Hydrogel Gel Erosion
Hydrogel Gel Erosion - Related Videos
13:00
Modifying the Bank Erosion Hazard Index (BEHI) Protocol for Rapid Assessment of Streambank Erosion in Northeastern Ohio
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Cited by 5 •
2015
Streambank erosion potential can be evaluated and ranked using David Rosgen’s Bank Erosion Hazard Index (BEHI), however this protocol has significant limitations. Here we present protocol modifications to address time constraints, allow nonprofessionals to complete accurate assessments, and account for non-alluvial stream conditions in Northeast Ohio.
15:06
Synthesis of an Intein-mediated Artificial Protein Hydrogel
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Cited by 2 •
2014
We present the synthesis of a split-intein-mediated protein hydrogel. The building blocks of this hydrogel are two protein copolymers each containing a subunit of a trimeric protein that serves as a crosslinker and one half of a split intein. Mixing of the two protein copolymers triggers an intein trans-splicing reaction, yielding a polypeptide unit that self-assembles into a hydrogel. This hydrogel is highly pH- and temperature-stable, compatible with organic solvents, and easily incorporates...
07:25
Collagen Hydrogels
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2023
Collagen is another widely used biomaterial that has found popularity in commercial applications, such as photography. Collagen has more recently been used in tissue engineering applications, by creating hydrogels that provide structure to engineered tissue. This video introduces collagen as a biomaterial, demonstrates how it is harvested from porcine skin, and shows how the material is used to create a hydrogel for tissue engineering applications. Finally, several applications of the material...
08:33
Hydrogel Synthesis
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2023
Source: Amber N. Barron, Ashlea Patterson, and Taylor D. Sparks, Department of Materials Science and Engineering, The University of Utah, Salt Lake City, UT Hydrogels are a versatile class of cross-linked polymers produced through relatively simple procedures and with generally inexpensive materials. They can be formed from solution and involve a polymer backbone formed from monomer reagents, an initiator which makes the polymer reactive and a crosslinking species which binds the polymer chains...
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Generation and Recovery of β-cell Spheroids From Step-growth PEG-peptide Hydrogels
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Cited by 5 •
2012
The following protocol provides techniques for encapsulating pancreatic β-cells in step-growth PEG-peptide hydrogels formed by thiol-ene photo-click reactions. This material platform not only offers a cytocompatible microenvironment for cell encapsulation, but also permits user-controlled rapid recovery of cell structures formed within the hydrogels.
FAQs
The erosion pattern depends on how quickly material transport and loss occur relative to one another. If reaction or detachment is concentrated near the exposed boundary, the gel recedes from the surface inward. If the relevant processes occur throughout the swollen network, changes can be distributed through the gel, producing different structural and lifetime outcomes.
Hydrolysis, enzymatic degradation, and surface wear represent different routes to network loss. Hydrolysis or enzymes can cleave polymer chains, while wear can remove material directly. Each route changes polymer connectivity, so the gel may show different trajectories in mass, porosity, swelling, and mechanical properties. Identifying the route helps researchers interpret erosion measurements.
Transport and reaction rates determine whether material loss remains localized or progresses through the gel. Their balance affects how quickly the network loses material and how its swelling, porosity, strength, and usable lifetime evolve. In bioengineering design, considering these rates helps researchers relate an erosion profile to expected functional changes rather than treating mass loss as an isolated measurement.
Researchers can follow erosion by measuring mass over time and pairing that measurement with changes in swelling, porosity, and mechanical strength. Examining these properties together shows how material loss affects the network and its function. The combined profile is more informative for predicting gel lifetime than any single measurement alone.
To evaluate a hydrogel for controlled drug release, researchers need to connect erosion with changes in network structure and related properties. As mass is lost, swelling and porosity may change, altering the gel’s behavior over time. Erosion measurements therefore help determine whether a formulation can maintain the intended release period and structural performance.
In tissue engineering, wound care, and temporary scaffold design, erosion is a central lifetime consideration. A gel that changes too quickly may lose its intended structure or strength early, whereas slower change may extend its persistence. Tracking erosion alongside swelling, porosity, and mechanical properties helps researchers match material behavior with the time course required by the application.