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JoVE Core

Cell Biology

Video textbook for undergraduate courses: Visualized concepts and experiments

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43 Chapters

550+ Videos

4,050+ Multiple Choice Questions

Table of Contents

Chapter 1

Cells, Genomes, and Evolution

15 Videos

26 Minutes

What are Cells?

What are Cells?

43.8K views

The Tree of Life – Bacteria, Archaea, and Eukaryotes

The Tree of Life – Bacteria, Archaea, and Eukaryotes

20.4K views

Prokaryotic Cells

Prokaryotic Cells

44.9K views

Eukaryotic Compartmentalization

Eukaryotic Compartmentalization

16.6K views

Eukaryotic Evolution

Eukaryotic Evolution

39.1K views

Animal and Plant Cell Structure

Animal and Plant Cell Structure

42.5K views

Cytoplasm

Cytoplasm

7.2K views

The Nucleus

The Nucleus

6.6K views

The DNA Helix

The DNA Helix

27.6K views

The Central Dogma

The Central Dogma

30.5K views

Mutations

Mutations

41.7K views

Genome Size and the Evolution of New Genes

Genome Size and the Evolution of New Genes

2.9K views

Gene Families

Gene Families

3.1K views

Gene Evolution – Fast or Slow?

Gene Evolution – Fast or Slow?

3.2K views

Types of Genetic Transfer Between Organisms

Types of Genetic Transfer Between Organisms

5.9K views

Chapter 2

Biochemistry of the Cell

12 Videos

29 Minutes

The Periodic Table and Organismal Elements

The Periodic Table and Organismal Elements

21.3K views

Functional Groups

Functional Groups

23.4K views

Types of Chemical Bonds

Types of Chemical Bonds

22.6K views

Noncovalent Attractions in Biomolecules

Noncovalent Attractions in Biomolecules

18.8K views

Polymers

Polymers

22.8K views

What are Lipids?

What are Lipids?

9.8K views

Structure of Lipids

Structure of Lipids

13K views

Chemistry of Carbohydrates

Chemistry of Carbohydrates

9.8K views

Nucleic Acids

Nucleic Acids

8.4K views

Protein and Protein Structures

Protein and Protein Structures

15.3K views

pH Regulation in Cells

pH Regulation in Cells

7K views

Chemistry of the Cell

Chemistry of the Cell

8.9K views

Chapter 3

Energy and Catalysis

22 Videos

30 Minutes

The First Law of Thermodynamics

The First Law of Thermodynamics

7K views

The Second Law of Thermodynamics

The Second Law of Thermodynamics

6.2K views

Enthalpy within the Cell

Enthalpy within the Cell

7.1K views

Entropy within the Cell

Entropy within the Cell

12.2K views

An Introduction to Free Energy

An Introduction to Free Energy

9.7K views

Endergonic and Exergonic Reactions in the Cell

Endergonic and Exergonic Reactions in the Cell

16.9K views

The Equilibrium Binding Constant and Binding Strength

The Equilibrium Binding Constant and Binding Strength

9.5K views

Free Energy and Equilibrium

Free Energy and Equilibrium

7.4K views

Non-equilibrium in the Cell

Non-equilibrium in the Cell

5K views

Oxidation and Reduction of Organic Molecules

Oxidation and Reduction of Organic Molecules

8.6K views

Introduction to Enzymes

Introduction to Enzymes

28.5K views

Enzymes and Activation Energy

Enzymes and Activation Energy

19.4K views

Introduction to Enzyme Kinetics

Introduction to Enzyme Kinetics

28K views

Turnover Number and Catalytic Efficiency

Turnover Number and Catalytic Efficiency

17.2K views

Catalytically Perfect Enzymes

Catalytically Perfect Enzymes

4.5K views

Introduction to Mechanisms of Enzyme Catalysis

Introduction to Mechanisms of Enzyme Catalysis

9.4K views

Ligand Binding and Linkage

Ligand Binding and Linkage

3.7K views

Cooperative Allosteric Transitions

Cooperative Allosteric Transitions

2.8K views

Ribozymes

Ribozymes

3K views

ATP Energy Storage and Release

ATP Energy Storage and Release

12.6K views

ATP and Macromolecule Synthesis

ATP and Macromolecule Synthesis

6.4K views

Coupled Reactions

Coupled Reactions

9.5K views

Chapter 4

Introduction to Metabolism

12 Videos

16 Minutes

Overview of Metabolism

Overview of Metabolism

35.8K views

Carbohydrate Metabolism

Carbohydrate Metabolism

12.9K views

Glycolysis: Preparatory Phase

Glycolysis: Preparatory Phase

15.3K views

Glycolysis: Pay-off Phase

Glycolysis: Pay-off Phase

11.1K views

Fates of Pyruvate

Fates of Pyruvate

9.6K views

Role of Reduced Coenzymes NADH and FADH₂

Role of Reduced Coenzymes NADH and FADH₂

15K views

Overview of Nitrogen Metabolism

Overview of Nitrogen Metabolism

10.3K views

Overview of Fatty Acid Metabolism

Overview of Fatty Acid Metabolism

32.9K views

Sugars as Energy Storage Molecules

Sugars as Energy Storage Molecules

9.2K views

Fats as Energy Storage Molecules

Fats as Energy Storage Molecules

26.1K views

Regulation of Metabolism

Regulation of Metabolism

10.6K views

Positive and Negative Feedback Loops

Positive and Negative Feedback Loops

21.9K views

Chapter 5

Protein Structure

10 Videos

22 Minutes

What are Proteins?

What are Proteins?

