Ventriculomegaly

Ventriculomegaly is an enlargement of the brain’s fluid-filled ventricles, a finding that can indicate altered cerebrospinal fluid dynamics or underlying neurological disease. It develops when cerebrospinal fluid production, circulation, or absorption becomes disrupted, often because an obstruction increases pressure and expands the ventricular spaces; however, enlargement does not always mean hydrocephalus. In neuroscience, clinicians and researchers assess ventriculomegaly with prenatal or postnatal neuroimaging, including ultrasound, magnetic resonance imaging, and computed tomography, to evaluate its severity, cause, and progression. These assessments support diagnosis, monitoring, counseling, and treatment planning for conditions affecting brain development or intracranial pressure.

Ventriculomegaly - Related Videos

Research

JoVE Journal - Neuroscience

Modeling Posthemorrhagic Hydrocephalus of Prematurity in Rats

0 Views •

Cited by 3 •

2025

Posthemorrhagic hydrocephalus of prematurity (PHHP) can be modeled in neonatal rats by combining chorioamnionitis and intraventricular hemorrhage. The combination of these prenatal and postnatal events accurately recapitulates the clinical hallmarks of PHHP, including macrocephaly, ventriculomegaly, and elevated intracranial pressure, through the lifespan.

View All Results

FAQs

Related Topics