Atrophic Pharyngitis

Atrophic pharyngitis is a chronic disorder in which the lining of the pharynx becomes thin, dry, and less capable of producing protective secretions, often causing persistent throat discomfort. Reduced mucosal gland activity and progressive tissue atrophy can promote dryness, crust formation, irritation, foreign-body sensation, and difficulty swallowing, while chronic environmental or systemic factors may contribute. In clinical practice, recognizing this pattern helps distinguish atrophic pharyngitis from acute infection and other causes of sore throat. Evaluation guides management aimed at identifying underlying conditions, reducing irritation, restoring moisture, and monitoring persistent symptoms that may require further investigation.

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Education

JoVE Core - Medical-Surgical Nursing

Acute Pharyngitis

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2025

Introduction Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice. Classification Acute pharyngitis can be categorized based on its underlying cause: • Viral: Accounting for 40% to 60% of cases, viral infections are the most prevalent cause. Common cold viruses, influenza, adenovirus, and Epstein-Barr virus (mononucleosis) are among the most...

Chronic Pharyngitis

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2025

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa. Etiology It often arises from persistent viral or bacterial infections affecting sinuses and tonsils. Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

Streptococcal Pharyngitis

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2026

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...

Research

JoVE Journal - Developmental Biology

Ex Vivo Culture of Pharyngeal Arches to Study Heart and Muscle Progenitors and Their Niche

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Cited by 5 •

2015

Here, we present a protocol to culture pharyngeal arches to study the biology of heart and muscle progenitor cells and their microenvironment.

Visualization and Analysis of Pharyngeal Arch Arteries using Whole-mount Immunohistochemistry and 3D Reconstruction

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Cited by 15 •

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Here, we describe a protocol to visualize and analyze the pharyngeal arch arteries 3, 4, and 6 of mouse embryos using whole-mount immunofluorescence, tissue clearing, confocal microscopy, and 3D reconstruction.

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