Pass-through Window Protocol

The Pass-through Window Protocol is a controlled procedure for transferring medications, specimens, instruments, and other materials between adjacent clinical or laboratory areas while limiting contamination and preserving environmental separation. It relies on designated pass-through windows, surface disinfection, sealed or clean containers, and coordinated opening of the window so materials move through without directly connecting the two spaces. In medicine, this protocol supports infection prevention, sterile compounding, isolation practices, and efficient workflow in hospitals, pharmacies, and research facilities. Consistent implementation helps protect patients and staff, maintains cleanroom conditions, and reduces errors during the movement and handling of critical materials.

Pass-through Window Protocol - Related Videos

Education

JoVE Core - Pharmacology

First Pass Effect

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2023

Presystemic elimination, or the first-pass effect, is the metabolism of drugs that reduces their effective concentration at the site of action. Apart from the first-pass effect, the systemic bioavailability of the drug is also reduced by other factors, including incomplete absorption or chemical degradation of drugs. Depending on the route of administration, drugs can be metabolized in the liver, intestine, lungs, and vasculature. Orally administered drugs are first absorbed through the...

Single-pass Transmembrane Proteins

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2023

Integral membrane proteins are tightly associated with the cell membrane and play a crucial role in cell communication, signaling, adhesion, and transport of the molecules. Some integral membrane proteins are present only in the membrane monolayer. For example, the enzyme fatty acid amide hydrolase is present in the cytoplasmic side of the membrane monolayer. In contrast, another type of integral membrane protein, also known as a transmembrane protein, spans across the membrane. Transmembrane...

Research

JoVE Journal - Neuroscience

Surgical Protocol for a Large, Resealable Cranial Window Enabling Longitudinal, Multi-Modal Electrophysiology Recordings of Mouse Default Mode Network

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2026

This protocol describes a two-phase surgical method to create a large, resealable, dura-sparing cranial window in mice. This technique enables chronic, multi-modal electrophysiological recordings from distributed, deep-brain networks, such as the Default Mode Network, over several weeks.

Windowing Chicken Eggs for Developmental Studies

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Cited by 37 •

2007

The ease of accessibility of the embryo has allowed for experiments to map cell fates using several approaches, including chick quail chimeras and focal dye labeling. In this article we demonstrate one egg preparation method that has been optimized for long survival times.

Calvarial Window Generation in Mouse Model: A Surgical Procedure to Create Window in the Top Part of the Mouse Skull

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2023

In this video, we describe the surgical procedure to create a calvarial window for accessing the brain of a mouse model.

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