Prism Goggles

Prism goggles are optical devices that use wedge-shaped prisms to shift the apparent location of visual scenes, making them a controlled tool for studying how the brain links vision, movement, and spatial awareness. By refracting incoming light, the prisms create a predictable mismatch between where an object appears and where it is physically located; repeated pointing or reaching then drives visuomotor adaptation as the nervous system recalibrates motor commands and gradually reduces errors. In neuroscience, prism goggles help measure sensorimotor learning, investigate hemispheric and cerebellar contributions to spatial behavior, and evaluate prism adaptation approaches for conditions such as unilateral spatial neglect.

Prism Goggles - Related Videos

Research

JoVE Journal - Behavior
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Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy

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Cited by 26 •

2017

Here, we present a procedure for performing large-scale Ca2+ imaging with cellular-resolution across multiple cortical layers in freely moving mice. Hundreds of active cells can be observed simultaneously using a miniature, head-mounted microscope coupled with an implanted prism probe.

Research

JoVE Journal - Medicine

Virtual Prism Adaptation Therapy: Protocol for Validation in Healthy Adults

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Cited by 14 •

2020

This experimental protocol demonstrates the use of virtual prism adaptation therapy (VPAT) in healthy adults and the association between VPAT and functional near infrared spectroscopy to determine the effect of VPAT on cortical activation. Results suggest that VPAT may be feasible and could induce similar behavioral adaptation as conventional prism adaptation therapy.

Research

JoVE Journal - Neuroscience
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How to Create and Use Binocular Rivalry

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Cited by 72 •

2010

Binocular rivalry occurs when the eyes are presented with different images at the same location: one image dominates while the other is suppressed, and dominance alternates periodically. Rivalry is useful for investigating perceptual selection and visual awareness. Here we describe several easy methods for creating and using binocular rivalry stimuli.

Research

JoVE Journal - Engineering
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Evanescent Field Based Photoacoustics: Optical Property Evaluation at Surfaces

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Cited by 2 •

2016

Here we present a protocol to estimate material and surface optical properties using the photoacoustic effect combined with total internal reflection. This technique evanescent field-based photoacoustics can be used to create a photoacoustic metrology system to estimate materials' thicknesses, bulk and thin film refractive indices, and explore their optical properties.

Characterization of Immune Cell-derived Extracellular Vesicles and Studying Functional Impact on Cell Environment

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Cited by 2 •

2020

The present report highlights chronological requirements for extracellular vesicle (EV) isolation from microglia or blood macrophages. Microglia-derived EVs were evaluated as regulators of the neurite outgrowth while blood macrophage-derived EVs were studied in the control of C6 glioma cell invasion in in vitro assays. The goal is to better understand these EV functions as immune mediators in specific microenvironments.

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