Alternating Flow Speeds
Alternating Flow Speeds - Related Videos
07:28
Pitot-static Tube: A Device to Measure Air Flow Speed
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2023
Source: David Guo, College of Engineering, Technology, and Aeronautics (CETA), Southern New Hampshire University (SNHU), Manchester, New Hampshire A Pitot-static tube is widely used for measuring unknown speeds in air flow, for example, it is used to measure airplane airspeed. By Bernoulli's principle, airspeed is directly related to variations in pressure. Therefore, the Pitot-static tube senses the stagnation pressure and static pressure. It is connected to a manometer or pressure transducer...
09:35
Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis
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Cited by 3 •
2011
A reliable method to investigate outer hair cell (OHC) motile responses, including electromotility, slow motility and bending, is described. OHC motility is elicited by stimulation with an external alternating electrical field, and the method takes advantage of high-speed image recording, LED-based illumination, and last generation image analysis software.
07:20
A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation
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Cited by 11 •
2017
This study introduces a novel technique for the measurement and analysis of alternating speeds of blood microcirculation in a single experiment using a laser speckle contrast imager.
08:04
Controlling Flow Speeds of Microtubule-Based 3D Active Fluids Using Temperature
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Cited by 4 •
2019
The goal of this protocol is to use temperature to control the flow speeds of three-dimensional active fluids. The advantage of this method not only allows for regulating flow speeds in situ but also enables dynamic control, such as periodically tuning flow speeds up and down.
02:18
Alternative RNA Splicing
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2020
Alternative RNA splicing is the regulated splicing of exons and introns to produce different mature mRNAs from a single pre-mRNA. Unlike in constitutive splicing where a single gene produces a single type of mRNA, alternative splicing allows an organism to produce multiple proteins from a single gene and plays an important role in protein diversity. There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...
FAQs
Changing the speed changes how long fluid remains in a device and how rapidly dissolved substances or suspended particles are redistributed. Faster and slower phases therefore create different residence-time and mixing conditions within the same experiment. This can help investigators examine transport behavior under more than one flow state rather than relying on a single average condition.
The relevant biological effect depends partly on shear stress, the force generated as fluid moves along a surface. Alternating phases can expose cells, drugs, or samples to changing transport conditions, which may alter their contact with the device surface. This makes flow scheduling an important variable when designing biomedical tests involving surface interactions.
Compared with constant flow, alternating flow speeds can separate transport into deliberately defined phases. A constant rate provides one continuing condition, whereas repeated changes can vary residence time, shear, and mixing during the same run. The comparison is useful when a model must represent changing rather than steady fluid behavior.
An experiment begins by selecting the flow levels and the sequence in which they will alternate. Investigators then create those phases by adjusting pumping conditions or the pressure gradient driving the fluid. The resulting design should relate each phase to the transport behavior or biological interaction being examined, so changes in outcome can be interpreted against the programmed flow pattern.
In microfluidic medicine, the strategy can be applied to devices that transport fluids, cells, drugs, or biological samples. Alternating conditions may support controlled mixing and allow testing of how transported materials interact with device surfaces. These capabilities are relevant to laboratory models and biomedical testing systems where transport conditions influence the experiment.
For diagnostic assays, changing the flow pattern can improve control of mixing between dissolved components or suspended particles. That control may help investigators study assay behavior under defined transport conditions, although the useful pattern depends on the device and the substances being moved. The broader goal is more precise biomedical measurement and testing.
In controlled therapeutic-delivery research, alternating speeds provide a way to investigate how flow conditions affect the movement of drugs through a device. By changing residence time, mixing, and surface contact, researchers can evaluate transport behavior before considering future delivery approaches. The concept represents a research direction rather than an established clinical treatment.