Near Infrared Angiography
Near Infrared Angiography - Related Videos
01:17
Time-of-Flight Magnetic Resonance Angiography to Visualize Blood Vasculature
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2025
Position the patient's head inside the radiofrequency, or RF, coil of a magnetic resonance imaging, or MRI, machine.Initiate the time-of-flight magnetic resonance angiography or TOF MRA, a non-invasive technique for visualizing blood vessels.Select a tissue slice for imaging to visualize arteries and veins.Apply an RF pulse to excite the protons within the selected imaging slice. These protons release energy, which is detected as an MR signal.Repeated application of RF pulses saturates the MR...
01:22
Detection of Internal Carotid Artery Narrowing Using Digital Subtraction Angiography
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2025
Position a human patient with internal carotid stenosis, a condition characterized by narrowing of the internal carotid artery, on the imaging table for digital subtraction angiography (DSA). Insert an angiocatheter into the common carotid artery at the fourth cervical vertebra level. Capture a pre-contrast X-ray image to record background structures like bones and soft tissues using X-ray irradiation. Administer an iodine-based contrast medium into the carotid artery. The contrast medium...
10:24
Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography
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Cited by 13 •
2014
Indocyanine Green Angiography (or ICGA) performed by tail vein injection provides high quality ICGA time course images to characterize abnormalities in mouse choroid.
08:11
Infrared Spectroscopy
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2023
Source: Vy M. Dong and Zhiwei Chen, Department of Chemistry, University of California, Irvine, CA This experiment will demonstrate the use of infrared (IR) spectroscopy (also known as vibrational spectroscopy) to elucidate the identity of an unknown compound by identifying the functional group(s) present. IR spectra will be obtained on an IR spectrometer using the attenuated total reflection (ATR) sampling technique with a neat sample of the unknown.
09:43
In vivo Near Infrared Fluorescence (NIRF) Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis
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Cited by 32 •
2011
We detail a new near-infrared fluorescence (NIRF) catheter for 2-dimensional intravascular molecular imaging of plaque biology in vivo. The NIRF catheter can visualize key biological processes such as inflammation by reporting on the presence of plaque-avid activatable and targeted NIR fluorochromes. The catheter utilizes clinical engineering and power requirements and is targeted for application in human coronary arteries. The following research study describes a multimodal imaging strategy...
FAQs
After administration, near-infrared illumination excites the fluorescent tracer, and the camera records the emitted signal from circulating dye. This optical sequence converts tracer distribution into a dynamic view of vessels and regional perfusion rather than a purely static anatomical image. Because acquisition occurs in living tissue, clinicians can observe circulation during an active assessment or procedure.
Indocyanine green serves as the commonly used fluorescent tracer in this approach. Its administered signal provides the contrast needed for the imaging system to distinguish vascular structures and follow regional blood flow. That contrast is important because the resulting observations connect visible vessel anatomy with functional circulation, allowing assessment of whether tissue is receiving adequate perfusion rather than simply showing where vessels are located.
One important strength is the simultaneous view of structure and function. Vascular anatomy shows the location and arrangement of vessels, while fluorescence patterns indicate blood flow and regional perfusion. This distinction helps identify areas of inadequate circulation that may not be apparent from anatomy alone. It also makes the method useful for investigating microvascular function and tissue healing in living tissue.
Real-time viewing matters because perfusion can be assessed while treatment or surgery is underway, rather than only after the intervention. Clinicians can use the fluorescence signal to examine regional blood flow, locate poorly perfused areas, and make more informed decisions about tissue handling. This is especially relevant when viability depends on reliable circulation, as in grafts and flaps.
An assessment follows a simple sequence: administer the near-infrared fluorescent tracer, illuminate the tissue with near-infrared light, and capture the emitted fluorescence with a camera. The recorded signal displays vessels and regional blood flow in living tissue. During surgery, this workflow supplies immediate perfusion information that can be considered alongside the operative view when evaluating tissue circulation.
Clinicians can apply the method during reconstructive and vascular procedures to evaluate graft or flap viability. By showing whether relevant regions receive adequate blood flow, the imaging can reveal inadequate perfusion and support treatment decisions. Its value is therefore not limited to mapping vessels; it also helps assess whether transferred or repaired tissue has functional circulation during the clinical procedure.
In medical research, near infrared angiography provides a platform for studying microvascular function and tissue healing. Investigators can relate fluorescence-based observations of regional circulation to the condition of living tissue during an assessment. This subject-specific use extends the technique beyond surgical guidance, supporting investigation of how circulation contributes to tissue viability and recovery.