024

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF). Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

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2025

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...

Peritoneal Dialysis I: Introduction and Procedure

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2025

Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...

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