Transylvanian Institute of Neuroscience 1 article published in JoVE Neuroscience Behavioral And Physiological Analysis In A Zebrafish Model Of Epilepsy Hortense de Calbiac*1,2, Adriana Dabacan*3, Raul Muresan3, Edor Kabashi1,2, Sorana Ciura1,2 1University Paris Descartes Hospital Necker-Enfants Malades, Institut Imagine, 2Institut du Cerveau et de la Moelle épinière - ICM, Sorbonne Universités Paris, 3Transylvanian Institute of Neuroscience (TINS) Here, we present a protocol for the development and the characterization of a zebrafish model of epilepsy resulting from the transient inhibition of the DEPDC5 gene.