Waiting
登录处理中...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Optisk styring og registrering af calciumsignal…
JoVE Journal
Medicine

这篇 内容 是免费权限的.

JoVE Journal Medicine
Optisk styring og registrering af calciumsignal med høj kapacitet i iPSC-afledte kardiomyocytter til toksicitetstest og fænotypisk lægemiddelscreening
Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Journal (Medicine)
Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Patient Derived Cell Culture and Isolation of CD133+ Putative Cancer Stem Cells from Melanoma
Journal (Medicine)
Patient Derived Cell Culture and Isolation of CD133+ Putative Cancer Stem Cells from Melanoma
 
Click here for the English version

Optisk styring og registrering af calciumsignal med høj kapacitet i iPSC-afledte kardiomyocytter til toksicitetstest og fænotypisk lægemiddelscreening

Article DOI: 10.3791/63175-v • 10:01 min • March 31st, 2022
March 31st, 2022 •
1, 1, 1, 1, 2, 3, 3, 3, 4,5,6
1LumiSTAR Biotechnology, Inc., 2NEXEL Co., Ltd., 3Institute of Pharmacology, College of Medicine, National Taiwan University, 4Manchester Heart Centre, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, 5Division of Cardiovascular Sciences, Manchester Academic Health Sciences Centre, University of Manchester, 6Division of Cell Matrix Biology and Regenerative Medicine, University of Manchester

章节

总结概括
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Den nuværende protokol beskriver optisk kontrol og observation af udløst cellulær aktivitet i iPSC-afledte kardiomyocytter (iPSC-CM'er) til screening af lægemidler med høj kapacitet og toksicitetstest. Multi-parametrisk kvantificering af fænotypiske mønstre i tid og rum vises. Langtidsvirkninger af lægemidler over timer eller sekventielle målinger over dage demonstreres.

Tags

Medicin udgave 181
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter