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JoVE Journal Cancer Research
Behoud van humane glioblastoom cellulaire diversiteit ex vivo met behulp van driedimensionale organoïde cultuur
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Behoud van humane glioblastoom cellulaire diversiteit ex vivo met behulp van driedimensionale organoïde cultuur

Article DOI: 10.3791/63745-v • 07:11 min • August 25th, 2022
August 25th, 2022 •
1, 2, 1, 2
1Department of Neurological Surgery, Cleveland Clinic, 2Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic

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Hier beschrijven we een methode om glioblastoom (GBM) organoïden te genereren uit primaire patiëntspecimens of van patiënten afgeleide celculturen en deze tot volwassenheid te houden. Deze GBM-organoïden bevatten fenotypisch diverse celpopulaties en recreëren tumormicro-omgevingen ex vivo.

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Kankeronderzoek Nummer 186
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