Electron Pair Donation

Electron pair donation is the transfer of a pair of valence electrons from one species to another to form a chemical bond, a central principle in Lewis acid–base chemistry. Typically, a Lewis base uses a lone pair on a donor atom such as nitrogen, oxygen, sulfur, or a halide to bond with an electron-deficient Lewis acid, producing a coordinate covalent bond. This process forms coordination complexes, drives nucleophilic reactions, and influences molecular structure and reactivity. Understanding electron pair donation helps explain ligand binding to metal centers, acid–base reactions, catalysis, and key mechanisms in organic and inorganic chemistry.

Electron Pair Donation - Related Videos

Education

JoVE Core - Chemistry

VSEPR Theory and the Effect of Lone Pairs

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2020

Effect of Lone Pairs of Electrons on Molecule Geometry It is important to note that electron-pair geometry around a central atom is not the same thing as its molecular structure. Molecular structure describes the location of the atoms, not the electrons. The geometry that includes all electron pairs is the electron-pair geometry. The electron-pair geometries describe all regions where electrons are located, bonds as well as lone pairs. The structure that includes only the placement of the...

Electron Transport Chains

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2019

The final stage of cellular respiration is oxidative phosphorylation that consists of two steps: the electron transport chain and chemiosmosis. The electron transport chain is a set of proteins found in the inner mitochondrial membrane in eukaryotic cells. Its primary function is to establish a proton gradient that can be used during chemiosmosis to produce ATP and generate electron carriers, such as NAD+ and FAD, that are used in glycolysis and the citric acid cycle. The ETC is comprised of...

DNA Base Pairing

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2020

Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule, the amount of adenine (A) is equal to the amount of thymine (T); the amount of guanine (G) is equal to the amount of cytosine (C); and the sum of purines, A and G, is equal to the sum of pyrimidines, C and T (i.e., A+G = C+T). Later work by Watson and Crick revealed that in double-stranded DNA, A always forms two hydrogen bonds...

Research

JoVE Journal - Medicine
Free Sample

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

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Cited by 2 •

2025

The protocol here describes a high-fidelity porcine model of heart transplantation following donation after circulatory death utilizing ex vivo perfusion of the allograft.

Electron Carriers

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2019

Electron carriers can be thought of as electron shuttles. These compounds can easily accept electrons (i.e., be reduced) or lose them (i.e., be oxidized). They play an essential role in energy production because cellular respiration is contingent on the flow of electrons. Over the many stages of cellular respiration, glucose breaks down into carbon dioxide and water. Electron carriers pick up electrons lost by glucose in these reactions, temporarily storing and releasing them into the electron...

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