Digital Signal Processing

Digital signal processing (DSP) is the use of computational methods to represent, analyze, modify, and generate signals such as audio, images, sensor measurements, and communications data. It works by sampling continuous signals, encoding measurements as numerical sequences, and applying algorithms such as filtering, Fourier analysis, convolution, and modulation to extract information or control signal behavior. In engineering, DSP supports noise reduction, speech and image enhancement, wireless communication, radar, biomedical instrumentation, and industrial monitoring. Because these operations can run on processors, microcontrollers, or programmable hardware, DSP enables precise, repeatable, and adaptable systems for real-time analysis and efficient data transmission.

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Research

JoVE Journal - Biology

Digital Microfluidics for Automated Proteomic Processing

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Cited by 30 •

2009

Digital Microfluidics is a technique characterized by the manipulation of discrete droplets (~nL - mL) on an array of electrodes by the application of electrical fields. It is well-suited for carrying out rapid, sequential, miniaturized automated biochemical assays. Here, we report a platform capable of automating several proteomic processing steps.

Calcified Artery Preparation and Processing with Preserved Morphology and RNA for Digital Spatial Profiling

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2026

This protocol includes a step-by-step workflow for calcified vascular specimens: tissue handling, decalcification, RNA validation, calcification level detection, and region-of-interest selection strategies on the Nanostring GeoMx Digital Spatial Profiler (DSP). The goal is to present a comprehensive method for preserving vascular tissue morphology and RNA for reliable spatial transcriptomic analysis.

Measurement of Neurophysiological Signals of Ignoring and Attending Processes in Attention Control

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Cited by 5 •

2015

Attention control comprises enhancement of target signals and attenuation of distractor signals. We describe an approach to measure separately but concurrently, the neurophysiology of attending and ignoring in sustained intermodal attention, utilizing a passive control condition during which neither process is continuously engaged.

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

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2025

This study employed voice signal analysis and machine learning methods, utilizing MATLAB to extract distinctive voice features for non-invasive early detection of asthma. The Support Vector Machine (SVM) and Random Forest (RF) algorithms demonstrated comparable performance in terms of overall classification accuracy, although SVM may achieve a better balance between sensitivity and specificity.

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

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Cited by 12 •

2012

The goal of our research is to correlate behavior to brain activity. Accurate behavioral measures and imaging techniques allow us to elucidate brain-behavior relationships.

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