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Journal / Biochemistry / Crystallization of ABC Transporter Membrane… / A Bicelle Crystallization Setup for ABC…
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Biochemistry

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JoVE Journal Biochemistry
A Bicelle Crystallization Setup for ABC Transporter Membrane Proteins to Advance Drug Development (Video) | JoVE
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A Bicelle Crystallization Setup for ABC Transporter Membrane Proteins to Advance Drug Development (Video) | JoVE

Crystallization of ABC Transporter Membrane Proteins in Lipidic Bicelles

Article DOI: 10.3791/65828-v • 01:55 min • August 25th, 2023
August 25th, 2023 •
1, 1, 1,2, 1
1Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 2Department of Biochemistry, Faculty of Medicine and Dentistry, University of Alberta

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ABCG5/G8 Bice lipidique Cristallographie aux rayons X Protéines membranaires Bicouche lipidique Détergents Stabilité Uniformité Caractérisation structurale Bicelles Phospholipides Cristaux de diffraction de haute qualité Structure haute résolution Conformation native Fonctionnalité Cristaux tridimensionnels ABCG5/G8 hétérodimérique solubilisé par détergent Bicelles DMPC/CHAPSO Cholestérol Diffusion de vapeur Cristallisation des protéines
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