18.3K views

Protein Organization

Protein Organization

8.2K views

Protein Folding

Protein Folding

9.9K views

Protein Families

Protein Families

3.7K views

Conservation of Protein Domains

Conservation of Protein Domains

3.5K views

Globular and Fibrous Proteins

Globular and Fibrous Proteins

4.9K views

Intrinsically Disordered Proteins

Intrinsically Disordered Proteins

2.5K views

Protein Complex Assembly

Protein Complex Assembly

2.3K views

Conjugated Proteins

Conjugated Proteins

2.9K views

Amyloid Fibrils

Amyloid Fibrils

6K views

Chapter 6

Protein Function

12 Videos

25 Minutes

Ligand Binding Sites

Ligand Binding Sites

8.3K views

Protein-Protein Interfaces

Protein-Protein Interfaces

4.1K views

Conserved Binding Sites

Conserved Binding Sites

1.8K views

Cofactors and Coenzymes

Cofactors and Coenzymes

12.2K views

Cooperative Allosteric Transitions

Cooperative Allosteric Transitions

2.5K views

Protein Kinases and Phosphatases

Protein Kinases and Phosphatases

4K views

GTPases and their Regulation

GTPases and their Regulation

2.5K views

Covalently Linked Protein Regulators

Covalently Linked Protein Regulators

1.8K views

Protein Complexes with Interchangeable Parts

Protein Complexes with Interchangeable Parts

2K views

Mechanical Protein Function

Mechanical Protein Function

2.2K views

Structural Protein Function

Structural Protein Function

2.9K views

Protein Networks

Protein Networks

2.5K views

Chapter 7

Structure and Organization of DNA

10 Videos

21 Minutes

DNA as a Genetic Template

DNA as a Genetic Template

8.3K views

Structure of a Gene

Structure of a Gene

14.5K views

Chromosome Structure

Chromosome Structure

5.7K views

The Nucleosome

The Nucleosome

4.1K views

Chromatin Packaging

Chromatin Packaging

9K views

Euchromatin

Euchromatin

3.3K views

Heterochromatin

Heterochromatin

4K views

Histone Modification

Histone Modification

3.9K views

Lampbrush Chromosomes

Lampbrush Chromosomes

2.6K views

Polytene Chromosomes

Polytene Chromosomes

3.2K views

Chapter 8

DNA Replication and Repair

17 Videos

34 Minutes

Base-pairing and DNA Repair

Base-pairing and DNA Repair

74.4K views

The DNA Replication Fork

The DNA Replication Fork

16.9K views

Lagging Strand Synthesis

Lagging Strand Synthesis

15K views

The Replisome

The Replisome

8.3K views

Proofreading

Proofreading

7.4K views

Replication in Prokaryotes

Replication in Prokaryotes

26.1K views

Replication in Eukaryotes

Replication in Eukaryotes

15.7K views

Telomeres and Telomerase

Telomeres and Telomerase

6.3K views

Overview of DNA Repair

Overview of DNA Repair

8.6K views

Base Excision Repair

Base Excision Repair

4.4K views

Nucleotide Excision Repair

Nucleotide Excision Repair

4.3K views

Mismatch Repair

Mismatch Repair

5.6K views

Fixing Double-strand Breaks

Fixing Double-strand Breaks

3.7K views

Homologous Recombination

Homologous Recombination

5.3K views

Gene Conversion

Gene Conversion

2.6K views

DNA Damage Can Stall the Cell Cycle

DNA Damage Can Stall the Cell Cycle

2.8K views

Restarting Stalled Replication Forks

Restarting Stalled Replication Forks

2.1K views

Chapter 9

Transcription: DNA to RNA

18 Videos

35 Minutes

What is Gene Expression?

What is Gene Expression?

10K views

RNA Structure

RNA Structure

5.8K views

Types of RNA

Types of RNA

7.9K views

Transcription

Transcription

28.7K views

Bacterial RNA Polymerase

Bacterial RNA Polymerase

11K views

Eukaryotic RNA Polymerases

Eukaryotic RNA Polymerases

8.4K views

General Transcription Factors

General Transcription Factors

6.1K views

RNA Polymerase II Accessory Proteins

RNA Polymerase II Accessory Proteins

3.5K views

Transcription Elongation Factors

Transcription Elongation Factors

4.1K views

Pre-mRNA Processing: Modification of pre-mRNA Ends

Pre-mRNA Processing: Modification of pre-mRNA Ends

12.8K views

Pre-mRNA Processing: RNA Splicing

Pre-mRNA Processing: RNA Splicing

6K views

Chromatin Structure and RNA Splicing

Chromatin Structure and RNA Splicing

3K views

Alternative RNA Splicing

Alternative RNA Splicing

4.3K views

Nuclear Export of mRNA

Nuclear Export of mRNA

4.8K views

Transfer RNA Synthesis

Transfer RNA Synthesis

3.2K views

Ribosomal RNA Synthesis

Ribosomal RNA Synthesis

3.8K views

The Nucleolus

The Nucleolus

5K views

Additional Subnuclear Structures

Additional Subnuclear Structures

2.3K views

Chapter 10

Translation: RNA to Protein

11 Videos

24 Minutes

Translation

Translation

16.6K views

Ribosomes

Ribosomes

9.2K views

tRNA Activation

tRNA Activation

7.6K views

Initiation of Translation

Initiation of Translation

7.2K views

Termination of Translation

Termination of Translation

6.1K views

Improving Translational Accuracy

Improving Translational Accuracy

3.2K views

Nonsense-mediated mRNA Decay

Nonsense-mediated mRNA Decay

3K views

Molecular Chaperones and Protein Folding

Molecular Chaperones and Protein Folding

14K views

The Proteasome

The Proteasome

3.9K views

Regulated Protein Degradation

Regulated Protein Degradation

2.8K views

Proteins: From Genes to Degradation

Proteins: From Genes to Degradation

4K views

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