Foramen Magnum
Foramen Magnum - Related Videos
09:32
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
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Cited by 5 •
2016
This protocol describes a procedure to track the evolution of mesial network measures in temporal lobe epilepsy (TLE) patients. It is based on the combination of intracranial recordings with a novel numerical technique for data analysis. Specifically, we present a protocol for network analyses of foramen ovale recordings.
10:52
Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
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Cited by 1 •
2022
The closure of a patent foramen ovale (PFO) is a catheter-based intervention to prevent PFO-associated stroke. The PFO-occlusion device is advanced through the femoral vein and deployed across the interatrial septum using transesophageal echocardiography (TEE) and fluoroscopic guidance. The following protocol provides a step-by-step guide for the PFO-closure intervention using a double-disc device.
05:02
Cerebellum Dissection and Slice Preparation: A Method to Generate Tissue Slices from Mouse Cerebellum
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2025
This video describes a method to generate tissue slices from the mouse cerebellum. The cerebellar slices can be used for organotypic culturing that provides insights into neurodevelopmental mechanisms, including myelination dynamics.
06:30
Protocol for Isolating the Mouse Circle of Willis
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Cited by 4 •
2016
We describe here a reproducible protocol for isolating the mouse circle of Willis.
03:42
Rapid Dissection and Dissociation of the Mouse Olfactory Epithelium for Single-Nucleus Suspensions
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Cited by 1 •
2025
This article provides a streamlined protocol for the dissection and dissociation of murine olfactory epithelium for the purpose of single-nucleus RNA sequencing.
FAQs
The opening provides the anatomical transition through which the medulla oblongata continues into the spinal cord. This arrangement maintains a continuous neural pathway from the cranial cavity into the vertebral canal, while the surrounding position helps align the brainstem with the vertebral column. Its significance is therefore both structural and functional.
Several systems share this passage: neural tissue, vertebral arteries, spinal roots of the accessory nerves, and protective meninges. Their coexistence shows that the foramen magnum is not simply a gap for the spinal cord. It coordinates transmission of nervous, vascular, and protective structures between the head and neck, making the craniovertebral junction anatomically integrated.
Position and shape influence how the skull connects with the vertebral column and how the brainstem aligns with it. For that reason, examining this opening helps relate cranial form to posture. In vertebrate biology, these relationships also provide a basis for considering how skull architecture and positional differences may reflect evolutionary patterns.
Begin by locating the opening in the occipital bone, then examine its position and shape at the cranial base. Next, trace its connections with the cranial cavity and vertebral canal, and identify the neural, vascular, nerve-root, and meningeal structures associated with its passage. This approach connects visible bone anatomy with transmitted structures and alignment.
Comparing its position and shape across vertebrate skulls can help organize observations about skull anatomy, posture, and evolution. The feature is especially informative when considered as part of the connection between the cranial cavity and vertebral column. Such analysis links a localized bony structure with broader patterns of vertebrate form.
The foramen magnum is relevant to clinical study because it lies at the craniovertebral junction, where the brainstem, vertebral column, vessels, nerve roots, and meninges are closely related. Reviewing these relationships helps frame the anatomy of conditions involving that junction. Its study therefore connects normal skull structure with clinical interpretation of this region.