Transient Elastography

Transient elastography is a noninvasive technique that estimates tissue stiffness, most commonly in the liver, to support assessment of fibrosis and other structural changes in clinical practice. It delivers a brief mechanical vibration through the skin and uses ultrasound to track the resulting shear-wave propagation; faster wave movement indicates stiffer tissue, which is reported as a quantitative measurement. Clinicians use these measurements alongside clinical findings and laboratory data to help stage chronic liver disease, monitor changes over time, and reduce reliance on invasive biopsy, while recognizing that inflammation, congestion, and other conditions can influence results.

Transient Elastography - Related Videos

Research

JoVE Journal - Medicine

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

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2025

The goal of this protocol is to showcase the technique and use of point-of-care transient elastography for pediatric gastroenterologists monitoring hepatobiliary involvement and advanced cystic fibrosis liver disease in persons with cystic fibrosis.

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

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Cited by 16 •

2012

The procedure demonstrates the methodology of magnetic resonance elastography for monitoring the engineered outcome of adipose and osteogenic tissue engineered constructs through noninvasive local assessment of the mechanical properties using microscopic magnetic resonance elastography (μMRE).

Magnetic Resonance Elastography for Assessing Viscoelastic Properties

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2025

Source: Feng, Y., et al. Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography. J. Vis. Exp. (2022) This video demonstrates the method of magnetic resonance elastography (MRE) for assessing tissue viscoelastic properties by analyzing shear wave propagation through a gelatin phantom, mimicking brain tissue. The process involves generating and capturing shear waves with magnetic resonance imaging or MRI and analyzing wave...

Anisotropic Polyvinyl Alcohol Phantom Fabrication for Ultrasound Elastography: Procedure and Quality Controls

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2026

This protocol describes a robust, reproducible method for fabricating anisotropic polyvinyl alcohol (PVA) phantoms—essential tools for validating ultrasound elastography techniques targeting mechanically anisotropic soft tissues (e.g., skeletal muscle).

Education

JoVE Core - Electrical Engineering

Series R—L Circuit Transients

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2024

In a series resistor-inductor (R-L) circuit, closing the switch at the start of the time period simulates a three-phase short circuit, a fault condition where all three phases of an unloaded synchronous machine are short-circuited. When there is no fault impedance and no initial current, the initial voltage is determined by the phase angle of the source voltage. Using Kirchhoff's Voltage Law (KVL) to analyze this circuit helps determine the total asymmetrical fault current, which consists of...

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