Pancreatic Head Tumors
Pancreatic Head Tumors - Related Videos
10:10
Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms
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2026
This protocol presents robotic duodenum-preserving total pancreatic head resection (R-DPPHRt) for intraductal papillary mucinous neoplasms (IPMNs). A video demonstrates the technique in a patient with main duct-IPMN, highlighting its feasibility as a minimally invasive, organ-preserving alternative to pancreaticoduodenectomy.
05:11
Treatment of Middle-segment Pancreatic Benign Tumor Using Laparoscopic Central Pancreatectomy with End-to-end Pancreatic Duct Reconstruction
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2026
This article presents laparoscopic central pancreatectomy with pancreatic duct end-to-end anastomosis as an important surgical approach for middle-segment pancreatic benign and low-grade malignant tumors.
03:59
Orthotopic Homograft Tumor Transplantation: A Technique to Generate Pancreatic Tumor Mouse Models
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2023
The video explains a stepwise surgical method for orthotopic implantation of a tumor fragment from a cancerous donor to the pancreas of a non-cancerous recipient mice for development of pancreatic cancer. Orthotopically implanted PDAC could recapture the tissue microenvironment of human pancreatic cancers than conventional subcutaneous (SC) models more accurately.
03:50
Irreversible Electroporation: A Technique for Ablating Pancreatic Tumor in Mouse
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2023
This video describes the procedure for performing irreversible electroporation (IRE) for non-thermal ablation of pancreatic tumors in mice. Both subcutaneous (SQ) and orthotopic tumors can be successfully treated with IRE in a highly controlled setting, facilitating various studies post-procedure.
09:18
Multianimal Magnetic Resonance Imaging for Tumor Measurements in Pancreatic Cancer Mouse Models
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2026
This protocol uses a multichamber bed for parallel magnetic resonance imaging (MRI) of up to four animals to detect pancreatic adenocarcinoma tumors in genetically engineered mouse models. This multianimal MRI protocol is fast and cost-effective for detecting and measuring tumors, facilitating animal selection for preclinical studies and longitudinal monitoring of tumor growth.
FAQs
A growing mass can compress or invade the common bile duct and pancreatic duct. This interference changes the normal movement of bile into the digestive tract and pancreatic secretions into the duodenum. The resulting obstruction helps explain why patients may develop jaundice, abdominal discomfort, or digestive problems, although the specific effects depend on which nearby structures are affected.
The pancreatic head lies near the common bile duct, pancreatic duct, blood vessels, and duodenum. Because of this close anatomical relationship, enlargement may affect several systems rather than producing only a localized symptom. Bile-flow disruption, altered pancreatic secretions, or involvement of adjacent structures can contribute to abdominal pain, digestive problems, jaundice, or weight loss.
Characterization identifies the nature and features of the lesion, while staging assesses how far the disease has extended. These assessments are clinically important because a mass may affect ducts, blood vessels, or the duodenum to different degrees. The combined findings help clinicians select an appropriate plan, including surgery, systemic therapy, radiation, or palliative care.
Evaluation typically combines imaging, laboratory testing, and tissue sampling when appropriate. Imaging helps characterize the lesion and assess its anatomical extent, while laboratory testing provides additional clinical information. Tissue sampling can contribute direct evidence about the lesion when it is considered appropriate. Using these approaches together supports diagnosis and helps determine the next clinical steps.
Clinicians first use available evaluation findings to characterize the lesion and determine its extent. The results are then considered together rather than relying on a single test. This diagnostic and staging process informs whether management should emphasize surgery, systemic therapy, radiation, or palliative care, linking the observed disease pattern with the most suitable treatment strategy.
Pancreatic head tumors are an important focus of clinical research because they can affect ducts, blood vessels, and the duodenum while producing varied clinical consequences. Research can examine how evaluation findings relate to disease extent and treatment selection. This context supports investigation of diagnostic approaches and management strategies involving surgery, systemic therapy, radiation, or palliative care.