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Generering av Subkutan og Intrahepatisk menneskeleverkreft xenografts i immunodeficient Mus

Article DOI: 10.3791/50544-v • 10:35 min • September 25th, 2013
September 25th, 2013 •
1, 1, 1, 1, 1, 2, 3, 1,3
1Toronto General Research Institute, University Health Network, 2Department of Pathology, University Health Network, 3Division of General Surgery, University Health Network

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Menneskelige tumorxenotransplantater i immunodeficient mus er verdifulle verktøy for å studere kreft biologi. Spesifikke protokoller for å generere subkutane og intrahepatiske xenografts fra humane leverkreft celler eller tumor fragmenter er beskrevet. Leveren regenerering indusert ved delvis hepatectomy i mottaker mus er presentert som en strategi for å lette intrahepatisk engraftment.

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Medisin lever svulster hepatectomy dyremodeller leverkreft xenograft kreft leverskader subkutan intrahepatisk orthotopic mus menneske immunodeficient
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