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JoVE Journal Neuroscience
Caenorhabditis elegans como um sistema modelo para descobrir compostos bioativos contra neurotoxicidade mediada por poliglutamina
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Caenorhabditis elegans como um sistema modelo para descobrir compostos bioativos contra neurotoxicidade mediada por poliglutamina

Article DOI: 10.3791/63081-v • 08:16 min • September 21st, 2021
September 21st, 2021 •
*1, *2, 1,3, 1, 3, 3, 1
1Institute for Food Nutrition and Human Health, School of Food Science and Engineering, South China University of Technology, 2School of Bioscience and Bioengineering, Hebei University of Economics and Business, 3Perfect Life & Health Institute
* These authors contributed equally

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Aqui, apresentamos um protocolo para avaliar as atividades neuroprotetoras de compostos de teste em Caenorhabditis elegans, incluindo agregação de poliglutamina, morte neuronal e comportamento de quimioavoidance, bem como uma integração exemplar de fenômenos múltiplos.

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Neurociência Edição 175
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