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Journal / Biochemistry / Förbättra inympningen av humana inducerade…
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Biochemistry

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JoVE Journal Biochemistry
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Förbättra inympningen av humana inducerade pluripotenta stamcells-härledda Kardiomyocyter via en övergående hämning av Rho-Kinas aktivitet

Article DOI: 10.3791/59452-v • 08:00 min • July 10th, 2019
July 10th, 2019 •
1, 1, 1,2, 1, 1,3, 1, 1, 1, 2, 1, 1
1Department of Biomedical Engineering, School of Medicine, School of Engineering, University of Alabama at Birmingham, 2Division of Cardiovascular Diseases, School of Medicine, School of Engineering, University of Alabama at Birmingham, 3Department of Cardiac Surgery, The Second Xiangya Hospital of Central South University

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I detta protokoll visar och utvecklar vi hur man använder humana inducerade pluripotenta stamceller för kardiomyocyte differentiering och rening, och vidare, om hur man kan förbättra sin transplantation effektivitet med Rho-associerad proteinkinashämmare förbehandling i en mus hjärtinfarkt modell.

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Biokemi pluripotenta stamceller kardiomyocyter cellterapi hjärtinfarkt Rho Kinas ROCK inhibitor
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